Dilek Doğruel

ORCID: 0000-0003-2100-0301
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Research Areas
  • Inflammasome and immune disorders
  • Food Allergy and Anaphylaxis Research
  • Asthma and respiratory diseases
  • Vasculitis and related conditions
  • Immunodeficiency and Autoimmune Disorders
  • Autoimmune and Inflammatory Disorders Research
  • Tracheal and airway disorders
  • Diabetes and associated disorders
  • Systemic Lupus Erythematosus Research
  • Neonatal Respiratory Health Research
  • Cystic Fibrosis Research Advances
  • Renal Diseases and Glomerulopathies
  • Pediatric health and respiratory diseases
  • Adolescent and Pediatric Healthcare
  • Allergic Rhinitis and Sensitization
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Congenital Diaphragmatic Hernia Studies
  • Celiac Disease Research and Management
  • Diabetes Management and Research
  • COVID-19 Clinical Research Studies
  • Respiratory and Cough-Related Research
  • Oral and Craniofacial Lesions
  • Eosinophilic Esophagitis
  • Dermatology and Skin Diseases
  • Drug-Induced Adverse Reactions

Sağlık Bilimleri Üniversitesi
2024

University of Health Science
2024

Gaziantep Children's Hospital
2024

Adana Numune Eğitim ve Araştırma Hastanesi
2023

Cukurova University
2011-2022

Başkent University
2016

Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
2016

Abstract Objectives The COVID-19 pandemic is a global health problem with high morbidity and mortality. This study aimed to investigate patients who were diagnosed type 1 diabetes during the evaluate effect of on clinical findings these by comparing them from year prior. Methods Patients mellitus between 2019 2021 separated into two groups: prepandemic those pandemic. Results number newly cases increased 46 in period 74 period. diabetic ketoacidosis (DKA) clinic 58.7 91.9%. We found that...

10.1515/jpem-2021-0287 article EN Journal of Pediatric Endocrinology and Metabolism 2021-07-22

Objectives: Henoch Schönlein Purpura (HSP) is the most common systemic vasculitis in childhood. We aimed to evaluate clinical features, seasonal variation, treatment outcomes and possible predicting factors related outcome among a large cohort of pediatric HSP patients. Methods: conducted medical record review study between July 2016 January 2019 evaluated manifestations potential risk for severe gastrointestinal (GI) involvement, biopsy-proven nephritis relapses. Results: The included 420...

10.1080/14397595.2019.1687074 article EN Modern Rheumatology 2019-10-30

Although it is known that there has been an increase in asthma and allergic diseases among school-aged children, results vary between countries. The aim of this study was to examine trends the prevalence these city Adana (south Turkey) over last 20 years based on 3 cross-sectional studies.Three surveys were performed 10 apart south Turkey. Here, we compare conducted children ages 6 14 from 1994, 2004, 2014. participants randomly chosen attending participating primary schools Adana....

10.1159/000477726 article EN International Archives of Allergy and Immunology 2017-01-01

Objectives: Henoch Schönlein Purpura (HSP) is the most common systemic vasculitis of childhood and often has a self-limiting course. We aimed to study whether practical laboratory parameters at diagnosis predict disease course including recurrence nephritis in addition severe gastrointestinal involvement children with HSP. Methods: This retrospective cohort included 214 HSP patients, 43.5% (n = 93) female 56.5% =121) male, who were diagnosed our department. Laboratory before treatment,...

10.1080/00325481.2019.1609814 article EN Postgraduate Medicine 2019-04-25

<b><i>Background:</i></b> Although food allergies (FAs) occur most commonly during the 1st year of life, there is limited information available regarding epidemiology FAs. In this study, we investigated incidence FA and associated risk factors life in southeast Turkey. <b><i>Methods:</i></b> This study a prospective evaluation 1,377 infants born at Balcalı Hospital (Çukurova University) includes four routine follow-up assessments until age 1...

10.1159/000444639 article EN International Archives of Allergy and Immunology 2016-01-01

Deficiency of adenosine deaminase 2 (DADA2) is a rare autoinflammatory disease that was firstly described in patients with early-onset strokes, livedo reticularis, and periodic fever resembling polyarteritis nodosa. In reported case series, researchers highly variable manifestations, including autoimmunity, immunodeficiency, hepatosplenomegaly, pancytopenia, ichthyosiform rash, arthritis, DADA2. A thirteen-year-old female patient who born to consanguineous parents admitted our hospital...

10.1542/peds.2018-0948 article EN PEDIATRICS 2018-10-30

<b><i>Objective:</i></b> Systemic administration of magnesium sulfate (MgSO<sub>4</sub>) has been proposed as a treatment for pediatric patients with acute asthma. However, previous trials show mixed results and uncertain evidence benefit. The aim the study was to ascertain whether intravenous (IV) MgSO<sub>4</sub> improves lung function parameters in children <b><i>Methods:</i></b> This prospective clinical trial. All...

10.1159/000506595 article EN cc-by-nc Medical Principles and Practice 2020-01-01

There have been some significant changes regarding healthcare utilization during the COVID-19 pandemic. Majority of reports about impact pandemic on diabetes care are from first wave We aim to evaluate potential effects severity diabetic ketoacidosis (DKA) and new onset Type 1 presenting with DKA, also children DKA acute infection. This is a retrospective multi-center study among 997 adolescents type who were admitted 27 pediatric intensive units in Turkey between year pre-pandemic year. The...

10.3389/fped.2022.926013 article EN cc-by Frontiers in Pediatrics 2022-06-29

Henoch-Schönlein purpura (HSP) is characterized by non-thrombocytopenic palpable purpura, abdominal pain, and arthralgia/arthritis. We aimed to describe the clinical presentations of children with HSP in a single center compare prevalence each manifestations between patients MEFV variants, particularly exon 10 those without.This cohort retrospectively included 144 (59 females, 85 males) without Familial Mediterranean Fever (FMF) symptoms followed for at least 6 months. utilized gene...

10.1080/00325481.2019.1552479 article EN Postgraduate Medicine 2018-12-05

<b><i>Background:</i></b> Although food allergy (FA) is often a transient condition during childhood, when and in whom FA will resolve can be affected by many factors. In this study, we analyzed the data at 5 years on 33 children diagnosed with ADAPAR (Adana Pediatric Allergy Research) birth cohort study southern Turkey. <b><i>Methods:</i></b> Thirty-three infants detected as having end of their first year were assessed every 6 months until age...

10.1159/000443831 article EN International Archives of Allergy and Immunology 2016-01-01

Abstract Objective Autosomal‐recessive hypophosphataemic rickets type 2 (ARHR2) is a rare disease that reported in survivors of generalized arterial calcification infancy (GACI). Design, Patients and Measurement The objective this study was to characterize multicenter paediatric cohort with ARHR2 due ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) deficiency diagnosis GACI or GACI‐related findings. clinical, biochemical genetic characteristics the patients were...

10.1111/cen.15028 article EN Clinical Endocrinology 2024-02-07

Familial Mediterranean fever (FMF) is the most common autoinflammatory disease and characterized by recurrent serositis episodes. We aimed to share our 20-year FMF experience, clarify a phenotype-genotype correlation, compare characteristics outcomes of pediatric patients over last 2 decades in this study.This medical record review study included 714 (340 females, 374 males), diagnosed Tel Hashomer diagnostic criteria between January 2009 2019 followed up department. Demographic...

10.1097/rhu.0000000000001146 article EN JCR Journal of Clinical Rheumatology 2019-11-06

Introduction Henoch Schönlein purpura is characterised by palpable purpura, abdominal pain, arthritis/arthralgia, often with a self-limiting course. Herein, we report patient recurrent and severe gastrointestinal involvement, successfully treated methotrexate. Case presentation A 12-year-old boy was admitted to our department pain arthralgia. Since complaints were severe, systemic steroids administered, tapering of dosage. recurred several times maelena during next two months. Colchicine...

10.1177/0036933018809816 article EN Scottish Medical Journal 2018-11-19

Morphological changes due to lung disease in patients with cystic fibrosis (CF) were evaluated using high resolution computed tomography (HRCT), and the HRCT scores obtained Bhalla scoring system correlated those clinical laboratory indicators.Medical records of 28 children CF who underwent chest CT Department Pediatric Allergy Immunology, Cukurova University Balcali Hospital between March 2011 January 2016 retrospectively reviewed. Demographic data physical examination, respiratory...

10.3904/kjim.2017.287 article EN cc-by-nc The Korean Journal of Internal Medicine 2018-07-06
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