A5023356144- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Per- and polyfluoroalkyl substances research
- Effects and risks of endocrine disrupting chemicals
- Energy and Environment Impacts
- Health, Environment, Cognitive Aging
- Fluoride Effects and Removal
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Pregnancy and Medication Impact
- Environmental Justice and Health Disparities
- Neuroscience of respiration and sleep
- Carcinogens and Genotoxicity Assessment
- Bone health and osteoporosis research
- Diet and metabolism studies
- Molecular Biology Techniques and Applications
- Genetic Associations and Epidemiology
- COVID-19 and healthcare impacts
- Nutrition, Genetics, and Disease
- Infection Control and Ventilation
- Nutrition and Health in Aging
- Gestational Diabetes Research and Management
- Vitamin D Research Studies
- Atmospheric chemistry and aerosols
- Body Composition Measurement Techniques
MaineHealth
2023-2024
Tufts University
2024
Harvard University
2017-2023
Maine Medical Center
2022
Maine Medical Center Research Institute
2022
Harvard Pilgrim Health Care
2017-2019
Boston Children's Hospital
2016-2017
During the conduct of a cohort study intended to associations between mixed metal exposures and child health outcomes, we found that 78% 309 children aged 20-40 months evaluated in Munshiganj District Bangladesh had blood lead concentrations ≥5 µg/dL 27% ≥10 µg/dL. Environmental sources such as spices (e.g., turmeric, which has already faced recalls due high levels) may be potential route exposure. We conducted visits homes 28 randomly selected from among low concentration groups. visits,...
Background: Identifying factors that impair bone accrual during childhood is a critical step toward osteoporosis prevention. Exposure to per- and polyfluoroalkyl substances (PFASs) has been associated with lower mineral density, but data are limited, particularly in children. Methods: We studied 576 children Project Viva, Boston-area cohort of mother/child pairs recruited prenatally from 1999 2002. quantified plasma concentrations several PFASs measured areal density (aBMD) by dual-energy...
Reduced fetal growth is associated with perinatal and later morbidity. Prenatal exposure to environmental pollutants linked reduced at birth, but the impact of concomitant multiple unclear. The purpose this study was examine interactions between early pregnancy cigarette smoke, traffic pollution, select perfluoroalkyl substances (PFASs) on birth weight-for-gestational age (BW/GA). Among 1597 Project Viva mother-infant pairs, we assessed maternal smoking by questionnaire, pollution...
Occupational exposures to ultrafine particles in the plume generated during laser hair removal procedures, most commonly performed light based cosmetic procedure, have not been thoroughly characterized. Acute and chronic ambient associated with a number of negative respiratory cardiovascular health effects. Thus, aim this study was measure airborne concentrations diameter size range 10 nm 1 μm procedure rooms procedures. TSI Model 3007 Condensation Particle Counters were used quantify...
Background: Prenatal exposure to environmental chemicals may increase risk of childhood internalizing problems, but few studies have explored the potential for longer-term consequences such exposures. Objective: We evaluated associations between prenatal organochlorine and metal levels early adulthood symptoms, considering whether sociodemographic/nonchemical stressors modified these associations. Methods: Participants were 209 young adults, born (1993–1998) mothers residing in or near New...
Dual-energy x-ray absorptiometry reference data designate Black and non-Black categories, as higher BMD has been documented among youth. We examined associations of race, skin tone, genetic factors with bone mineral density (BMD).
PFAS may impair bone health, but effects of exposure assessed during pregnancy and the perimenopause-life stages marked by rapidly changing metabolism-on later life health are unknown.
There is limited research on associations of per- and polyfluoroalkyl substances (PFAS) with areal bone mineral density (aBMD) through adolescence whether bone-strengthening factors ameliorate effects. In the Project Viva cohort (
Background/Aim: Exposure to combinations of chemical neurotoxicants has not been well explored as a risk factor for mental health difficulties. We evaluated associations prenatal exposure mixtures organochlorines and metals with adolescent internalizing behaviors.Methods: Participants were 397 socioeconomically (32% household income <$20,000) racially (31% non-White) diverse children from prospective birth cohort recruited at (1993-1998) in New Bedford, Massachusetts. Organochlorines...
Introduction: Per- and polyfluoroalkyl substances (PFASs) are synthetic stain grease repellents that may persist in the environment humans. Data on metabolic effects among children exposed to PFASs prenatally or early life limited. Methods: We studied 665 mother/child pairs Project Viva, a Boston-area pre-birth cohort. quantified concentrations of perfluorooctane sulfonate (PFOS), perfluorohexane (PFHxS), perfluorooctanoate (PFOA), perfluorononanoate (PFNA), perfluorodecanoate (PFDeA)...
Background and Aim: Phthalates may adversely influence body composition by lowering anabolic hormones activating peroxisome-proliferator activated receptor gamma. However, data are limited in adolescence when mass distributions rapidly changing bone accrual is peaking. Also, the health impact of legacy phthalate replacements [e.g., di-2-ethylhexyl terephthalate (DEHTP)] has not been well studied. Methods: Among 578 children Project Viva cohort, we used linear regression to evaluate...
BACKGROUND AND AIM: Exposure to neurotoxicant metals, hypothesized alter dopaminergic function, have not been sufficiently explored as a risk factor for maternal depression. We evaluated the extent which early pregnancy blood levels of essential and non-essential metals were prospectively associated with depressive symptom trajectories from mid-pregnancy 7-years postpartum. METHODS: Participants 872 women in Project Viva, longitudinal Boston-area cohort recruited during (1999-2002). measured...
BACKGROUND AND AIM: The extent to which chemical exposures influence mental health has not been well characterized. We evaluated associations of anxiety and depressive disorder diagnoses with prenatal organochlorine metal exposures, considering effect modification by quality the home environment. METHODS: Participants were 172 adults (19-25 years), from a prospective cohort recruited at birth (1993-1998) in New Bedford, Massachusetts. Hexachlorobenzene, p,p'-dichlorobiphenyl dichloroethylene...