Obesity-associated increases in adipose tissue (AT) CD11c(+) cells suggest that dendritic (DC), which are involved the recruitment and activation of macrophages, may play a role determining AT liver immunophenotype obesity. This study addressed this hypothesis. With use flow cytometry, electron microscopy, loss-and-gain function approaches, contribution DC to pattern immune cell alterations obesity was assessed. In there substantial, high-fat diet (HFD)-induced increase DC. AT, these were...

The contribution of natural killer T (NKT) cells to the pathogenesis metabolic abnormalities obesity is controversial. While combined genetic deletion NKT and CD8+ T-cells improves glucose tolerance reduces inflammation, interpretation these data have been complicated by recent observation that alone obesity-induced inflammation dysregulation, leaving issue effects cell depletion unresolved. To address this question, CD1d null mice (CD1d−/−), which lack but a full complement T-cells,...

Abstract This paper examines if and how temporary migration increases the risk for HIV/STDs in China. Results suggest that migrants had significantly higher prevalence of HIV-risk sexual drug using behaviours but no significant differences were found between non-migrants HIV/STDs. Employing logistic regression analysis, we examined three mechanisms—lax social control, isolation migrant selectivity—by which process may lead to behaviour changes increase migrants’ HIV/STD risks. indicate...

Abstract Nickel (Ni) is an essential micronutrient for higher plants but toxic to at excess levels. Plant species differ extensively mineral uptake and accumulation, these differences often help explain plant tolerances toxicities/deficiencies. Solution culture experiments were conducted under controlled conditions determine the effects of Ni on influx into roots (IN) transport from shoots (TR) zinc (Zn), iron (Fe), copper (Cu), manganese (Mn), calcium (Ca), magnesium (Mg), phosphorus (P),...

Purpose: Major depression disorder (MDD) was associated with inflammatory processes, but association results of syndrome and MDD were inconsistent. To provide more evidence, we measured the plasma levels IL-1β, IL-6, interferon (INT)-α2, INT-γ, tumor necrosis factor (TNF)-α in patients having explored correlations between five proinflammatory cytokines specific depressive symptoms. Patients methods: Plasma concentrations INT-α2, TNF-α using ELISA for 44 54 healthy controls. assessed on...

The present study was carried out to explore the possible relation of plasma plasminogen activator inhibitor-1 (PAI-1), fibrinogen, and factor VII levels other risk factors for coronary heart disease (CHD) serum sex hormone levels. group comprised 48 apparently healthy men. To avoid confounding obesity, correlations were determined in 30 men this with a body mass index (BMI) < 26.4, after controlling age. PAI-1 correlated testosterone, estradiol/testosterone, free testosterone/testosterone...

Abstract Plant tolerance to nickel (Ni) toxicity depends on plant differences for uptake and distribution within tissues. Differences among species Ni tolerance/accumulation might be used identify or develop plants remediation of high soil conditions. Solution culture experiments were conducted under controlled conditions determine influx (IN) into roots, transport (TR) from roots shoots, accumulation in four grown at different levels. White clover (Trifolium repens L.) had dry matter (DM)...

With the rapid growing of older population around world, care for adults is becoming a pressing public health issue. To find optimum and sustainable balance informal formal involvement in senior urgently important. However, it still unclear how adults’ preferences are shaped by range factors at individual country levels. Therefore, present study aimed to examine roles socioeconomic status (SES) culture values old attitude toward care. The data from International Social Survey Program 2012:...

Crohn's disease (CD) is a chronic relapsing form of inflammatory bowel disease, seriously threatening human beings health. However, the pathogenesis CD still unclear and there no specific effective drug for treatment CD. Resina Donis (RD) obtained from Dracaena cochinchinensis (Lour.) S. C. Chen (Liliaceae), has been used clinically. Loureirin B (LB) one most important chemical compositions physiologically active ingredients resina draconis. It molecular structure propan-1-one,...

Abstract Suicidal thoughts and behaviors (STBs) have been associated with emotion dysregulation atypical responses to affective stressful stimuli. To investigate the psychophysiology involved, we measured changes in respiratory sinus arrhythmia (RSA) cardiac pre‐ejection period (PEP; indexing parasympathetic sympathetic functioning, respectively) response stressful‐ sadness‐eliciting laboratory probes. Our sample included adolescents a history of depression STBs ( n = 177), but no 47),...

Previous studies have demonstrated that aging promotes myocardial apoptosis after ischemia/reperfusion, via unknown specific mechanisms. The present study investigates the potential relationship between lncRNAs and aging-related by lncRNA/mRNA microarray technology. results indicate increased lncRNA ENSMUST00000134285 mMAPK11, confirmed both bioinformatics analysis polymerase chain reaction (PCR). Mouse cardiomyocytes were subjected to gene manipulation (ENSMUST00000134285 knockdown...

Abstract Sensorimotor responses vary as a function of the cardiac cycle phase. These effects, known time have been explained by inhibition afferent signals on information processing. However, validity effects is challenged mixed findings. Factors such current processing and affective context may modulate account for inconsistencies in literature. The study examines influence threatening stimuli two aspects sensorimotor processing, response speed inhibition. Thirty‐four participants (M age =...

Abstract The processing of reaction time (RT) stimulus is modulated by its timing relative to the cardiac cycle. RT also influenced task‐irrelevant stimuli: a sensory speeds when it accompanies cue react in another modality. Different theories have been proposed explain this accessory effect (ASE). However, unclear whether ASE interacts with effect. In present study, relationship ASE, timing, and valence was examined. Fifty‐two subjects performed 400 trials simple task. Images neutral fear...

Autism spectrum disorder (ASD) is a neurodevelopmental that influences an individual’s cognitive functions and social interaction. While most studies have focused on children adolescents diagnosed with ASD, elevated levels of autistic traits in subclinical populations may also influence individuals’ daily functioning. Autistic are linked to the Big Five personality. In particular, neuroticism (emotion instability) has been shown be positively associated traits, which contribute behavioral...

Abstract Respiratory sinus arrhythmia (RSA) is an index of parasympathetic nervous system activity reflecting respiratory influences on heart rate. This influence typically measured as high frequency rate variability (HF‐HRV) or root mean square successive differences (RMSSD) adjacent inter‐beat intervals. Examining the long‐term stability its measurement important levels resting RSA have been conceptualized a marker individual differences; in particular, individual's autonomic regulation...

Background: Depression has been shown to have adverse effects on blood pressure (BP) and is associated with high variability (BPV). In turn, short-term BPV related eventual cardiovascular risk. But it not clear how early in adulthood the detrimental of depression may be discerned, if being at risk for also compromises BPV, whether clinical features moderate its effects. We investigated these three issues among young adults using an office-like setting. Methods: total, 218 subjects a history...

Background: Cardiovascular disease (CVD) is the leading cause of mortality and disability worldwide. While sex differences in CVD have been well documented, physiological mechanisms those remain unclear. As important components cardiovascular system, cardiac vagal control baroreflex serve as are modifiable factors for gender-specific preventions. Methods: Ninety-four healthy adults (18–44 years age; Mage = 21.09 years; 46 female) were recruited to complete assessments heart rate variability...

Summary Female entertainment workers (FEWs) in China are at increased risk of HIV and other sexually transmitted infections, but correlates their risky sexual behaviour remain poorly understood. Using data from a series four surveys, this paper employs repeated measures analysis to identify individual social consistent condom use among FEWs Shanghai. Results reveal that both cognitive influence factors statistically significant bivariate relationships with stable or non-stable partner; only...

Abstract Depression has been associated with high blood pressure (BP). However, the mechanisms of relation between depression and BP are unclear. We therefore examined whether impaired cardiac vagal control, indexed as low levels resting respiratory sinus arrhythmia (RSA), serves a route from to BP. The sample included 125 subjects histories (probands), 123 never depressed siblings probands (high‐risk siblings), 156 controls. Resting RSA was assessed at Time 1 (T1) along when were...