A5048831191- Ion channel regulation and function
- Analytical Chemistry and Chromatography
- Synthesis and biological activity
- Heavy Metal Exposure and Toxicity
- Analytical Methods in Pharmaceuticals
- Essential Oils and Antimicrobial Activity
- Asymmetric Synthesis and Catalysis
- Computational Drug Discovery Methods
- Cholinesterase and Neurodegenerative Diseases
- Cancer Treatment and Pharmacology
- Cancer therapeutics and mechanisms
- Chemical Synthesis and Analysis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Neuroscience and Neuropharmacology Research
- Trace Elements in Health
- Innovative Microfluidic and Catalytic Techniques Innovation
- Molecular spectroscopy and chirality
- Nicotinic Acetylcholine Receptors Study
- Mercury impact and mitigation studies
- Multiple Myeloma Research and Treatments
- Cardiac electrophysiology and arrhythmias
- Electrochemical Analysis and Applications
- Chemical synthesis and alkaloids
- Inorganic and Organometallic Chemistry
- Circadian rhythm and melatonin
University of Bari Aldo Moro
2016-2025
Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase
2024
Chromium (Cr) is a common element in the Earth’s crust. It may exist different oxidation states, Cr(0), Cr(III) and Cr(VI), with Cr(VI) being relatively stable largely predominant. Chromium’s peculiarity that its behavior relies on valence state. trace humans plays major role glucose fat metabolism. The beneficial effects of obesity types 2 diabetes are known. has been long considered an essential element, but now it reclassified as nutritional supplement. On other hand, human carcinogen...
Curcumin, a hydrophobic polyphenol extracted from the rhizome of Curcuma longa, is now considered candidate drug for treatment neurological diseases, including Parkinson’s Disease (PD), Alzheimer’s (AD), Huntington’s (HD), Multiple Sclerosis (MS), Amyotrophic Lateral (ALS), and prion disease, due to its potent anti-inflammatory, antioxidant potential, anticancerous, immunomodulatory, neuroprotective, antiproliferative, antibacterial activities. Traditionally, curcumin has been used medicinal...
Sweet cherry (Prunus avium L.) is one of the most popular and appreciated temperate fruit not only for its sensory nutritional properties, but also content in bioactive compounds. Consumption sweet cherries brings beneficial effects on to health, which include prevention modulatory several chronic diseases such as (diabetes mellitus, cancer, cardiovascular other inflammatory diseases). The presence natural polyphenolic compounds with high antioxidant potential might drive partly explain...
Thallium (Tl) is released into the environment, where present at very low levels, from both natural and anthropogenic sources. Tl considered as one of most toxic heavy metals; it a non-essential metal, in concentrations humans. toxicity causes dermatological gastrointestinal diseases disorders nervous system, may even result death. Many isotopes exist, with different uses. One this metal (201Tl) used cardiovascular scintigraphy for diagnosis malignant tumors such breast or lung cancer...
Mentha piperita L. essential oil (EO) is employed for external use as antipruritic, astringent, rubefacient and antiseptic. Several studies demonstrated its significant antiviral, antifungal antibacterial properties. The aim of this work the study synergistic effects M. EO with antibacterials antifungals that are widely available currently prescribed in therapies against infections. observed strong synergy may constitute a potential new approach to counter increasing phenomenon multidrug...
In recent years, the increase of bacteria antibiotic- resistance has been a severe problem for public health. A useful solution could be to join some phytochemicals naturally present in essential oils (EOs) existing antibiotics, with aim their efficacy therapies. According vitro studies, EOs and components show such effects. Among them, we studied activity Cinnammonum zeylanicum, Mentha piperita, Origanum vulgare, Thymus vulgaris on bacterial biofilm synergism when used association common...
Pomegranate peels are the major by-products of processing pomegranate juice. Scientific research studies have shown that an extraordinary source bioactive compounds, most which can be converted into value added products. From this point view, present study was carried out with aim providing a solid basis for use whole (Akko variety) as nutraceutical such β-glucans. Moreover, acetone (S1) and methanolic (S2) extracts, obtained in preliminary stage β-glucan isolation procedure, been tested...
Pomegranate is an old plant made up by flowers, roots, fruits and leaves, native to Central Asia principally cultivated in the Mediterranean California (although now widespread almost all over globe). The current use of this precious regards not only exteriority fruit (employed also for ornamental purpose) but especially nutritional and, still potential, health benefits that come out from various parts composing one (carpellary membranes, arils, seeds bark). Indeed, phytochemical composition...
Ellagic acid (EA), a polyphenolic constituent of plant origin, has been thoroughly investigated for its hypothesised pharmacological properties among which antioxidant and neuroprotective activities are included. The present study was designed to explore whether EA could attenuate heavy metal (cadmium, mercury, lead)-induced neurotoxicity in SH-SY5Y cells, were utilized as model system brain cells. MTT LDH assays performed examine the viability cells after exposure Cd, Hg, Pb (either...
This study explores how a simple argentometric titration-like approach could be evolved into versatile, scalable, fast, and robust strategy for the production of AgCl/quaternary ammonium compounds (QACs) colloidal nanoantimicrobials (NAMs). These systems, which are green, stable, cost-effective, reproducible found to effective against wide range food pathogenic bacteria biofilms. The option large-scale such suspensions was explored via use peristaltic pump. various types biosafe QACs...