A5070762092- GaN-based semiconductor devices and materials
- Particle accelerators and beam dynamics
- Coastal wetland ecosystem dynamics
- Impact of Light on Environment and Health
- Plant Stress Responses and Tolerance
- Plant responses to water stress
- Physics of Superconductivity and Magnetism
- Particle Accelerators and Free-Electron Lasers
- RNA modifications and cancer
- Metal and Thin Film Mechanics
- Circadian rhythm and melatonin
- Thin-Film Transistor Technologies
- Superconducting Materials and Applications
- Cancer-related molecular mechanisms research
- Color Science and Applications
- Recycling and Waste Management Techniques
- Microplastics and Plastic Pollution
- RNA Research and Splicing
- Epigenetics and DNA Methylation
- Gas Sensing Nanomaterials and Sensors
- Ocular and Laser Science Research
- Cancer-related Molecular Pathways
- Ga2O3 and related materials
- Topological Materials and Phenomena
- MicroRNA in disease regulation
State Key Laboratory of Nuclear Physics and Technology
2014-2025
Peking University
2014-2025
Northwest A&F University
2022-2025
Nankai University
2025
Institute of Oceanology
2015-2024
Binzhou University
2008-2024
Binzhou Medical University
2013-2024
Chinese Academy of Sciences
2015-2024
South China Sea Institute Of Oceanology
2015-2024
China Electric Power Research Institute
2021-2024
More and more evidences demonstrate that the long non-coding RNAs (lncRNAs) play many key roles in diverse biological processes. There is a critical need to annotate functions of increasing available lncRNAs. In this article, we try apply global network-based strategy tackle issue for first time. We develop bi-colored network based function predictor, RNA predictor ('lnc-GFP'), predict probable lncRNAs at large scale by integrating gene expression data protein interaction data. The...
Radiotherapy plays a vital role in cancer therapy. However, the hypoxic microenvironment of tumors greatly limits effectiveness, thus it is crucial to develop simple, efficient, and safe radiosensitizer reverse hypoxia ameliorate efficacy radiotherapy. Inspired by structure canonical nanodrug Abraxane, herein, native HSA-modified CaO
Nb3Sn has a superconducting transition temperature of 18.1 K and superheating magnetic field 420 mT, making it one the most promising materials for radiofrequency (SRF) cavities. The surface roughness reduction mechanical stability films are two important issues to improve cavity RF performance reliability in application conduction-cooling accelerators. This paper presents studies on prepared by tin vapor diffusion method proves advantages buffered electropolishing (BEP) as pre-polishing...
Background/Objectives: Paclitaxel (PTX) is a potent anticancer drug that poorly soluble in water. To enhance its delivery efficiency aqueous environments, amphiphilic polymer micelles are often used as nanocarriers for PTX clinical settings. However, the hydrophilic segments on surface of these may possess potential immunogenicity, posing risks applications. address this issue, nanomicelles based human serum albumin (HSA)–hydrophobic conjugates constructed via site-specific situ...
Shift workers are mostly suffered from the disruption of circadian rhythm and health problems. In this study, we designed proper light environment to maintain stable rhythm, cognitive performance, mood status shift workers. We used five-channel light-emitting diodes build up dynamic daylight-like environment. The illuminance, correlated color temperature, action factor were tunable in ranges 226 678 lx, 2680 7314 K, 0.32 0.96 throughout day (5:30 19:40). During nighttime, these parameters...
Abstract Mammalian genomes contain tens of thousands long non-coding RNAs (lncRNAs) that have been implicated in diverse biological processes. However, the lncRNA transcriptomes most mammalian species not established, limiting evolutionary annotation these novel transcripts. Based on RNA sequencing data from six tissues nine species, we built comprehensive catalogs (4,142–42,558 lncRNAs) covering major species. Compared to protein- coding RNAs, expression lncRNAs exhibits striking lineage...
Scope Maternal consumption of a high‐fat diet (HFD) during pregnancy increases the risk behavioral problems. Folate plays an important role in neuroplasticity and preservation neuronal integrity. This study aims at determining influence diets supplemented with folate on offspring behavior, mechanisms involved. Methods results Female mice were fed control diet, HFD, folate, or HFD for 5 weeks before mating. Open field task elevated plus maze are used to evaluate behaviors. Results showed that...
Nb3Sn-coating experiments on samples and single-cell cavities were conducted at Peking University (PKU) to understand the Nb3Sn growth process using vapor diffusion method. The evaporation of tin chloride used in was simulated experimentally analyzed. results show that nucleation is generally uniform, atomic ratios Nb/O Sn/O found be 1:2 within 10 nm surface nucleated samples. Three sources distributed along cavity axis obtain a uniform grain size surface, content 25~26% achieved....
Abstract Trench defects in multi‐quantum wells (MQWs) have been considered as flawed structures that severely degraded the internal quantum efficiency (IQE) of light‐emitting diodes (LEDs) past. In this research, trench are innovatively utilized to enhance red InGaN LEDs. Specifically, dual‐color MQWs applied modulate defects. The upper MQWs, grown on top green with a high density defects, exhibit significant wavelength redshift 68 nm and ≈ 6‐fold luminescence enhancement compared those...
Abstract Background The interaction between the karyoplast and cytoplast plays an important role in efficiency of somatic cell nuclear transfer (SCNT), but underlying mechanism remains unclear. It is generally accepted that embryos, reprogramming gene expression induced by epigenetic mechanisms does not involve modifications DNA sequences. In cattle, oocytes with various mitochondrial (mtDNA) haplotypes usually have different ATP content can further affect vitro production embryos. As mtDNA...
Mesenchymal stem cells (MSCs) have been isolated from many sources, including adults and fetuses. Previous studies demonstrated that, compared with their adult counterpart, fetal MSCs several remarkable advantages may be a better resource for clinical applications. In this study, we successfully rapidly proliferating cell population limb bud of aborted fetus termed them "human bud–derived mesenchymal cells" (hLB-MSCs). Characteristics morphology, phenotype, cycle, differentiation properties...