A5021434725- Cosmology and Gravitation Theories
- Traumatic Brain Injury Research
- Space Science and Extraterrestrial Life
- Traumatic Brain Injury and Neurovascular Disturbances
- History and Developments in Astronomy
- Sports injuries and prevention
- Injury Epidemiology and Prevention
- Scientific Research and Discoveries
- Immunotherapy and Immune Responses
- International Science and Diplomacy
- Galaxies: Formation, Evolution, Phenomena
- Dark Matter and Cosmic Phenomena
- Astronomy and Astrophysical Research
- Cerebrospinal fluid and hydrocephalus
- Immune Cell Function and Interaction
- Botulinum Toxin and Related Neurological Disorders
- Cardiac Arrest and Resuscitation
- T-cell and B-cell Immunology
- Relativity and Gravitational Theory
- Glycosylation and Glycoproteins Research
- Shoulder Injury and Treatment
- Stellar, planetary, and galactic studies
- Cerebral Palsy and Movement Disorders
- Computational Physics and Python Applications
- Gamma-ray bursts and supernovae
Imperial College London
2024
Traffic Injury Research Foundation
2022-2024
University of North Carolina Wilmington
2024
University College London
2019-2024
University of Birmingham
2024
University of Chicago
2011-2023
University of California, San Diego
2020-2023
Australian National University
2005-2023
University of California, Los Angeles
2023
English Institute of Sport
2020-2022
The 2017 Concussion in Sport Group (CISG) consensus statement is designed to build on the principles outlined previous statements1–4 and develop further conceptual understanding of sport-related concussion (SRC) using an expert consensus-based approach. This document developed for physicians healthcare providers who are involved athlete care, whether at a recreational, elite or professional level. While agreement exists principal messages conveyed by this document, authors acknowledge that...
The new 2012 Zurich Consensus statement is designed to build on the principles outlined in previous documents and develop further conceptual understanding of this problem using a formal consensus-based approach. A detailed description consensus process at end document under Background section. This developed primarily for use by physicians healthcare professionals who are involved care injured athletes, whether recreational, elite or professional level.
This paper is a revision and update of the recommendations developed following 1st
The inflationary prediction of a flat Universe is at odds with current determinations the matter density $({\ensuremath{\Omega}}_{M}\ensuremath{\simeq}0.2\ensuremath{-}0.4).$ This dilemma can be resolved if smooth component contributes remaining energy $({\ensuremath{\Omega}}_{X}=1\ensuremath{-}{\ensuremath{\Omega}}_{M}).$ We parametrize by its equation state, ${p}_{X}=w{\ensuremath{\rho}}_{X},$ and show that $X$CDM $w\ensuremath{\simeq}\ensuremath{-}0.6,$...
For over two decades, the Concussion in Sport Group has held meetings and developed five international statements on concussion sport. This 6th statement summarises processes outcomes of International Conference Amsterdam 27-30 October 2022 should be read conjunction with (1) methodology paper that outlines consensus process detail (2) 10 systematic reviews informed conference outcomes. Over 3½ years, author groups conducted predetermined priority topics relevant to The format conference,...
Mild traumatic brain injury (mTBI), or concussion, in children is a rapidly growing public health concern because epidemiologic data indicate marked increase the number of emergency department visits for mTBI over past decade. However, no evidence-based clinical guidelines have been developed to date diagnosing and managing pediatric United States.To provide guideline based on previous systematic review literature obtain assess evidence toward developing recommendations care professionals...
The presence of dark energy in the Universe is inferred directly from accelerated expansion Universe, and, indirectly, measurements cosmic microwave background (CMB) anisotropy. Dark contributes about two-thirds critical density, smoothly distributed, has large negative pressure, and very mysterious. For now, all its discernible cosmological consequences follow effect on rate Universe. Absent a compelling theoretical model (or even class models), we describe by equation state...
This paper is a revision and update of the recommendations developed following 1st (Vienna 2001), 2nd (Prague 2004), 3rd (Zurich 2008) International Consensus Conference on Concussion in Sport based deliberations at 4th held Zurich, November 2012.1–3The new 2012 Zurich statement designed to build principles outlined previous documents develop further conceptual understanding this problem using formal consensus-based approach. A detailed description consensus process end document under...
Obesity-associated increases in adipose tissue (AT) CD11c(+) cells suggest that dendritic (DC), which are involved the recruitment and activation of macrophages, may play a role determining AT liver immunophenotype obesity. This study addressed this hypothesis. With use flow cytometry, electron microscopy, loss-and-gain function approaches, contribution DC to pattern immune cell alterations obesity was assessed. In there substantial, high-fat diet (HFD)-induced increase DC. AT, these were...
Abstract The definitions of tolerogenic vs immunogenic dendritic cells (DC) remain controversial. Immature DC have been shown to induce T regulatory (Treg) specific for foreign and allogeneic Ags. However, we previously reported that mature (mDC) prevented the onset autoimmune diabetes, whereas immature (iDC) were therapeutically ineffective. In this study, islet-specific CD4+ from BDC2.5 TCR-transgenic mice stimulated in absence exogenous cytokine with iDC or mDC pulsed high- low-affinity...
Abstract Noninvasive methods to image the trafficking of phenotypically defined immune cells are paramount as we attempt understand adaptive immunity. A 19 F MRI‐based methodology for tracking and quantifying a phenotype is presented. These were applied murine inflammation model using antigen‐specific T cells. The that intracellularly labeled ex vivo with perfluoropolyether (PFPE) nanoemulsion transferred host receiving localized inoculation antigen. Longitudinal MRI over 21 days revealed...
The duration of T cell receptor contact with antigen modulates the pattern downstream signaling to determine CD4 + fate.
Through a partnership with the National Institute of Neurological Disorders and Stroke (NINDS), Institutes Health, Department Defense, development Sport-Related Concussion (SRC) Common Data Elements (CDEs) was initiated. The aim this collaboration to increase efficiency effectiveness clinical research studies treatment outcomes, data quality, facilitate sharing across studies, reduce study start-up time, more effectively aggregate information into metadata results, educate new investigators....
In March 2004, a multidisciplinary conference, "ITB Therapy Best Practice Forum," was held in Minneapolis, Minnesota. The goal of the conference to develop recommendations for techniques implant intrathecal baclofen (ITB) pump and catheter systems more effectively with fewer complications. authors present optimal implantation, including subfascial placement; insertion Tuohy needle an oblique, paramedian trajectory; positioning tip at levels commensurate therapeutic indication: approximately...