A5013521350- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Central Venous Catheters and Hemodialysis
- Public Health in Brazil
- Renal Diseases and Glomerulopathies
- Clinical Nutrition and Gastroenterology
- Pregnancy and Medication Impact
- Chronic Kidney Disease and Diabetes
- Renal and Vascular Pathologies
- Pediatric Urology and Nephrology Studies
- Adolescent and Pediatric Healthcare
- Platelet Disorders and Treatments
- Metabolism and Genetic Disorders
- Hepatitis C virus research
- Pharmaceutical Practices and Patient Outcomes
- Pharmacological Effects and Toxicity Studies
- Systemic Lupus Erythematosus Research
- Cytomegalovirus and herpesvirus research
- Cell Adhesion Molecules Research
- Child Nutrition and Water Access
- Neurological Complications and Syndromes
- Pharmacovigilance and Adverse Drug Reactions
- Vasculitis and related conditions
Hospital Samaritano de São Paulo
2015-2025
Universidade Federal de São Paulo
2006-2023
Hospital São Paulo
2023
Hospital Garcia de Orta
2022
Universidade Estadual Paulista (Unesp)
1997-2014
Hospital Curry Cabral
1991-2014
Pediatric Nephrology of Alabama
2011
Universidade de São Paulo
2001-2009
Universidade Estadual de Campinas (UNICAMP)
2006
Faculdade de Ciências Médicas da Santa Casa de São Paulo
2006
Abstract. Alport syndrome (AS) is a type IV collagen hereditary disease characterized by the association of progressive hematuric nephritis, hearing loss, and, frequently, ocular changes. Mutations in COL4A5 gene are responsible for more common X-linked dominant form disease. Considerable allelic heterogeneity has been observed. A “European Community Syndrome Concerted Action” established to delineate accurately AS phenotype and determine genotype-phenotype correlations large number...
ABSTRACT. Alport syndrome (AS) is a type IV collagen hereditary disease characterized by progressive hematuric nephritis, hearing loss, and ocular changes. Mutations in the COL4A5 gene are responsible for more common X-linked dominant form of much less severe girls women. A “European Community Syndrome Concerted Action” (ECASCA) group was established to delineate phenotype each gender determine genotype-phenotype correlations large number families. Data concerning 329 families, 250 them with...
Background. The Paulista Registry of Glomerulopathies was created in May 1999 and comprises several centres São Paulo, the most populous Brazilian State, that concentrates people from all regions country who look for health care. Methods. This report includes data 2086 patients Brazil submitted to renal biopsy due presumed diagnosis glomerular diseases, registered prospectively since until January 2005. Data were collected by integrants 11 involved, utilizing a standardized questionnaire....
ABSTRACT Background Congenital anomalies of the kidney and urinary tract (CAKUT) are a common cause failure in childhood. Renal transplantation is modality treatment used for that promotes improved quality life pediatric patients. It believed patients with CAKUT more predisposed to developing graft reflux post‐transplant period, but its influence on survival poorly understood. A comparative analysis between without VUR was made determine impact function Methods retrospective case–control...
Abstract Although the safety of living kidney donation has been well established, prospective studies examining physical and psychosocial aspects donor's quality life are still scarce. Thus, purpose this work was to assess 50 consecutive donors before after transplantation. All were asked respond both a donor questionnaire short‐form 36‐item health survey ( SF ‐36). Interviews individually conducted before, three months after, over one yr Donation considered positive experience by all...
Alport syndrome (AS) is caused by pathogenic mutations in the genes encoding α3, α4 or α5 chains of collagen IV (COL4A3/COL4A4/COL4A5), resulting hematuria, chronic renal failure (CRF), sensorineural hearing loss (SNHL) and ocular abnormalities. Mutations X-linked COL4A5 gene have been identified 85% families (XLAS). In this study, 22 60 probands (37%) unrelated Portuguese families, with clinical diagnosis AS no evidence autosomal inheritance, had detected Sanger sequencing and/or...
The aims of this study were to identify the genetic mutations profile in Brazilian children with nephrotic syndrome (NS) and determine a genotype-phenotype correlation disease.Next-generation sequencing mutation analysis performed on 24 genes related NS cross-sectional involving 95 who underwent kidney transplantation due NS, excluding congenital cases.A total 149 variants identified 22 sequenced genes. classified as pathogenic, likely benign per chance causing disease. NPHS2 was most common...
In this study, the graft outcome in renal allograft recipients with [high cholesterol group (HCG), n = 30] or without [normal (NCG), 42] hypercholesterolemia and triglyceride (HTG), 33] (NTG), 36] hypertriglyceridemia were prospectively compared. At 6 months post-transplantation, no significant difference was observed between groups (NTG compared HTG, NCG HCG) regarding age, presence of arterial hypertension, kind donor (living related cadaveric), immunosuppressive therapy, number rejection...
Reports on the clinical course of mycophenolic acid (MPA)-related colitis in kidney transplant recipients are scarce. This study aimed at assessing MPA-related incidence, risk factors, and progression after transplantation. All patients taking MPA who had colonic biopsies for persistent chronic diarrhea, between 2000 2012, Kidney Transplantation Unit Botucatu Medical School Hospital, Brazil, were included. Cytomegalovirus (CMV) immunohistochemistry was performed all biopsy specimens. Data...
Estimar a prevalência da doença renal crônica terminal (DRCT) pediátrica e avaliar os dados demográficos as características nefrológicas dessa no Estado de São Paulo ano 2008. Estudo observacional, descritivo transversal com base em amostra população indivíduos < 18 anos. A coleta casos ocorreu três formas: 1. Questionário para unidades diálise; 2. Consulta junto à Central Transplantes determinar o número pacientes que estiveram fila transplante renal; 3. ao banco dos registrados...
To estimate the prevalence of pediatric end-stage renal disease and evaluate demographics characteristics in state São Paulo over year 2008.Observational, descriptive, cross-sectional study based on a population sample with subjects < 18 years. The data collecting assumed three forms: 1. A questionnaire for dialysis units; 2. Search Transplant Center to determine number patients who had been transplant waiting list period; 3. database registered at Latin American Collaborative Registry...
End-stage renal disease is a health problem that consumes public and private resources. This study aimed to identify the cost of hemodialysis (either daily or conventional hemodialysis) transplantation in children adolescents.This was retrospective cohort pediatric patients with who underwent followed by kidney transplant. All costs incurred treatment were collected monthly total calculated per patient for each therapy. Subsequently, dynamic panel data model estimated.The included 30 (16...
The performance of a new point-of-care CE-IVD-marked isothermal lab-on-phone COVID-19 assay was assessed in comparison to gold standard real-time reverse transcriptase-PCR method.The study conducted following nonprobability sampling ≥16-year-old volunteers from three different laboratories, using direct mouthwash (N = 24) or nasopharyngeal 191) clinical samples.The demonstrated 95.19% sensitivity and 100% specificity for detection SARS-CoV-2 crude samples 78.95% samples. It also successfully...
Children on long-term parenteral nutrition (PN) are at high risk of iodine deficiency (ID). However, most available information comes from cross-sectional studies. We investigated the status, associated factors, and prevalence hypothyroidism in children with intestinal failure (IF) who were followed up longitudinally.
Trypanosoma cruzi, the causative agent of Chagas’disease assumes two distinct forms in vertebrate hosts: circulating trypomastigote and tissular amastigote. This latter form infects predominantly myocardium, smooth skeletal muscle, central nervous system. The present work describes for first time detection amastigote T. cruzi renal parenchyma a kidney graft recipient one month after transplantation. patient was serologically negative received no blood transfusion prior to transplant. cadaver...
A 49-year-old renal transplant patient, under an 18-year course of immunosuppressive therapy with prednisone and azathioprine and, more recently, plus mycophenolate sodium, developed a cutaneous-subcutaneous infection caused by Histoplasma capsulatum. The clinical presentation consisted slowly enlarging, erythematous infiltrative 25 cm plaque in the major axis on arm. There was no involvement lungs or any other organ. Cure obtained itraconazole treatment after 12 months. Histoplasmosis is...
Abstract The technical aspects of RT in low‐weight children should be specific, particularly with regard to VA . This retrospective study assesses the main options paediatric s and proposes a new strategy for renal artery trajectory when using Ao right iVC sample included 81 patients was categorized into group weighing <16 kg other 16 or more. smaller received graft predominantly on (63%); however, varied more than kg, anastomoses common iliac vessels (46%). In first group, selected...
To identify risk factors for chronic kidney disease progression in Brazilian children and to evaluate the interactions between factors. This was a multicenter prospective cohort São Paulo, involving 209 with CKD stages 3–4. The study outcome included: (a) death, (b) start of replacement therapy, (c) eGFR decrease >50% during followup. Thirteen were tested using univariate regression models, followed by multivariable Cox models. terms interaction variables showing significant association then...