A5034758609- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Fungal and yeast genetics research
- Cancer Immunotherapy and Biomarkers
- RNA and protein synthesis mechanisms
- Immune cells in cancer
- Neuroendocrine Tumor Research Advances
- Protein purification and stability
- Transgenic Plants and Applications
- Advanced Proteomics Techniques and Applications
- Galectins and Cancer Biology
- Abdominal vascular conditions and treatments
- Renal cell carcinoma treatment
- Phagocytosis and Immune Regulation
Hospital del Mar Research Institute
2016-2019
Hospital Del Mar
2017-2019
Institut d'Investigació Biomédica de Bellvitge
2018
Municipal Institute for Medical Research
2017-2018
Universitat de València
2014
Pancreatic ductal adenocarcinoma (PDA) remains one of the most lethal tumor types, with extremely low survival rates due to late diagnosis and resistance standard therapies. A more comprehensive understanding complexity PDA pathobiology, especially role microenvironment in disease progression, should pave way for therapies improve patient response rates. In this study, we identify galectin-1 (Gal1), a glycan-binding protein that is highly overexpressed stroma, as major driver pancreatic...
Abstract Background Protein phosphatase 2A (PP2A) is a family of conserved serine/threonine phosphatases involved in several essential aspects cell growth and proliferation. PP2ACdc55 has been extensively related to cycle events budding yeast; however, few substrates have identified. Here, we performed quantitative mass spectrometry approach reveal new PP2A-related processes mitotic arrested cells. Results We identified 62 statistically significant mainly actin-cytoskeleton organization. In...
// Neus Martínez-Bosch 1 , Pedro Enrique Guerrero Mireia Moreno Anabel José 2, 3 Mar Iglesias 4 Jessica Munné-Collado Héctor Anta 1, 5 Joan Gibert Carlos Alberto Orozco Judith Vinaixa Cristina Fillat Francesc Viñals 6 Pilar Navarro Hospital del Medical Research Institute (IMIM), Barcelona, Spain 2 Biomedical August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red Enfermedades Raras (CIBERER), Pathology Service, Mar, for in Biomedicine (IRB Barcelona), Catalan of...
Pancreatic ductal adenocarcinoma (PDA), the most frequent type of pancreatic cancer, is one main unfinished businesses in biomedical and clinical fields, with still discouraging 5 year survival rates poor therapy efficiency. PDA abundant desmoplasia has for long played lead mechanisms involved drug performance, being source cytokines chemokines orchestrating rapid silent tumor progression guilty isolating cells into a extense fibrotic reaction resulting inefficient delivery. However, since...