A5006164167- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Neuroendocrine Tumor Research Advances
- Adrenal Hormones and Disorders
- Thyroid Disorders and Treatments
- LGBTQ Health, Identity, and Policy
- Thyroid and Parathyroid Surgery
- Hormonal Regulation and Hypertension
- BRCA gene mutations in cancer
- Neuroblastoma Research and Treatments
- Hormonal and reproductive studies
- Parathyroid Disorders and Treatments
- Meningioma and schwannoma management
- Cancer-related Molecular Pathways
- Optical Imaging and Spectroscopy Techniques
- Infrared Thermography in Medicine
- Lung Cancer Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Eating Disorders and Behaviors
- Genetic factors in colorectal cancer
- Ovarian function and disorders
- Cancer, Hypoxia, and Metabolism
- Electrolyte and hormonal disorders
Hospital Clínic de Barcelona
2014-2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2001-2022
Universitat de Barcelona
2011-2022
Centro de Investigación Biomédica en Red de Salud Mental
2022
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2017-2021
Instituto de Salud Carlos III
2021
Hospital Universitario Doctor Peset
2020
Fundació Clínic per a la Recerca Biomèdica
2018
Hospital Universitari de Vic
2000-2017
Vall d'Hebron Hospital Universitari
2015
Objective: To determine the role of B19 parvovirus in red cell aplasia patients infected with human immunodeficiency virus type 1 (HIV-1). Design: Uncontrolled clinical trial, assay serum, peripheral blood cells, and bone marrow for using DNA hybridization immunocytochemistry techniques; these assays were then correlated findings, results immunoassays antivirus antibodies, immunoglobulin (Ig) therapy. Setting: Government medical referral center, university private hospitals. Patients: Seven...
OBJECTIVE: To undertake a multicentre epidemiological study reflecting acromegaly in Spain. DESIGN: Voluntary reporting of data on patients with to an online database, by the managing physician. METHODS: Data demographics, diagnosis, estimated date initial symptoms and pituitary imaging, visual fields, GH IGF-I concentrations (requested locally), medical, radiotherapy neurosurgical treatments, morbidity mortality were collected. RESULTS: included for 1219 (60.8% women) mean age at diagnosis...
Although thyroid cancer usually has an excellent prognosis, few therapeutic options are available in the refractory setting. Based on recent results of phase II studies with tyrosine kinase inhibitors, we designed a retrospective analysis patients metastatic treated sorafenib seven Spanish referral centers. Consecutive progressive (papillary, follicular, medullary, and anaplastic) not suitable for curative surgery, radioactive-iodine therapy, or radiotherapy were 400 mg twice day. The...
Transsphenoidal surgery is considered first-line therapy for acromegaly; however, there often a need adjunctive therapy. Somatostatin analogs (SSA) have greatly improved the effectiveness of medical treatment, but one third patients are resistant.The aim was to evaluate whether magnetic resonance imaging (MRI) signal could predict long-term response SSA in with active acromegaly after neurosurgery.Sixty-two who were acromegalic included this retrospective study. Remaining pituitary tumor...
Most cases of familial isolated pituitary adenomas with mutated aryl hydrocarbon receptor-interacting protein (AIP:HGNC:358) gene develop somatotropinomas. They are characterised by an aggressive clinical phenotype including early age at diagnosis, large tumours and frequent invasiveness. There is little information on AIP mutations' prevalence in somatotropinomas poor response to somatostatin analogue treatment. The aim this study was investigate the mutations non-familial conventional...
Ramos-Casals, Manuel M.D.; García-Carrasco, Mario M.D., Ph.D.; Cervera, Ricard Gaya, Joan Halperin, Irene Ubieto, Aymamí, Ana Morlà, Rosa M. Font, Josep Ingelmo, Miguel Ph.D. Author Information
The deletion of exon 3 in the GH receptor (GHR) has been associated with a different biochemical picture and response to therapy acromegaly.The aim study was determine whether or not GHR genotype influences efficacy pegvisomant treatment.A cross-sectional conducted six Spanish university hospitals.Forty-four acromegalic patients active disease resistance somatostatin analogs participated study.The prevalence full-length 3-deleted homozygous heterozygous genotypes 41, 2, 57%, respectively....
Context Pegvisomant is an effective treatment for somatostatin analogue-resistant acromegaly, but the determinants defining response to this are largely unknown. Objective To investigate efficacy of pegvisomant in resistant acromegalic patients (e.g. serum IGF1 at least 1.25×upper normal limit) a clinical setting and factors conditioning response. Design A retrospective cross-sectional study performed six Spanish University hospitals from 2004 2007. Patients Forty-four (61.4% female, mean...
Data on the prevalence of benign and malignant nodular thyroid disease in patients with acromegaly is a matter debate. In last decade an increasing incidence cancer has been reported. The aim this study was to evaluate goiter, nodules large series cross-sectional control group. Six Spanish university hospitals participated. One hundred twenty three (50% men; mean age 59±13 years; duration 6.7±7.2 years) 50 controls (51% males, 58±15 were studied. All participants underwent ultrasound fine...
The in vivo optical and hemodynamic properties of the healthy (n = 22) pathological 2) human thyroid tissue were measured non-invasively using a custom time-resolved spectroscopy (TRS) diffuse correlation (DCS) system. Medical ultrasound was used to guide placement hand-held hybrid probe. TRS absorption reduced scattering coefficients (μa, μs′) at three wavelengths (690, 785 830 nm) derive total hemoglobin concentration (THC) oxygen saturation (StO2). DCS microvascular blood flow index...
To determine if renal functional alterations in diabetes mellitus could be related to disturbances of vasoactive systems, plasma flow (RPF), glomerular filtration rate (GFR), PRA (basal and stimulated), catecholamine levels, urinary excretion prostaglandin E2 (PGE2), 6-keto- PGFia, kallikrein were determined 21 patients with insulin-dependent (IDDM) short duration 15 normal subjects. In 7 additional IDDM 4 subjects, the effect lysine acetylsalicylate (LAS; 450 mg, iv) on GFR RPF was studied....
An increasing number of transgender minors are seeking help during the development their gender identity and transitioning. Understanding characteristics impact transitioning on mental health would be in protocols to offer a better assistance this population. The aim study was examine socio-demographic clinical data related identity, persistence who were seen at Gender Identity Unit (GID) Catalonia, Spain. All underage applicants requested specialized GID from 1999 until 2016 retrospectively...