Courtney Diamond
A5076306953- Traumatic Brain Injury Research
- Global Cancer Incidence and Screening
- Traumatic Brain Injury and Neurovascular Disturbances
- Colorectal Cancer Screening and Detection
- BRCA gene mutations in cancer
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Electronic Health Records Systems
- Innovations in Medical Education
- Dental Health and Care Utilization
- Topic Modeling
- Cognitive Functions and Memory
- Sport Psychology and Performance
- Esophageal and GI Pathology
- Cyclopropane Reaction Mechanisms
- Mobile Health and mHealth Applications
- Biomedical Text Mining and Ontologies
- Cardiac Arrest and Resuscitation
- HIV/AIDS drug development and treatment
- Tryptophan and brain disorders
- Patient Safety and Medication Errors
- Ethics in Clinical Research
- Synthesis and Catalytic Reactions
- Advanced MRI Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
Columbia University
2024
Columbia University Irving Medical Center
2023
Massachusetts General Hospital
2021-2022
Harvard University
2021
Virginia Commonwealth University
2019
Boston University
2016
Abstract Background Patterns of cognitive impairment in former American football players are uncertain because objective neuropsychological data lacking. This study characterized the test performance college and professional players. Methods One hundred seventy male ( n =111 professional, =59 college; 45–74 years) completed a battery. Raw scores were converted to T -scores using age, sex, education-adjusted normative data. A -score ≤ 35 defined impairment. domain was impaired if 2+ fell...
Exposure to repetitive head impacts (RHI) in American football players can lead cognitive impairment and dementia due neurodegenerative disease, particularly chronic traumatic encephalopathy (CTE). The pathognomonic lesion of CTE consists perivascular aggregates hyper-phosphorylated tau neurons at the depths cortical sulci. However, it is unclear whether exposure RHI accelerates amyloid-β (Aβ) plaque formation increases risk for Alzheimer's disease (AD). Although Aβ neuritic plaques...
Importance Realizing the benefits of cancer screening requires testing eligible individuals and processes to ensure follow-up abnormal results. Objective To test interventions improve timely overdue breast, cervical, colorectal, lung Design, Setting, Participants Pragmatic, cluster randomized clinical trial conducted at 44 primary care practices within 3 health networks in US enrolling patients with least 1 result not yet followed up between August 24, 2020, December 13, 2021. Intervention...
Traumatic encephalopathy syndrome (TES) is defined as the clinical manifestation of neuropathological entity chronic traumatic (CTE). A core feature TES neurobehavioral dysregulation (NBD), a neuropsychiatric in repetitive head impact (RHI)-exposed individuals, characterized by poor regulation emotions/behavior. To discover biological correlates for NBD, we investigated association between biomarkers inflammation (interleukin (IL)-1β, IL-6, IL-8, IL-10, C-reactive protein (CRP), tumor...
Cancer screening and timely follow-up of abnormal results can reduce mortality. One barrier to is the failure identify results. While EHRs have coded for certain tests, cancer are often stored in free-text reports, which limit capabilities automated decision support. As part multilevel Follow-up Screening (mFOCUS) trial, we developed implemented a natural language processing (NLP) tool assist with real-time detection test (including mammograms, low-dose chest CT scans, Pap smears)...
Abstract Objectives To identify successful strategies for retention of participants in multiyear, community‐based randomized controlled trials (RCTs) aiming to reduce early childhood caries health disparities populations from diverse racial/ethnic backgrounds and across geographic settings. Methods Four RCTs conducted by the Early Childhood Caries Collaborating Centers (EC4), an initiative National Institute Dental Craniofacial Research, systematically collected information on success...
Importance Exposure to repetitive head impacts (RHI) is associated with increased risk for neurodegeneration. Accumulation of toxic proteins due impaired brain clearance suspected play a role. Objective To investigate whether perivascular space (PVS) volume lifetime exposure RHI in individuals at RHI-associated Design, Setting, and Participants This cross-sectional study was part the Diagnostics, Imaging, Genetics Network Study Evaluation Chronic Traumatic Encephalopathy (DIAGNOSE CTE)...
ABSTRACT Objectives To develop an automated natural language processing (NLP) method for extracting high-fidelity Barrett’s Esophagus (BE) endoscopic surveillance and treatment data from the electronic health record (EHR). Methods Patients who underwent BE-related endoscopies between 2016 2020 at a single medical center were randomly assigned to development or validation set. Those not aged 40 80 those without confirmed BE excluded. For each patient, free text pathology reports structured...
Abstract A series of thiourea derivatives bearing pendant hydroxyl groups was synthesized. These quadruply nucleophilic compounds underwent cyclization reactions with bromoacyl bromides, yielding two isomeric iminothiozolidinones. While the remote group in functionalized thioureas not directly involved cyclization, it allowed us to establish control over product formation through choice temperature and/or solvent. The new mode temperature‐dependent distribution different from classical...
Diagnostic codes for Barrett's esophagus (BE), a precursor to esophageal cancer, lack granularity and precision many research or clinical use cases. Laborious manual chart review is required extract key diagnostic phenotypes from BE pathology reports. We developed generalizable transformer-based method automate data extraction. Using reports Columbia University Irving Medical Center with gastroenterologist-annotated targets, we performed binary dysplasia classification as well granularized...