- Education Pedagogy and Practices
- Physical Education and Sports Studies
- Prostate Cancer Treatment and Research
- Physical Education and Gymnastics
- Education and Public Policy
- Prostate Cancer Diagnosis and Treatment
- Academic Research in Diverse Fields
- Business and Management Studies
- Science and Education Research
- Youth, Drugs, and Violence
- Renal cell carcinoma treatment
- Health Education and Validation
- Cancer-related molecular mechanisms research
- Healthcare during COVID-19 Pandemic
- Bladder and Urothelial Cancer Treatments
- Physical Education and Pedagogy
- Urologic and reproductive health conditions
- Genital Health and Disease
- Education during COVID-19 pandemic
- Education and Digital Technologies
- Cerebral Palsy and Movement Disorders
- Healthcare Regulation
- Educational Practices and Policies
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
Universidade Estadual do Ceará
2017-2024
Instituto do Câncer do Estado de São Paulo
2017-2022
Universidade de São Paulo
2011-2022
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2017-2022
Universidade Federal do Ceará
2014-2022
Dr. Euryclides Hospital de Jesus Zerbini
2018-2020
Hospital São Paulo
2018
University of Minho
2013-2017
Centro Universitário Católica de Quixadá
2015-2017
Altera (United States)
2017
PD-L1 is a glycoprotein from the family of T-cell co-stimulatory molecules that are constitutively expressed by macrophages. Aberrant expression observed in human cancers associated with inhibition tumor-directed immune response. There few reports literature evaluating association to prognosis specifically renal cell cancer clear type (RCC-CC). Immunohistochemistry using polyclonal antibody was performed on tissue microarray (TMA) contained 115 surgical specimens RCC-CC. Cases were...
The search for biomarkers to characterize prostate cancer aggressiveness has been the objective majority of researchers involved with most prevalent tumor in men.MiRNAs are important control many cellular functions and their deregulation is development progression.To find miRNAs differentially expressed relation prognostic factors biochemical recurrence we studied 53 surgical specimens from men who underwent radical prostatectomy, through a microarray analysis using platform (GeneChip® miRNA...
Partial nephrectomy is the standard treatment for renal tumors <7 cm, and trend toward minimally invasive surgery has increased. However, data that could support its use benefits are still lacking.We conducted a prospective, randomized controlled trial comparing surgical, functional oncologic outcomes in patients undergoing open partial (OPN) or laparoscopic (LPN). Randomization was 1:1 to OPN LPN of cm. The primary endpoint surgical complications up 90 days after surgery. Secondary were...
Clear cell renal carcinoma (ccRCC) is the third most common urological cancer in adults. Our aim to evaluate genes and miRNAs expression profiles involved with angiogenesis tumor characteristics ccRCC. The levels of miR-99a, 99b, 100; 199a; 106a; 106b; 29a; 29b; 29c; 126; 200a, 200b their respective target genes: mTOR, HIF1-α, VHL, PDGF, VEGF, VEGFR1 VEGFR2 were analyzed using qRT-PCR tissue samples from 56 patients Five benign utilized as control. related size, Fuhrman nuclear grade...
O presente artigo buscou compreender em qual grau o atual cenário de pandemia afetou envolvimento nas atividades aprendizagem por parte dos estudantes do ensino superior, devido às alterações formas contato entre e docentes no contexto acadêmico, e, também, a opção generalizada pelo remoto letivas. Participaram estudo 1.452 universitários brasileiros, matriculados primeiro último ano, frequentando cursos das três grandes áreas da CAPES: Ciências Exatas Tecnológicas, Vida Humanas....
CD44 is a transmembrane glycoprotein and regarded as potential marker in various tumors. The aim of our study was to analyze the expression standard form (CD44s) its isoforms localized prostate cancer (PCa), correlate these data with classical prognostic factors biochemical recurrence. Ninety-four surgical specimens were analyzed this study. levels CD44s all 9 variants by quantitative real time PCR (qRT-PCR). control group consisted 14 from patients benign prostatic hyperplasia. We...
5018 Background: The role of extended pelvic lymph node dissection (ePLND) in treating prostate cancer (PCa) patients remains controversial, mainly by the lack RCTs. Methods: Patients with D'Amico intermediate or high risk PCa, absence bone metastasis and no previous treatment were prospectively computer randomised to undergo limited PLND (1:1) during radical prostatectomy. Limited (lPLND) included obturator chain bilaterally; ePLND involved bilaterally chains: obturator, external-,...
To evaluate the length hospital stay and predictors of prolonged hospitalization after RRP performed in a high-surgical volume teaching institution, analyze rate unplanned visits to office, emergency care, readmissions perioperative complications rates.Retrospective analysis prospectively collected data standardized database for patients with localized prostate cancer undergoing our institution between January/2010 - January/2012. A logistic regression model including preoperative variables...
Penile cancer (PeC) carcinogenesis is not fully understood, and no biomarkers are reported in clinical practice. We aimed to investigate molecular signatures based on miRNA mRNA perform an integrative analysis identify drivers pathways for PeC development. Affymetrix microarray was used differentially expressed miRNAs (DEmiRs) comparing 11 tumoral tissues (TT) paired with non-neoplastic (NNT) further validation independent cohort (n = 13). also investigated the expression of 83 genes total...
Purpose: Single positive core in a prostate biopsy is usually associated with indolent cancer (PCa) and one of the active surveillance (AS) inclusion criteria.We investigated whether single PCa at could define an archetype low-risk disease.Materials Methods: A total 1320 consecutive patients were enrolled.Among them, 249 followed up, clinical pathological parameters influencing prognosis analyzed.Results: Out patients, 172 (69.0%) had findings ≥ pT2c 87 (34.9%) undergraded Gleason Score (GS)...
Penile cancer (PeC) is a rare disease, and no prognostic biomarkers have been adopted in clinical practice yet. The objective of the present study was to identify differentially expressed miRNAs (DEmiRs) genes (DEGs) as potential for lymph node metastasis other factors PeC. Tumor samples were prospectively obtained from 24 patients with squamous cell carcinoma penis. miRNA microarray analysis performed comparing tumors inguinal metastatic localized results validated by qRT-PCR. Eighty-three...
A psicomotricidade define-se como a relação dos sujeitos movimento, levando em consideração os aspectos relacionais, afetivos e cognitivos. O desenvolvimento psicomotor contribui para evitar dificuldades de aprendizagem reeduca o tônus, postura, direção, lateralidade, ritmo etc. objetivo deste estudo foi avaliar conhecimento professores Educação Física da Básica Fortaleza-CE sobre psicomotor. Trata-se uma metodologia descritiva exploratória, abordagem quali-quantitativa. amostra contou com...
To generate and present survey results on important issues relevant to treatment follow-up of localized locally advanced, high-risk prostate cancer (PCa) focusing developing countries.A panel 99 PCa experts developed more than 300 questions which 67 concern the main areas interest this article: in countries. A larger international multidisciplinary voted these create recommendations for limited resources discussed article.The publicly but anonymously predefined questions. Each question was...
Tendo como referências as políticas de direitos humanos e fundamentais, a Constituição 1988 LDB 1996, discussão da Política Nacional Formação Professores visa propor caminhos para superar perspectiva reducionista formação centrada nos processos ensino aprendizagem ocupar-se também das relações humanas. O estudo teve objetivo analisar o papel do Estágio Curricular Supervisionado (ECS) Residência Pedagógica (RP) possíveis espaços docente crítico-reflexiva. Em um caso abordagem qualitativa,...
To evaluate the relation between serum total testosterone (TT) and prostate cancer (PCa) grade effect of race demographic characteristics on such association.We analyzed 695 patients undergoing radical prostatectomy (RP), whom 423 had TT collected. Patients were classified as having hypogonadism or eugonadism based two thresholds testosterone: threshold 1 (300 ng/dL) 2 (250 ng/dL). We evaluated levels a Gleason score (GS) ≥ 7 in RP specimens. Outcomes using univariate multivariate analyses,...
5085 Background: Patients (pts) with high-risk localized prostate cancer (HRLPC) have a significant risk of disease recurrence and metastasis after radical prostatectomy (RP). Neoadjuvant therapy remains investigational but there may be role for the next-generation androgen signaling inhibitors. We sought to evaluate pathologic imaging response intense neoadjuvant approach. Methods: This is phase II investigator-initiated randomized trial 3-month goserelin (androgen deprivation therapy, ADT)...
Apontar os principais fatores associado ao desempenho acadêmico, desde a Educação Básica até o Ensino Superior, pode contribuir na construção e inovação de políticas públicas educacionais. Dessa forma, estudo teve como objetivo associar dos estudantes cursos licenciatura em Física no Exame Nacional Desempenho Estudantes (Enade) com as variáveis referentes à escolaridade estudantil. Trata-se um descritivo, exploratório transversal. Participaram 15.400 (26,52 ± 6,43 anos idade) do curso...
INTRODUCTION. Physical Education in school enables contextualization of physical exercisewith themes related to student learning objectives for sports, as well socio-affective andcognitive aspects. However, this last point, there is a lack reference matrix large scalecognitive evaluation which allows identification students’ knowledge relation the contentof Education. Therefore, study aims develop and validate matrix(model) scale cognitive education school. METHOD. The matrixwas developed...
You have accessJournal of UrologyProstate Cancer: Localized VI1 Apr 2015PD43-06 EXTENDED VS LIMITED PELVIC LYMPHADENECTOMY DURING RADICAL PROSTATECTOMY FOR INTERMEDIATE- AND HIGH-RISK PROSTATE CANCER: A PROSPECTIVE RANDOMIZED TRIAL. Jean F.P. Lestingi, Jose Pontes Jr, Leonardo L. Borges, Juliana Ravanini, Giuliano B. Guglielmetti, Mauricio D. Cordeiro, Rafael F. Coelho, and William C. Nahas LestingiJean Lestingi , JrJose Jr BorgesLeonardo Borges RavaniniJuliana Ravanini GuglielmettiGiuliano...
You have accessJournal of UrologyProstate Cancer: Localized1 Apr 20111104 EARLY RESULTS ON A PROSPECTIVE RANDOMIZED TRIAL: ROBOTIC-ASSISTED LAPAROSCOPIC PROSTATECTOMY (RALP) VERSUS RETROPUBIC RADICAL (RRP) STUDY Carlo Camargo Passerotti, Alberto Azoubel Antunes, Marcelo Takeo Rufato Okano, Jose Arnaldo Shiomi da Cruz, Adriano Joao Nesrallah, José Pontes, Marcos Freire, Rodrigo Pessoa, Francisco Dall'Oglio, and Miguel Srougi PasserottiCarlo Passerotti Sao Paulo, Brazil More articles by this...
Artigos completos submetidos ao I SAFS UniCatólica – “I Simpósio de Atividade Física relacionada à Saúde da UniCatólica” realizado nos dias 10, 11 e 12 novembro 2015 no Centro Universitário Católica Quixadá, em Ceará-Brasil