A5008558101- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- GDF15 and Related Biomarkers
- Macrophage Migration Inhibitory Factor
- Cerebrovascular and Carotid Artery Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Health and Mental Health
- Inflammasome and immune disorders
- Acute Ischemic Stroke Management
- Nutrition and Health in Aging
- Nuclear Receptors and Signaling
- Atherosclerosis and Cardiovascular Diseases
- Intracranial Aneurysms: Treatment and Complications
- Cardiovascular Health and Disease Prevention
- Vascular Procedures and Complications
- Heart Rate Variability and Autonomic Control
Semmelweis University
2022-2025
Age-related disorders are closely linked to the accumulation of senescent cells. The senescence-associated secretory phenotype (SASP) sustains and progresses chronic inflammation, which is involved in cellular tissue dysfunction. SASP-related growth differentiation factor-15 (GDF-15) an immunoregulatory cytokine that coupled aging thus may have a regulatory role development maintenance atherosclerosis, major cause cardiovascular disease (CVD). Although effects GDF-15 tissue-specific...
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide, atherosclerosis key factor promoting its development. Carotid intima-media thickening presence carotid plaques are important indices cardiovascular risk. In addition, inflammation a major complex in development atherosclerosis. The relationships between certain inflammatory markers have rarely been studied healthy individuals. Therefore, we aimed to investigate associations subclinical various biomarkers...
Background: To investigate the geometry of aortoiliac (AI) segment and its correlation with sex, age, cardiovascular (CV) risk factors. Methods: Abdominal pelvic CTA/MRA scans 204 subjects (120 males; median age: 53 [IQR, 27–75] years) without AI steno-occlusive disease or scoliosis were retrospectively analyzed. The participants enrolled consecutively, ensuring representation each age decade. An in-house written software was developed to assess elongation using tortuosity index (TI)...
Background: Depression has been shown to have adverse effects on blood pressure (BP) and is associated with high variability (BPV). In turn, short-term BPV related eventual cardiovascular risk. But it not clear how early in adulthood the detrimental of depression may be discerned, if being at risk for also compromises BPV, whether clinical features moderate its effects. We investigated these three issues among young adults using an office-like setting. Methods: total, 218 subjects a history...
The aim was to evaluate the outcome of stenting in patients with isolated distal internal carotid artery (ICA) stenosis or post-surgical restenosis, as no data are currently available literature. Sixty-six (men, N = 53; median age: 66 [IQR, 61-73] years) ≥50% ICA (re)stenosis were included this single-center retrospective study. narrowest part at least 20 mm from bifurcation all patients. Patients divided into two etiological groups, atherosclerotic (AS, 40) and restenotic (RES, 26)....
Abstract Growth and differentiation factor-15 (GDF-15) is a stress-associated cytokine of the transforming growth factor-β superfamily. The inflammatory angiogenic effects GDF-15 in atherosclerosis are controversial, its correlation with long asymptomatic phase disease not well understood. Coronary artery calcium score (CACS) ankle-brachial index (ABI) sensitive markers subclinical atherosclerosis. To date, only few studies have examined impact on coronary calcification, association between...
to investigate the effects of vessel geometry on steno-occlusive and dilatative common iliac artery (CIA) pathologies.