A5053695386- Attention Deficit Hyperactivity Disorder
- Genetic Associations and Epidemiology
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Health, Environment, Cognitive Aging
- Epigenetics and DNA Methylation
- Bipolar Disorder and Treatment
- Medicinal plant effects and applications
- Functional Brain Connectivity Studies
- Toxin Mechanisms and Immunotoxins
- Natural product bioactivities and synthesis
- Diet and metabolism studies
- Nerve injury and regeneration
- Eating Disorders and Behaviors
- Glycosylation and Glycoproteins Research
- Schizophrenia research and treatment
- Urticaria and Related Conditions
- Banana Cultivation and Research
- Phytoplasmas and Hemiptera pathogens
- Birth, Development, and Health
- Microbial Metabolites in Food Biotechnology
- Genetics and Physical Performance
- Synthesis of Tetrazole Derivatives
- Bullying, Victimization, and Aggression
Universitat de Barcelona
2022-2024
Universidad de Granada
2022-2024
Instituto de Investigación Biosanitaria de Granada
2022-2024
Vall d'Hebron Institut de Recerca
2017-2022
Universitat Autònoma de Barcelona
2017-2022
Vall d'Hebron Hospital Universitari
2019-2021
Centro de Investigación Biomédica en Red de Salud Mental
2019
Instituto de Salud Carlos III
2019
Instituto Nacional de las Mujeres
2011
Institut Pasteur
1995-2000
El presente documento analiza un delito que apareció en Costa Rica entre la década de 1970 e inicios 1990. Se llamó “el timo del amor” y consistió estafas eróticas, las víctimas eran hombres fueron engañados antes, durante o después tener encuentro sexual casual. objetivo trabajo es rescatar esta historia para provocar una reflexión sobre características distinguen a los “hombres” “mujeres” aquella época mostrar existía cierta ambigüedad roles género esperados dentro noticias revisadas. La...
Abstract Background: Life expectancy of people with depression is on average 15 years less than that the general population. This excess mortality largely attributed to a deteriorated physical health. Evidence about association between major depressive disorder (MDD) and health still lacking in some areas. The aim this study was explore MDD health-related variables southern Spain. Methods: PISMA-ep cross-sectional based community-dwelling adult Our main outcome current prevalence MDD....
Substance use disorder (SUD) often co-occur at high prevalence with other psychiatric conditions. Among them, attention-deficit and hyperactivity (ADHD) is present in almost one out of every four subjects SUD associated higher severity, more frequent polysubstance dependence increased risk for mental health problems patients. Despite studies suggesting a genetic basis the co-occurrence these two conditions, factors involved joint development both disorders mechanisms mediating causal...
Abstract Background Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental caused by combination of genetic and environmental factors often thought as an entry point into negative life trajectory, including risk for comorbid disorders, poor educational achievement or low income. In the present study, we aimed to clarify causal relationship between ADHD comprehensive range related traits. Methods We used genome-wide association study (GWAS) summary statistics...
Schizophrenia (SZ) is a complex disorder with highly polygenic inheritance. It can be conceived as the extreme expression of continuum traits that are present in general population often broadly referred to schizotypy. However, it still poorly understood how these overlap genetically disorder. We investigated whether risk for SZ associated disorder-related phenotypes (schizotypy, psychotic-like experiences, and subclinical psychopathology) sample 253 non-clinically identified participants....
Abstract Methylphenidate (MPH) is the most frequently used pharmacological treatment in children with attention-deficit/hyperactivity disorder (ADHD). However, a considerable interindividual variability exists clinical outcome. Thus, we performed genome-wide association study of MPH efficacy 173 ADHD paediatric patients. Although no variant reached significance, set genes containing single-nucleotide polymorphisms (SNPs) nominally associated response (P < 0.05) was significantly enriched...
Abstract Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental that often persists into adulthood. There growing evidence epigenetic dysregulation participates in ADHD. Given only limited number of epigenome-wide association studies (EWASs) ADHD have been conducted so far and they mainly focused on pediatric population-based samples, we performed an EWAS clinical sample adults with We report one CpG site four regions differentially methylated between...
Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood-onset neurodevelopmental condition characterized by pervasive impairment of attention, hyperactivity, and/or impulsivity that can persist into adulthood. The aetiology ADHD complex and multifactorial and, despite the wealth evidence for its high heritability, genetic studies have provided modest involvement specific genes failed to identify consistent replicable results. Due lack robust findings, we performed gene-wide...
The Urtica dioica agglutinin (UDA) shares with the superantigens property of activating T cell subsets bearing particular Vβ segments TCR. However, UDA is a lectin capable binding to many glycoproteins on membranes. implication MHC versus other in presentation was presently studied. Using mutant mice lacking class I (MHC-I), II (MHC-II) or both antigens, we provided evidence that MHC-I and MHC-II molecules serve as receptors. Presentation by either one these ensured similar responses...
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental with an estimated heritability of around 70%. Although the largest genome-wide association study (GWAS) meta-analysis on ADHD identified independent loci conferring risk to disorder, molecular mechanisms underlying genetic basis remain be elucidated. To explore biology, we ran two-step transcriptome profiling in peripheral blood mononuclear cells (PBMCs) 143 subjects and 169 healthy controls. Through this exploratory...
Abstract Background Genomewide association studies have found significant genetic correlations among many neuropsychiatric disorders. In contrast, we know much less about the degree to which structural brain alterations are similar disorders and, if so, such similarities a etiology. Methods From Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium, acquired standardized mean differences (SMDs) in regional volume and cortical thickness between cases controls. We had data...