A5063270457- Pharmaceutical Practices and Patient Outcomes
- Heart Failure Treatment and Management
- Intensive Care Unit Cognitive Disorders
- Patient Safety and Medication Errors
- Innovations in Medical Education
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Medical Education and Admissions
- Case Reports on Hematomas
- Electrolyte and hormonal disorders
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
- Anesthesia and Neurotoxicity Research
- Respiratory Support and Mechanisms
- Potassium and Related Disorders
- Health Sciences Research and Education
- Cardiovascular Function and Risk Factors
- Sepsis Diagnosis and Treatment
- Pharmaceutical Economics and Policy
- Cardiac pacing and defibrillation studies
University of Maryland, Baltimore
2015-2025
University of Kentucky HealthCare
2018
University of Maryland Medical Center
2013-2017
Indianapolis Zoo
2016
American College of Clinical Pharmacy
2016
University of North Carolina at Pembroke
2016
University of Pittsburgh Medical Center
2012
University of Pittsburgh
2010
To provide ICU clinicians with evidence-based guidance on safe medication use practices for the critically ill.PubMed, Cochrane Database of Systematic Reviews, Central Register Controlled Trials, CINAHL, Scopus, and ISI Web Science relevant material to December 2015.Based three key components: 1) environment patients, 2) process, 3) patient safety surveillance system. The committee collectively developed Population, Intervention, Comparator, Outcome questions quality evidence statements...
Medication errors are common upon hospital admission. Clinical pharmacist involvement in medication reconciliation is effective identifying and rectifying errors. However, data lacking on the economic impact, time requirements, severity of resolved by clinical pharmacists.To determine incidence unintended admission discrepancies pharmacists. Secondary objectives were to type discrepancies, potential severity, proximal cause, impact this pharmacy program.This was a single-center, prospective,...
To compare safety and clinical outcomes of prolonged infusions with standard-dose (≤0.7 μg/kg/h) dexmedetomidine (SDD) or high-dose (>0.7 (HDD) to propofol in critically ill trauma patients.This was a retrospective review 127 adult mechanically ventilated patients between 2008 2009, who received propofol, SDD, HDD for >24 hours. Primary were significant changes blood pressure heart rate. Secondary included hospital intensive care unit (ICU) length stay (LOS), ventilator time, any concomitant...
To determine the point prevalence of drug-induced hypotension episodes in critically ill patients, to assess resulting from error, and describe how are treated.Multicenter observational, 24-hour snapshot study.Forty-seven ICUs 27 institutions located United States, Canada, Singapore.A total 688 ICU patients were evaluated.None.Patients included study if they had an episode 24 hours prior clinical pharmacists' evaluation. The definition for a hypotensive is either systolic blood pressure less...
In patients with traumatic brain injury (TBI), optimizing sedation is challenging because maintaining a clinical examination important in being able to detect neurological deterioration. Propofol (PROP) frequently used as sedative TBI since it has been shown reduce the cerebral metabolic rate, but may lead PROP-related infusion syndrome and hemodynamic compromise. Dexmedetomidine (DEX) that produces minimal respiratory depression opioid-sparing effects. The purpose of this study was...
To assess the efficacy and safety of intravenous (IV) chlorothiazide versus oral metolazone when added to loop diuretics in patients with acute decompensated heart failure (ADHF) diuretic resistance.Retrospective cohort study.Large urban academic medical center.Adults admitted ADHF between 2005 2015 who had resistance, defined as administration IV furosemide at a dose 160 mg/day or higher (or an equivalent bumetanide), during hospitalization, then received least one (88 patients) (89 augment...
Purpose To assess the clinical impact of a vancomycin dosing protocol and monitoring tool on initial dose, interval, trough concentrations in adult medicine patients. Methods This was retrospective chart review patients who received at least one dose were admitted during pre-implementation period, February 1 to April 2009, or post-implementation June October 31, 2009. All outcomes for group compared those group. The primary frequency appropriate interval. secondary included concentrations,...
Journal Article Accepted manuscript Incorporating project management into the profession of pharmacy Get access Lara K Ellinger, PharmD, BCPS, BCPS Department Quality and Patient Safety, Northwestern Memorial HealthCare, Chicago, IL, USA Corresponding author: laelling@nm.org Search for other works by this author on: Oxford Academic Google Scholar Sandeep Devabhakthuni, BCCP, BCCP Pharmacy Practice Science, University Maryland School Pharmacy, Baltimore, MD, Becky S Linn, Wyoming Fort Collins...
Performing lipid testing after statin initiation is recommended to monitor response. Inadequate response may indicate non-adherence, which associated with an increased risk of cardiovascular events and costs. Group-based trajectory modeling approach establish probabilistic developmental trajectories adherence, differentiating individuals by their distinct longitudinal medication-taking behaviors. We examined whether adherence among enrolled in a Medicare fee-for-service plan the USA. A...
Patients living with HIV (PLWH) are predisposed to atherosclerotic cardiovascular disease (ASCVD), resulting in concomitant antiretroviral and statin use. A prescribing gap for PLWH has been reported, but appropriateness of selection dosing (ASD) not described.This is a comparative, retrospective study reviewing ASD vs. uninfected patients at two outpatient clinics within an academic medical centre. Adults > 21 years old indicated therapy were included. The primary outcome was percentage...
Medication errors (MEs) and adverse drug events (ADEs) are a common significant concern in the ICU since they represent leading cause of iatrogenic critically ill population. MEs occur more frequently with greater likelihood harm patients compared non-ICU patients. can lead to ADEs associated deleterious outcomes enormous economic burden on healthcare system. An ideal patient safety culture an setting should incorporate multiple ME prevention strategies at all phases medication use process....
Abstract Purpose The primary objective was to evaluate the impact of an analgosedation protocol in a cardiac intensive care unit (CICU) on daily doses and costs analgesic, sedative, antipsychotic medications. Methods We conducted single-center quasi-experimental study 363 mechanically ventilated patients admitted our CICU from March 1, 2011, April 13, 2013. On 2012, implemented. Patients pre-implementation group were managed at cardiologist’s discretion, which consisted continuous...