A5038973061- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Atrial Fibrillation Management and Outcomes
- Congenital Heart Disease Studies
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Coronary Artery Anomalies
- Non-Invasive Vital Sign Monitoring
- Ion channel regulation and function
- Cardiovascular and exercise physiology
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Blood Pressure and Hypertension Studies
- Neuroscience of respiration and sleep
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Pulmonary Hypertension Research and Treatments
- Kawasaki Disease and Coronary Complications
- Cardiovascular Function and Risk Factors
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Aortic Disease and Treatment Approaches
- Renal Transplantation Outcomes and Treatments
Hospital de Santa Marta
2016-2025
Universidade Nova de Lisboa
2022-2025
CUF Porto Hospital
2024
ERN GUARD-Heart
2024
Nova Medical (United States)
2024
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024
Centro De Medicina Veterinária Anjos De Assis
2024
Hospital de São José
2024
University of Lisbon
2012-2023
Centro Hospitalar de Lisboa Central
2012-2023
Summary Purpose: Postictal generalized EEG suppression (PGES) seems to be a pathophysiologic hallmark in ictal recordings of sudden unexpected death epilepsy (SUDEP). It has recently been suggested that presence and duration PGES might predictor SUDEP risk. Little is known about the etiology PGES. Methods: We conducted retrospective case–control study 50 people with convulsive seizures (CS) recorded on digital video–electroencephalography (EEG). One CS per individual was reviewed for by two...
Introduction: Vasovagal syncope is a prevalent condition marked by transient loss of consciousness due to abrupt decreases in systemic blood pressure and/or heart rate. Despite its clinical impact, the underlying haemodynamic mechanisms remain poorly defined, and data on age-related differences are limited sometimes contradictory. Objectives: This study aimed characterise adaptation patterns during head-up tilt (HUT) test adult (≥18 years) paediatric (<18 patients with recurrent reflex...
Background Arterial stiffness and cardiac autonomic function are crucial indicators of cardiovascular health. Acute exercise age impact these parameters, but research often focuses on specific activities, lacking ecological validity. Methods We examined the acute effects commercially available group fitness classes (indoor cycling, resistance training, combined exercise) arterial vagal-related heart rate variability (HRV) indices in twelve young middle-aged adults. Participants attended four...
Non-invasive autonomic evaluation has used fast Fourier transform (FFT) to assign a range of low (LF) and high frequencies (HF) as markers sympathetic parasympathetic influences, respectively. However, FFT cannot be applied brief transient phenomena, such those observed on performing tests where the acute changes cardiovascular signals (blood pressure heart rate) that represent first most important stage performance towards new state equilibrium occur. Wavelet analysis been proposed method...
Background: Catheter ablation (CA) is a well-established treatment for atrial fibrillation (AF). However, its effects on autonomic function and underlying mechanisms remain poorly understood. This study investigated haemodynamic changes following CA explored their potential implications patient outcomes. Methods: Seventy-eight patients with AF underwent were followed up at one, three, six months. Autonomic was assessed using combination of head-up tilt (HUT), handgrip (HG), deep breathing...
Vagal activity is thought to influence atrial electrophysiological properties and play a role in the initiation maintenance of fibrillation (AF). We evaluated effects acute vagal stimulation on conduction, refractoriness pulmonary veins (PVs) inducibility AF. An open-chest epicardial approach was performed New Zealand White rabbits with preserved autonomic innervation. Atrial electrograms were obtained four unipolar electrodes placed epicardially along atria (n = 22) an electrode adapted...
In tetralogy of Fallot (TOF), the dominant ventricular tachycardia substrates are slow-conducting anatomical isthmuses. Surgical correction has evolved, which might have influenced isthmus presence and dimensions.One hundred forty-two postmortem TOF specimens (84/58 corrected/uncorrected) were studied for presence. Isthmus 1 is located between tricuspid annulus right (RV) outflow tract (RVOT) patch/RV incision, 2 RVOT incision pulmonary valve, 3 valve septal defect (patch), 4 (patch)...
Kawasaki disease (KD) is the leading cause of acquired heart in developed countries. Reported incidences vary worldwide but incidence KD has not been established Portugal.The aims study were to describe epidemiologic characteristics and estimate rates among hospitalized children Portugal.This was a descriptive, population-based study, which used hospital discharge records patients <20 years age diagnosed with from Hospital Register database for 2000-2011. Incidence calculated using number...
Kawasaki disease is an acute systemic vasculitis. Cardiac complications are frequent and include endothelial dysfunction in patients with coronary anomalies. So far, the presence of no lesions has not been demonstrated. Peripheral arterial tonometry (Endo-PAT) measures microvascular function response to local ischaemia validated adult population, but its use children scarce. Aim To evaluate as a long-term complication after using Endo-PAT.We evaluated two groups subjects: (1) over 11 years...
The analysis of heart rate variability is nowadays a common method for noninvasive evaluation the autonomic nervous system integrity. In this work we developed an integrated and modular - FisioSinal capable clinical laboratorial behavior using cardiovascular signals in humans animal models. computational tools that were included seek to cover currently most validated methodologies: stochastic analysis, descriptive statistics, auto-regression, fast Fourier transform, discrete Wavelets...
The abnormal neural control of atria has been considered one the mechanisms paroxysmal atrial fibrillation (PAF) pathogenesis. baroreceptor reflex an important role in cardiovascular regulation and may serve as index autonomic function. This study aimed to analyze reflex’s heart rate during upright tilt (HUT) patients with lone PAF. included 68 PAF 34 healthy individuals who underwent baroreflex assessment. Parameters such sensitivity (BRS), number systolic blood pressure (BP) ramps,...
Infantile hemangioma (IH) is one of the most common childhood tumors. There are various medical or surgical therapeutic options, all with suboptimal results. Recently, successful use propranolol for involution IH was described. We report results a single-center experience this option.To prospectively assess efficacy and safety in children infantile hemangioma.We performed prospective analysis clinical data patients referred to pediatric cardiology center baseline cardiovascular assessment...
TANGO2-related metabolic encephalopathy and arrhythmia are a rare, newly recognized, likely under-diagnosed condition. First described in 2016, it is characterized by developmental delay recurrent crisis. During these episodes, patients may present QTc prolongation ventricular arrhythmias.A 13-year-old female, with delay, presented severe rhabdomyolysis an initially normal electrocardiogram (ECG). Due to the worsening of rhabdomyolysis, was identified (QTc 570 ms) oral β-blocker therapy...
Early-onset atrial fibrillation (AF) can be the manifestation of a genetic myopathy. However, specific identification mutation causing fibrosis is rare. We report case young patient with an asymptomatic AF, diagnosed during routine examination. The cardiac MRI revealed extensive and electrophysiology study showed areas low voltage. investigation identified homozygous pathogenic variant in NPPA gene index presence heterozygosity both parents.
Abstract Purpose We examined heart rate variability (HRV) and baroreflex sensitivity (BRS) disease- age-related response at 10-and 60-min after an acute high-intensity interval (HIIE) moderate continuous exercise (MICE) in older adults with without type 2 diabetes mellitus (T2DM) healthy young adults. Methods Twelve male (57–84 years) T2DM (57–76 12 (20–40 completed isocaloric bout of HIIE, MICE, a non-exercise condition randomized order. Time Wavelets-derived frequency domain indices HRV...
Introduction: The Fontan procedure, a palliative surgery for univentricular heart physiology, of-ten reduces exercise capacity and quality of life. This study aimed to evaluate the impact cardiac rehabilitation (CR) on improving outcomes in patients inform evidence-based care. Methods: aged 8-30 participated structured CR program at least three months. included weekly aerobic resistance training sessions, with educational nutritional guidance. Baseline post-CR assessments function, fitness,...
Background: Despite procedural advancements in the management of univentricular heart patients palliated with a Fontan-type circulation, their exercise capacity and quality life remain limited. Postoperative training programs offer potential benefits, yet practical implementation adherence to guidelines are often inadequate. This systematic review meta-analysis aimed evaluate safety, efficacy, optimal modalities for Fontan patients. Method: A search was conducted on August 24, 2023, using...
Background and Objectives: Atrial fibrillation (AF) is increasingly recognised in paediatric patients, presenting unique challenges management due to its association with various underlying heart conditions. This study aimed evaluate the prevalence, strategies, outcomes of AF this population. Materials Methods: A retrospective analysis was conducted at a tertiary cardiology centre, including patients aged ≤18 years diagnosed between January 2015 December 2023. The focused on demographic...