A5063493356- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Surgical Treatments
- Advances in Oncology and Radiotherapy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Hepatitis C virus research
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Hepatitis B Virus Studies
- Clinical practice guidelines implementation
- Innovations in Medical Education
- Cancer Treatment and Pharmacology
- Pancreatic and Hepatic Oncology Research
- Bladder and Urothelial Cancer Treatments
- Antioxidant Activity and Oxidative Stress
- Cancer Immunotherapy and Biomarkers
- Phytoestrogen effects and research
- Cancer Risks and Factors
- Morinda citrifolia extract uses
- Ginseng Biological Effects and Applications
- Patient Safety and Medication Errors
- Pharmaceutical Practices and Patient Outcomes
- Economic and Financial Impacts of Cancer
The University of Texas MD Anderson Cancer Center
2013-2024
The University of Texas Health Science Center at Houston
2017
Harris Health System
2016
The University of Kansas Cancer Center
2016
Sarcomatoid renal cell carcinoma often has an aggressive clinical course characterized by rapid disease progression. We evaluate prognostic factors for patient survival and the effect of treatment on outcome.Between 1987 1998, 108 patients were classified as having sarcomatoid at our institution. reviewed records these to identify pathological variables. The Kaplan-Meier method was used determine differences in overall survival.A total 96 (89%) symptomatic presentation. localized kidney 25...
Patients with type II diabetes mellitus (DM) have an increased risk of adenomatous colorectal (CRC) polyps and CRC cancer. The use the anti-hyperglycemic agent metformin is associated a reduced incidence cancer-related deaths.
<h3>Importance</h3> Universal screening of patients with newly diagnosed cancer for hepatitis B virus (HBV), C (HCV), and HIV is not routine in oncology practice, experts disagree about whether universal should be performed. <h3>Objective</h3> To estimate the prevalence HBV, HCV, infection among persons cancer. <h3>Design, Setting, Participants</h3> Multicenter prospective cohort study (ie, identified within 120 days diagnosis) at 9 academic community institutions affiliated SWOG (formerly...
A man in his 70s with metastatic colorectal cancer presented worsening clinical symptoms and imaging studies concerning for disease progression. He had received two cycles of pembrolizumab, but due to symptomatic presentation significant decline performance status, there was concern disease. Transitioning hospice briefly considered, given the notable increase tumour size. Despite presence radiographic findings, pseudoprogression—defined as an size(s) and/or visual appearance new lesion(s),...
Long wait times at chemotherapy infusion centers adversely affect patients' perception of quality care and result in patient dissatisfaction. We conducted a improvement initiative busy community hospital to improve center efficiency reduce time, while maintaining safety avoiding waste.We used coordinated collaborative effort between providers, nurses, pharmacists ensure completion orders, review laboratory data, prepreparation 1 day ahead each patient's scheduled appointment. Monthly...
500 Background: Pts frequently treated with OC in the adjuvant, perioperative, or first-line setting for CRC may be retreated oxaliplatin at time of relapse progression; efficacy retreatment is not known. Methods: Under an IRB-approved protocol, pharmacy records identified 1,166 pts who received our institution from 1/1/2004-12/30/2009. were categorized as having previously initially indication adjuvant (group A, n=29), unresectable metastatic disease B, n=75), perioperative therapy...
Curative-intent therapy for stage II/III rectal cancer is necessarily complex. Current guidelines by the National Comprehensive Cancer Network recommend preoperative concurrent chemoradiation followed resection and additional adjuvant chemotherapy. We used standard quality improvement methodology to implement a cost-effective intervention that reduced time from diagnosis treatment of patients with approximately 30% in large public hospital Houston, Texas. Implementation program resulted...
SWOG initiated a cancer care delivery research study of virus infection rates among newly diagnosed patients. This will inform viral screening guidelines in oncology clinics.In first step 'vanguard' phase, we evaluated the feasibility multiple procedures. Site investigators were surveyed to obtain feedback on implementation.Much higher enrollment occurred at sites where all physicians participated and testing was performed as routine practice. These procedures be required going forward....
Patients with rectal cancers, due to the unique location of tumor, have a recurrence pattern distinct from colon cancers. Advances in adjuvant therapy over last three decades played an important role improving patient outcomes. This article serves review clinical studies that lay basis for our current standard-of-care treatment patients locally advanced cancer, as well touch upon future ongoing experimental trials chemoradiation therapy.
e14648 Background: Osteoclastic giant cell tumor of the pancreas (OGCTP) is a rare subtype pancreatic cancer. It has been variably described in case reports as cancer with pleomorphic, anaplastic, spindle cell, undifferentiated or mixed histology. Clinical and pathologic data regarding this are very limited. Methods: We conducted retrospective review patient records above histologies at single institution from 1994 to 2008. Archival pathology specimens were independently reviewed by two...
Education is an important component of cancer care; however, most clinician educators (CEs) receive little formal training in this area. Little known about the factors that influence oncologists to pursue a career as CE. The primary objective study was determine current state oncologists' perceptions regarding educator role.A one-time cross-sectional survey administered program directors/associate directors (PDs/APDs) and fellows November 2021. meant elicit their CE role, opportunities,...
141 Background: The treatment of stage II/III rectal cancer is complex and requires multidisciplinary collaboration. Delays in definitive may increase morbidity compromise outcomes. goal was to reduce the time from pathologic diagnosis initiation by 30% for patients with at Lyndon B. Johnson General Hospital (LBJGH), which provides care uninsured underinsured Harris County, TX. Methods: charts 32 diagnosed between July 2012 December 2013 were reviewed. Baseline data regarding diagnostic...
e14626 Background: Unresectable hilar cholangiocarcinoma is commonly treated with gemcitabine-based chemotherapy. Consolidative radiotherapy (RT) increasingly being used for patients localized disease. Biliary obstruction and cholangitis are important causes of morbidity mortality in UHC. The impact MMT vs. chemotherapy alone on survival biliary has not yet been characterized. Methods: Using the MD Anderson tumor registry, we identified 137 UHC from 1998-2009 retrospectively reviewed their...
e22176 Background: Colorectal cancer (CRC) may experience substantial symptom burden that is often exacerbated by standard chemotherapy. It’s a high price to pay for cure and persists into survivorship. Minocycline readily available, low-cost antibiotic with anti-inflammatory properties. This ACS-funded proof-of-concept study investigated minocycline’s ability reduce symptoms during chemotherapy in phase II randomized, double-blinded, placebo-controlled clinical trial. Methods: Patients CRC...