Miyuki Nagahara

ORCID: 0000-0003-2228-5935
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Intraocular Surgery and Lenses
  • Retinal Diseases and Treatments
  • Corneal surgery and disorders
  • Optical Imaging and Spectroscopy Techniques
  • Thermoregulation and physiological responses
  • Radio Frequency Integrated Circuit Design
  • Ocular Surface and Contact Lens
  • Retinal Imaging and Analysis
  • Retinal and Macular Surgery
  • GaN-based semiconductor devices and materials
  • Ophthalmology and Eye Disorders
  • Retinopathy of Prematurity Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Nasolacrimal Duct Obstruction Treatments
  • Silicon Carbide Semiconductor Technologies
  • Cardiovascular Health and Disease Prevention
  • Visual perception and processing mechanisms
  • Ophthalmology and Visual Impairment Studies
  • Sinusitis and nasal conditions
  • Reproductive Biology and Fertility
  • Ocular and Laser Science Research
  • Retinal and Optic Conditions
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Ga2O3 and related materials

Tokushima University
2023-2024

The University of Tokyo
2007-2023

National Center for Global Health and Medicine
2019-2021

Tokai University Hachioji Hospital
2017-2018

University of Tokyo Hospital
1997-2013

Tottori University
2012

Nidek (Japan)
2006

Fujitsu (Japan)
2002-2004

Tokyo Metropolitan Geriatric Hospital
1997-2000

Tokyo Teishin Hospital
1997

To develop a simple, noninvasive method of determining blood velocity and flow through human retinal vessels (RVs), by using the laser speckle validating results bidirectional Doppler velocimetry (LDV).The square blur rate (SBR), quantitative blurring index pattern that parallels moving substances, obtained from flowing glass capillary tubes (RV analogues), correlated with tube diameter, background reflectance absorption, velocity, SBR underlying (choroidal vessel analogues). A nomogram was...

10.1167/iovs.09-4422 article EN Investigative Ophthalmology & Visual Science 2010-08-12

We demonstrate high voltage HFET operation with suppression of gm dispersion and current collapse using an n-type thin GaN cap layer combined SiN passivation a recessed ohmic structure. Polarization-induced surface charge was controlled. Off state on-state breakdown voltages were 140 V 70 V. obtained power HFETs CW 35 without any heat sinking method.

10.1109/iedm.2001.979574 article EN 2002-11-13

Reactions of 3-carboxymethylrhodanine (1) with aldehydes (2a-u) afforded stereoselectively the 5-mono-alkylmethylidene-3-carboxymethylrhodanines (3a-u). The configuration 5-monoalkylmethylidene-3-carboxymethylrhodanine (3k) were examined by X-ray structure analysis and confirmed to be Z-configuration. stereoselective reaction path was discussed. Several 5-dialkylmethylidene-3-carboxymethylrhodanines (15a-f) alkylamino derivatives 3-carboxymethylrhodanines (18a-o) also prepared. These...

10.1248/cpb.38.1911 article EN Chemical and Pharmaceutical Bulletin 1990-01-01

10.1007/s00417-013-2288-5 article EN Graefe s Archive for Clinical and Experimental Ophthalmology 2013-02-26

To evaluate tear meniscus (TM) changes in external dacryocystorhinostomy (ex-DCR) with quantitative measurement of height (TMH), area (TMA), and volume (TMV) using anterior segment optical coherence tomography (AS-OCT).Twenty-five eyes from 21 patients (11 males 10 females) primary acquired nasolacrimal duct obstruction (PANDO) who received ex-DCR May 2010 to April 2011 were evaluated prospectively on their TMH, TMA, TMV by AS-OCT. Measurements performed before surgery (Pre) 2 weeks (2W),...

10.1167/iovs.13-12692 article EN Investigative Ophthalmology & Visual Science 2014-01-29

<h3>AIMS</h3> To study the effects of segmental scleral buckling and encircling procedures on tissue circulation in human optic nerve head (ONH) choroid retina. <h3>METHODS</h3> Using laser speckle method, normalised blur (NB) value, a quantitative index blood velocity, was measured every 0.125 seconds averaged over three pulses (NB<sub>ONH</sub>) retina (NB<sub>ch-ret</sub>) 10 patients with unilateral rhegmatogenous retinal detachment (mean age 52 (SD 17)). NB<sub>ONH</sub>,...

10.1136/bjo.84.1.31 article EN British Journal of Ophthalmology 2000-01-01

<b>Aim:</b> To investigate the effect of myopia and myopic choroidal neovascularisation (CNV) on retrobulbar circulation in central retinal artery (CRA) vein (CRV) posterior ciliary (PCA). <b>Methods:</b> 52 subjects with without were included study. Retrobulbar was measured using colour Doppler imaging. Analysis correlation degree blood flow velocity parameters done. Circulatory differences between eyes patients unilateral neovascular degenerative estimated. <b>Results:</b> The analysis...

10.1136/bjo.86.7.771 article EN British Journal of Ophthalmology 2002-07-01

The purpose of the present study was to effect a single instillation latanoprost on human optic nerve head (ONH) and retinal circulation. Using laser-speckle tissue blood flow analysis, normalized blur (NB; quantitative index velocity) measured every 0.125 sec at temporal ONH site free visible surface vessels. Measurements were averaged for 3 cardiac cycles (NB(ONH)). Color Doppler Imaging (CDI) also used evaluate peak systolic velocity (PSV), endo-diastolic (EDV), resistive (RI) in central...

10.1089/108076801753266785 article EN Journal of Ocular Pharmacology and Therapeutics 2001-10-01

We report 4 cases of complete posterior dislocation an intraocular lens (IOL) in the capsular bag occurring a mean 5.5 years after uneventful cataract surgery. In all cases, chamber IOLs were fixated within capsulorhexis. The patients experienced sudden loss vision without episode trauma or ocular disease. Using 3-port pars plana vitrectomy, explanted through limbal incision and new IOL was sutured to ciliary sulcus. Histological examination indicated that zonular fibers severed at site...

10.1016/s0886-3350(01)01178-6 article EN Journal of Cataract & Refractive Surgery 2002-09-01

AbstractPURPOSE. To study the effect of topical 0.5% timolol and 2% carteolol on tissue blood flow in human optic nerve head (ONH). METHODS. Using a laser speckle analyzer, normalized blur (NB), quantitative index velocity, was measured every 0.125 s temporal site ONH free visible surface vessels averaged over 3 cardiac pulses (NB ONH) . serve as baseline, NB intraocular pressure (IOP) both eyes, (BP) pulse rate (PR) were recorded healthy volunteers before, 1.5, 4.5 hrs after 30L...

10.1076/ceyr.16.11.1102.5101 article EN Current Eye Research 1997-01-01

Purpose . To investigate clinical results on bleb-related endophthalmitis (BRE) after trabeculectomy treated with pars plana vitrectomy (PPV) and to evaluate influence factors for visual prognosis. Methods Investigating medical records retrospectively, BRE was defined as an induced by bleb infection. A total of 2018 eyes 1225 patients who had between December 2000 July 2013 were included in this study. Eleven 11 performed PPV. Results The mean age 56.6 years. period onset 7.4 from starting...

10.1155/2015/923857 article EN cc-by Journal of Ophthalmology 2015-01-01

There have been no reports to date on long-term betaxolol instillation effects the human optic nerve head (ONH) tissue circulation. The purpose of this study was effect topical 0.5% blood velocity in ONH. Using a laser-speckle flow analyzer, normalized blur (NB; quantitative index velocity) measured every 0.125 seconds at temporal ONH site free visible surface vessels. Measurements were averaged for 3 cardiac cycles (NBONH). For baseline comparison (day 0), recordings bilateral NBONH and...

10.1089/jop.1999.15.313 article EN Journal of Ocular Pharmacology and Therapeutics 1999-08-01

To investigate the effects of lomerizine, a Ca2+ antagonist, on ocular tissue circulation in rabbits and optic nerve head (ONH) choroid healthy volunteers.Lomerizine (0.1 [n=10] or 0.3 [n=11] mg/kg) vehicle solution (n=11) was injected intravenously urethane-anesthetized rabbits, blood flow retina, choroid, iris-ciliary body measured by microsphere method that ONH H2 gas-clearance [n=6] [n=9] mg/kg vehicle, n=6). Oral 5 mg lomerizine placebo administered to volunteers (n=8) crossover study,...

10.1167/iovs.02-1173 article EN Investigative Ophthalmology & Visual Science 2003-10-24
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