Andy Zhang

ORCID: 0000-0003-2306-0340
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About
Contact & Profiles
Research Areas
  • Mechatronics Education and Applications
  • Engineering Education and Pedagogy
  • Electronic Packaging and Soldering Technologies
  • Engineering Education and Curriculum Development
  • Advanced Fluorescence Microscopy Techniques
  • Experimental Learning in Engineering
  • Silicon Carbide Semiconductor Technologies
  • Cell Image Analysis Techniques
  • Data Analysis with R
  • Hydrological Forecasting Using AI
  • 3D IC and TSV technologies
  • Advanced Neural Network Applications
  • Photoacoustic and Ultrasonic Imaging
  • Spectroscopy and Laser Applications
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Plasma Diagnostics and Applications
  • Integrated Circuits and Semiconductor Failure Analysis
  • Design Education and Practice
  • Advanced Sensor Technologies Research
  • Vibration and Dynamic Analysis
  • Ion channel regulation and function
  • Material Properties and Processing
  • Robotics and Automated Systems
  • Combustion and flame dynamics
  • Systems Engineering Methodologies and Applications

Nankai University
2022-2025

Yangtze University
2024-2025

Union Hospital
2024

Huazhong University of Science and Technology
2024

New York City College of Technology
2012-2024

City College of New York
2020-2024

City College
2015-2024

Chemnitz University of Technology
2024

Engineering (Italy)
2024

The Ohio State University
2024

Marine ships are the transport vehicle in ocean and instance segmentation of marine is an accurate efficient analysis approach to achieve a quantitative understanding ships, for example, their relative locations other or obstacles. This spatial information crucial developing unmanned avoid crashing. Visible light imaging, e.g. using our smartphones, way obtain images however, so far there lack suitable open-source visible datasets which could potentially slow down development ships. To...

10.1371/journal.pone.0279248 article EN cc-by PLoS ONE 2023-02-24

A novel α7 nAChR agonist, 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (24, CP-810,123), has been identified as a potential treatment for cognitive deficits associated with psychiatric or neurological conditions including schizophrenia and Alzheimer's disease. Compound 24 is potent selective compound excellent pharmaceutical properties. In rodent, the displays high oral bioavailability brain penetration affording levels of receptor occupancy in vivo efficacy auditory...

10.1021/jm9015075 article EN Journal of Medicinal Chemistry 2009-12-31

In the remote sensing field, synthetic aperture radar (SAR) is a type of active microwave imaging sensor working in all-weather and all-day conditions, providing high-resolution SAR images objects such as marine ships. Detection instance segmentation ships has become an important question sensing, but current deep learning models cannot accurately quantify because multi-scale property images. this paper, we propose feature pyramid network (MS-FPN) to achieve simultaneous detection The...

10.3390/rs14246312 article EN cc-by Remote Sensing 2022-12-13

Introduction Branches are important for soybean yield, and previous studies examining branch traits have primarily focused on number (BN), while research assessing internode (BIN), length (BL), (BIL) remains insufficient. Methods A recombinant inbred line (RIL) population consisting of 364 lines was constructed by crossing ZD41 ZYD02878. Based the RIL population, we genetically analyzed four using different GWAS methods including efficient mixed-model association expedited, restricted...

10.3389/fgene.2025.1484146 article EN cc-by Frontiers in Genetics 2025-03-03

Myelin pathology is known to play a central role in disorders such as multiple sclerosis (MS) among others. Despite this, the pathological mechanisms underlying these conditions are often difficult unravel. Conventional techniques like immunohistochemistry or dye-based approaches, do not provide temporal characterization of pathophysiological aberrations responsible for myelin changes human specimens. Here, circumvent this curb, we present label-free, live-cell imaging approach using recent...

10.1371/journal.pone.0310663 article EN cc-by PLoS ONE 2025-03-31

Ca(2+) release from the sarcoplasmic reticulum via ryanodine receptor (RyR2) activates cardiac myocyte contraction. An important regulator of RyR2 function is FKBP12.6, which stabilizes in closed state during diastole. Beta-adrenergic stimulation has been suggested to dissociate FKBP12.6 RyR2, leading diastolic leakage and ventricular tachycardia (VT). We tested hypothesis that overexpression myocytes can reduce susceptibility VT stress conditions. developed a mouse model with conditional...

10.1161/circulationaha.107.731893 article EN Circulation 2008-04-01

Distinguishing tumors from normal brain cells is important but challenging in glioma surgery due to the lack of clear interfaces between two. The ability label-free third harmonic generation (THG) microscopy combination with automated image analysis quantitatively detect infiltration fresh, unprocessed tissue real time assessed. THG images reveal increased cellularity grades II-IV samples 23 patients, as confirmed by subsequent hematoxylin and eosin histology. An quantification workflow...

10.1002/advs.201900163 article EN cc-by Advanced Science 2019-04-05

Abstract This research to practice full paper presents an innovative of 'Engineering Education' in respect Robotics Mechanical Engineering Technology. The remote robotics classes are currently implemented wildly all over the world due pandemic. ones that require intensive hands-on practices, especially at colleges which provide mechanical engineering technology (MET) degrees. MET programs mainly focus on skills instead theoretical analysis. One educational goals is cultivate future...

10.18260/1-2--37408 article EN mit 2020 ASEE Virtual Annual Conference Content Access Proceedings 2024-02-20

Abstract Third harmonic generation (THG) microscopy is a label‐free imaging technique that shows great potential for rapid pathology of brain tissue during tumor surgery. However, the interpretation THG images should be quantitatively linked to more standard techniques, which so far has been done qualitatively only. We establish here such quantitative link between mouse and all‐nuclei‐highlighted fluorescence images, acquired simultaneously from same area. For comparison substantial pair we...

10.1002/jbio.201600256 article EN Journal of Biophotonics 2017-05-02

Significance Primary cilia are important organelles that exist in almost all eukaryotic cells. Intraflagellar transport (IFT) is a motor-protein–driven bidirectional intracellular mechanism cilia. Previous studies have shown motors Caenorhabditis elegans chemosensory undergo rapid turnarounds to effectively work together driving orderly IFT. The of motor has, however, remained unclear. Here, using combination advanced fluorescence imaging and single-molecule analysis, we directly show the...

10.1073/pnas.2115089118 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2021-11-03

Abstract The fatigue life prediction of the electronic packages under dynamic loading conditions is an increasingly important area research, with direct application in packaging industries. Current methodologies are, general, developed through a finite element (FE) model that correlated using experimental data measured sweep sine testing. frequency response function (FRF) generated by testing may suffer from leakage and windowing signal not work correctly, which results shift amplitude...

10.1115/1.4056886 article EN Journal of Electronic Packaging 2023-02-09

Introduction Soybean stem diameter (SD) and branch (BD) are closely related traits, genetic clarification of SD BD is crucial for soybean breeding. Methods were genetically analyzed by a population 363 RIL derived from the cross between Zhongdou41 (ZD41) ZYD02878 using restricted two-stage multi-locus genome-wide association, inclusive composite interval mapping, three-variance component random SNP effect mixed linear modeling. Then candidate genes major QTLs selected selection model...

10.3389/fpls.2024.1388365 article EN cc-by Frontiers in Plant Science 2024-05-31

Distance/online learning is becoming a necessary form at academic institutions, and the growth in distance/online has been outpacing enrollment growth.The pandemic even further pushing to peak based on census from United States Census Bureau.According data of EducationData.org, 98% institutions have moved most in-person classes online sections.The robotics are also currently provided across country.Because class kind intensive hands-on class, course prevents students implementing various...

10.18260/1-2--41355 article EN 2024-02-06

Abstract Motivation The morphologies contained in 3D third harmonic generation (THG) images of human brain tissue can report on the pathological state tissue. However, complexity THG makes usage modern image processing tools, especially those filtering, segmentation and validation, to extract this information challenging. Results We developed a salient edge-enhancing model anisotropic diffusion for based higher order statistics. split intrinsic 3-phase problem into two 2-phase problems, each...

10.1093/bioinformatics/btx035 article EN Bioinformatics 2017-01-27

Gβγ subunits mediate many different signaling processes in various compartments of the cell, including nucleus. To gain insight into functions nuclear signaling, we investigated functional role regulation GPCR-mediated gene expression primary rat neonatal cardiac fibroblasts. We identified a novel, negative, regulatory for Gβ1γ dimer fibrotic response. Depletion Gβ1 led to derepression response at mRNA and protein levels under basal conditions an enhanced after sustained stimulation...

10.1016/j.jbc.2023.103064 article EN cc-by Journal of Biological Chemistry 2023-02-24

This paper describes two types of test vehicles including PCB with 77x77mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 140x140mm . The first TV is taken from drop spec (JESD22-B111A) so that the same can be shared. Various vibration tests acceleration strain calibration have been performed in five (5) different labs (Coded as L1-5) on TVs. include sine sweep at 1-4G random 3.1 to 10Grms. results show correlation natural...

10.1109/ectc51909.2023.00056 article EN 2023-05-01

The advance of mobile electronics applications has been demanding higher drop/shock reliability performance under more severe impacts. This in turn is requiring the board level (BLR) drop test to be able reach peak acceleration, particularly than 5000 G. One method this high acceleration use an apparatus called Dual Mass Shock Amplifier (DMSA) attached onto a conventional tester. tester typically generates primary impact range 1000 ~ 2000 G, and DMSA, which hangs above table continues fall...

10.1109/ectc.2014.6897483 article EN 2014-05-01

Third harmonic generation (THG) microscopy shows great potential for instant pathology of brain tissue during surgery. However, the rich morphologies contained and noise associated makes image restoration, necessary quantification THG images, challenging. Anisotropic diffusion filtering (ADF) has been recently applied to restore images normal brain, but ADF is hard-to-code, time-consuming only reconstructs salient edges. This work overcomes these drawbacks by expressing as a tensor...

10.1002/jbio.201800129 article EN cc-by Journal of Biophotonics 2018-06-30

The existing configuration of the JESD22-B111 test board does not impose identical strains during drop on all 15-components board, requiring a large numbers boards to develop meaningful life distributions. Two new candidate designs intended serve as replacements for JEDEC have been analyzed. Configuration-A includes four components located symmetrically square 3-inch × printed circuit board. Configuration-B one-component In this paper, explicit finite element models along with high speed...

10.1109/ectc.2014.6897272 article EN 2014-05-01

According to an analysis conducted by Greenpeace, "one in three Americans is at risk of a poison gas disaster living near one hundreds chemical facilities that store and use highly toxic chemicals. A just these could kill or injure thousands people with acute poisoning [1]." Because the common proximity between residences United States (U.S.), hazardous detection early warning systems vital frequently missing feature public safety systems. In many instances, cost equipment monitoring...

10.1109/ghtc.2012.19 article EN 2012-10-01

To design the pulse information which includes parameter of pulse-position, pulse-number, pulse-shape and pulse-force acquisition analysis system with function dynamic recognition, research digitalization visualization some common cardiovascular mechanism single pulse.To use flexible sensors to catch radial artery pressure wave utilize high frequency B mode ultrasound scanning technology synchronously obtain extension axial movement, by way images, then gathered was analyzed processed...

10.4314/ahs.v14i3.34 article EN cc-by African Health Sciences 2014-09-05

Narrow bandgap semiconductors GaSb, InAs, and InSb are important building blocks for infrared photodetectors based on type-II quantum dots or an InAs/GaSb strained layer superlattice. Understanding the surface chemical composition of these materials can provide valuable information that enables optimization device passivation techniques leading towards leakage free IR photodetectors. We report investigation into Ga-, In-, Sb-, As-oxides other species untreated, dry etched thermally treated...

10.1117/12.919334 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2012-05-01
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