A5085147723- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Bariatric Surgery and Outcomes
- Birth, Development, and Health
- Thyroid Disorders and Treatments
- Airway Management and Intubation Techniques
- Thyroid Cancer Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Tracheal and airway disorders
- Neuroblastoma Research and Treatments
- Neuroendocrine Tumor Research Advances
- Pancreatic and Hepatic Oncology Research
- Neonatal Health and Biochemistry
- Diet and metabolism studies
- Electrolyte and hormonal disorders
- Pituitary Gland Disorders and Treatments
- Pancreatic function and diabetes
- Maternal and Neonatal Healthcare
- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Parathyroid Disorders and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Skin Diseases and Diabetes
- Anorectal Disease Treatments and Outcomes
- Global Healthcare and Medical Tourism
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2018-2024
Hospital Clínico San Carlos
2001-2024
Hospital Universitario de Móstoles
2008-2011
Objectives To assess whether Mediterranean Diet (MedDiet)-based medical nutrition therapy facilitates near-normoglycemia in women with gestational diabetes mellitus (GDMw) and observe the effects on adverse pregnancy outcomes. Research design methods This is a secondary analysis of St Carlos GDM Prevention Study, conducted between January December 2015 Hospital Clínico San (Madrid, Spain). One thousand consecutive normoglycemia were included before 12 weeks (GWs), 874 final analysis. Of...
<b><i>Aims:</i></b> The aim of the study was to evaluate effect a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on composite adverse maternofoetal outcomes women normoglycemia during pregnancy. <b><i>Methods:</i></b> This sub-analysis St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic were analysed (697). They randomized (at 8–12th weeks) to: standard-care control group (337),...
A Mediterranean diet (MedDiet)-based intervention reduces the rate of immediate postpartum maternal metabolic disorders. Whether these effects persist long-term remains to be determined. total 2526 normoglycemic women were randomized before 12th gestational week (GW). IG followed a MedDiet with extra virgin olive oil (EVOO) (>40 mL/day) and handful nuts daily, whereas CG had restrict all kinds dietary fat. At 3 months postpartum, motivational lifestyle interview was held. The endpoint...
The pathophysiology of gestational diabetes mellitus (GDM) comprises clinical and genetic factors. In fact, GDM is associated with several single nucleotide polymorphisms (SNPs). This study aimed to build a prediction model combining risk A total 1588 pregnant women from the San Carlos Cohort participated in present study, including 1069 (67.3%) Caucasian (CAU) 519 (32.7%) Latin American (LAT) individuals, 255 (16.1%) had GDM. incidence was similar both groups (16.1% CAU 16.0% LAT)....
Abstract Aims To assess whether patients with Type 2 diabetes mellitus and unrecognized peripheral arterial disease (PAD), detected by the ankle–brachial index (ABI), have poorer cardiovascular risk factor management (CVRFs) receive fewer medications than previously diagnosed coronary heart (CHD) or cerebrovascular (CVD). Methods In 31 centres throughout Spain, 1303 were screened for PAD using ABI. Patient history of CHD CVD treatment control CVRFs recorded. Results Forty‐one had an ABI >...
Gestational diabetes mellitus (GDM) entails a complex underlying pathogenesis, with specific genetic background and the effect of environmental factors. This study examines link between set single nucleotide polymorphisms (SNPs) associated development GDM in pregnant women different ethnicities, evaluates its potential modulation clinical intervention based on Mediterranean diet. 2418 from our hospital-based cohort screened for January 2015 to November 2017 (the San Carlos Cohort, randomized...
The optimal maternal levels of thyroid hormones (TH) during the first trimester gestation have not been established, nor has ideal moment to initiate levothyroxine treatment (LT) improve evolution and fetal development. Cut-off points for Thyroid-stimulating hormone (TSH) &lt;2.5 µIU/mL free thyroxine (FT4)&gt;7.5 pg/mL recommended. There are no data on whether initiation LT &lt;9th Gestational Week (GW) can a favourable impact. Objective To define TSH/FT4 percentiles...
Obesity is a risk factor for the development of gestational diabetes mellitus (GDM). However, most optimal type nutritional intervention to prevent GDM in high-risk women not clearly defined. This study investigates if treatment based on Mediterranean diet (MedDiet) before 12th week (GW) at high due body mass index (BMI) ≥ 25 kg/m2 reduces rate and metabolic syndrome (MetS) 3 years postpartum. We performed post-hoc analysis San Carlos Gestational Prevention Study. A total 735 with BMI were...
The San Carlos Gestational Diabetes Mellitus (GDM) prevention study, a nutritional intervention RCT based on Mediterranean Diet (MedDiet), has been shown to reduce the incidence of GDM. objective this study is investigate relationship leptin, adiponectin, interleukin-6 (IL-6), tumour necrosis factor-alpha (TNF-α), insulin and HOMA-IRand circulating miRNAs (miR-29a-3p, miR-103a-3p, miR-132-3p, miR-222-3p) with appearance GDM MedDiet-based intervention, at 24−28 gestational weeks (GW), in...
A pre-gestational thyroid reserve of iodine is crucial to guarantee the increased demand for hormone production early pregnancy. An intake ≥150 µg/day currently recommended. The objective this study was assess average food-based consumption in pregnant women at their first prenatal visit (<12 gestational weeks), and its association with adverse materno-fetal events (history miscarriages, fetal losses, Gestational Diabetes, prematurity, caesarean sections, new-borns large/small age). Between...
Gestational diabetes mellitus (GDM) pathophysiology comprises clinical and genetic factors. In fact, GDM has been associated with several single nucleotide polymorphisms (SNPs). This study aimed to build a prediction model of combining risk A total 1588 pregnant women from the San Carlos Cohort participated in present study, 1069 (67.3%) Caucasian (CAU) 519 (32.7%) Latin American (LAT), 255 (16.1%) GDM. The incidence was similar both groups (16.1% CAU 16.0% LAT). Genotyping performed by...
Obesity is a risk factor for the development of gestational diabetes mellitus (GDM). However, most optimal type nutritional intervention to prevent GDM in high-risk women not clearly defined. This study investigates if treatment based on Mediterranean diet (MedDiet) before 12th week (GW) at high due body mass index (BMI)≥25kg/m2, reduces rate and metabolic syndrome (MetS) 3 years postpartum. We performed post-hoc analysis San Carlos Gestational Prevention Study. A total 735 with BMI≥25kg/m2...
Low birth weight (LBW) is associated to poor health outcomes. Its causes include maternal lifestyle, obstetric factors, and fetal (epi)genetic abnormalities. This study aims increase the knowledge regarding genetic background of LBW by analyzing its association with a set 110 variants related gestational diabetes mellitus, in setting nutritional intervention Mediterranean diet. The analysis follows multifactorial approach, including information 1,642 pregnant women, along their...
Objective: To identify risk factors(RF) related to abnormal glucose regulation(AGR) 3 years postpartum according 3-month-postpartum status.
 Research design: Normoglycemic pregnant women of the St. Carlos Gestational Study included before gestational week 12, during 2015-2017. Of 3,036 eligible women, 2529 were followed-up until delivery: 1400 participated in follow-up. AGR defined as fasting serum (FSG)&gt;5.6 mmol/L and/or HbA1c &gt;5.7% (39 mmol/mol) 2h-SG ≥140/mg/dL after...
Evaluation of the influence potential risk factors (RFs) on glycemic changes at 3 years postpartum. The status 1400 women, in absence a new pregnancy, was evaluated months (3 m) and y) postpartum, after participation St. Carlos Gestational Study (2228 normoglycemic pregnant women followed from before gestational week 12 to delivery, 2015-2017). Abnormal glucose regulation (AGR) defined as fasting serum ≥ 100 mg/dL and/or HbA1c 5.7% 2 h 75 g OGTT 140 mg/dL. In total, modifiable unmodifiable...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
El quiste paratiroideo es una enfermedad muy rara que puede llevar a un diagnóstico y tratamiento inadecuado. Se presenta caso clínico junto revisión de la literatura disponible sobre patogénesis proceso terapéutico esta entidad. Nuestro paciente fue remitido por hipercalcemia siendo diagnosticado hiperparatiroidismo primario. Las pruebas localización mostraron lesión quística con niveles elevados PTHi (Paratohormona intacta) en citología, lo permitió el correcto paratiroidectomía inferior...