Dominic Pérennou

ORCID: 0000-0003-2125-386X
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About
Contact & Profiles
Research Areas
  • Stroke Rehabilitation and Recovery
  • Spatial Neglect and Hemispheric Dysfunction
  • Cerebral Palsy and Movement Disorders
  • Musculoskeletal pain and rehabilitation
  • Botulinum Toxin and Related Neurological Disorders
  • Balance, Gait, and Falls Prevention
  • Ophthalmology and Eye Disorders
  • Acute Ischemic Stroke Management
  • Neurological disorders and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Motor Control and Adaptation
  • Vestibular and auditory disorders
  • Musculoskeletal Disorders and Rehabilitation
  • Neurobiology of Language and Bilingualism
  • Spatial Cognition and Navigation
  • Prosthetics and Rehabilitation Robotics
  • Visual perception and processing mechanisms
  • Peripheral Nerve Disorders
  • Parkinson's Disease and Spinal Disorders
  • Peripheral Artery Disease Management
  • Obstructive Sleep Apnea Research
  • Death, Funerary Practices, and Mourning
  • Scoliosis diagnosis and treatment
  • Lymphatic System and Diseases
  • Neurogenetic and Muscular Disorders Research

Centre Hospitalier Universitaire de Grenoble
2016-2025

Université Grenoble Alpes
2016-2025

Laboratoire de Psychologie et NeuroCognition
2016-2025

Centre National de la Recherche Scientifique
2016-2025

Université de Montpellier
2009-2025

Université Savoie Mont Blanc
2018-2024

New York Academy of Sciences
2023

John Wiley & Sons (Germany)
2023

Moss Landing Marine Laboratories
2023

Hudson Institute
2023

The lack of agreement regarding assessment methods is responsible for the variability in reported rate occurrence spatial neglect after stroke. aim this study was to assess sensitivity different tests right hemisphere stroke.Two hundred and six subacute stroke patients were given a test battery including preliminary anosognosia visual extinction, clinical gaze orientation personal neglect, paper pencil peripersonal space. Patients compared with previously control group. A subgroup (n=69)...

10.1136/jnnp.73.2.160 article EN Journal of Neurology Neurosurgery & Psychiatry 2002-07-28

Internal models serve sensory processing, sensorimotor integration and motor control. They could be a way to construct update sense of verticality, by combining vestibular somatosensory graviception. We tested this hypothesis investigating self-orientation relative gravity in 39 normal subjects with various losses showing either complete deafferentation trunk lower limbs (14 paraplegic patients after traumatic spinal cord injury) or gradient the degree hemibody loss (23 hemiplegic stroke)....

10.1093/brain/awq311 article EN Brain 2010-11-19

Abstract Stroke significantly impacts the quality of life. However, long-term cognitive evolution in stroke is poorly predictable at individual level. There an urgent need to better predict symptoms based on acute clinical neuroimaging data. Previous works have demonstrated a strong relationship between location white matter disconnections and symptoms. rendering entire space possible disconnection-deficit associations optimally surveyable will allow for systematic association brain...

10.1093/brain/awad013 article EN cc-by Brain 2023-03-16

Purpose: The lack of agreement regarding assessment methods is responsible for the variability in reported rate occurrence unilateral neglect (UN) after stroke. In addition, dissociations have been between performance on traditional paper-and-pencil tests and UN everyday life situations. Methods: this paper, we present validation studies a quantitative test battery UN, including tests, an personal neglect, extinction, anosognosia, behavioural assessment, Catherine Bergego Scale (CBS). was...

10.3233/rnn-2006-00351 article EN Restorative Neurology and Neuroscience 2006-01-01

Comparatively little research has been conducted on right neglect after left brain damage. The authors sought to assess contralateral in subacute hemisphere stroke patients using a comprehensive test battery validated large control group stroke.Seventy-eight were assessed. included preliminary assessment of anosognosia and visual extinction, clinical gaze orientation personal neglect, paper-and-pencil tests spatial the peripersonal space. Only nonverbal used.Drawing cancellation tasks...

10.1212/01.wnl.0000142967.60579.32 article EN Neurology 2004-11-09

Background and Purpose— Intensive physical therapy (PT) facilitates motor recovery when provided during a subacute stage after stroke. The efficiency of very early intensive PT has been less investigated. We aimed to investigate whether conducted within the first 2 weeks could aid control. Methods— This multicentre randomized controlled trial compared soft (20-min/d apart from respiratory needs) (idem+45 minutes exercises/day) initiated 72 hours hemispheric primary outcome was change in...

10.1161/strokeaha.116.014803 article EN Stroke 2016-12-23

To test the hypothesis that impaired body orientation with respect to gravity (lateropulsion) would play a key role in poststroke balance and gait disorders.Cohort study of 220 individuals consecutively admitted neurorehabilitation ward after first hemisphere stroke (DOBRAS cohort [Determinants Balance Recovery After Stroke] 2012-2018, ClinicalTrials.gov: NCT03203109), clinical data systematically collected at 1 month, then discharge. Primary outcomes were disorders, quantified by Postural...

10.1212/wnl.0000000000011152 article EN Neurology 2020-11-12

Background and Purpose— The Aphasic Depression Rating Scale (ADRS) was developed to detect measure depression in aphasic patients during the subacute stage of stroke. Methods— Six experts selected an initial sampling behavioral items from existing rating scales. Stroke (aphasic nonaphasic) were assessed with these by rehabilitation staff, Hamilton (HDRS) for nonaphasic only, a psychiatrist, staff Visual Analog Scales (VAS). A second item selection conducted after regression algorithm run...

10.1161/01.str.0000130591.95710.20 article EN Stroke 2004-05-18

In this paper we analyse the arguments for a strong association between spatial neglect and postural disorders attempt to better understand mechanisms which underlie that.We first provide general overview of available tools rational assessment control in clinical context. We then favour close relationship, although not necessarily causal, and: 1) body orientation with respect gravity (including verticality perception i.e. visual vertical, haptic vertical); 2) stabilisation base support; 3)...

10.3233/rnn-2006-00363 article EN Restorative Neurology and Neuroscience 2006-01-01

To test the hypothesis that lateropulsion is an entity expressing impaired body orientation with respect to gravity in relation a biased graviception and spatial neglect.Data from DOBRAS cohort (ClinicalTrials.gov: NCT03203109) were collected 30 days after first hemisphere stroke. Lateral tilt, pushing, resistance assessed Scale for Contraversive Pushing.Among 220 individuals, 72% upright 28% showed (tilters [14%] less severe than pushers [14%]). The 3 signs had very high factor loadings...

10.1212/wnl.0000000000011826 article EN Neurology 2021-03-15

There is an outstanding increased demand for recommendations in the rehabilitation field. Over 600 recommendation articles have been published last decade, primarily by groups of authors based on unclear criteria and only a few learned societies standardized methods. In 2007, French Society Physical Rehabilitation Medicine (SOFMER) methodology to establish physical medicine (PRM). This framework, which served publish 22 sets management recommendations, must be reworked meet new international...

10.1016/j.rehab.2025.101951 article EN cc-by Annals of Physical and Rehabilitation Medicine 2025-03-22

<h3>Background:</h3> Cobalamin C disease is the most common inborn error of cobalamin metabolism with an autosomal recessive mode inheritance and mutations within <i>MMACHC</i> gene. Clinical features, including systemic, haematological neurological abnormalities, usually occur in first year life. Adolescent adult onset presentations are rare. <h3>Methods:</h3> We report on clinical, molecular imaging features three patients aged 40, 42 years at last follow-up. examine these cases together...

10.1136/jnnp.2007.133025 article EN Journal of Neurology Neurosurgery & Psychiatry 2007-10-10

Objective. To compare 2 rehabilitation strategies to improve balance after stroke: (1) a multisensorial approach based on higher intensity of tasks and exercise during visual deprivation (2) conventional neurodevelopmentaltheory-based treatment (NDT) that used general for sensorimotor rehabilitation. Methods . This prospective, multicenter, randomized, parallel-group study measured outcomes with blinded assessors. Sixty-eight patients able walk without human assistance were entered from 3 15...

10.1177/1545968308315996 article EN Neurorehabilitation and neural repair 2008-05-16
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