A5025296141- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Cytomegalovirus and herpesvirus research
- HIV-related health complications and treatments
- Syphilis Diagnosis and Treatment
- Gestational Diabetes Research and Management
- Toxoplasma gondii Research Studies
- Public Health and Social Inequalities
- Herpesvirus Infections and Treatments
- HIV, Drug Use, Sexual Risk
- Parvovirus B19 Infection Studies
- Reproductive tract infections research
- Mosquito-borne diseases and control
- Pediatric health and respiratory diseases
- Pregnancy and preeclampsia studies
- Innovation and Socioeconomic Development
- Child Nutrition and Water Access
- Respiratory viral infections research
- Pneumocystis jirovecii pneumonia detection and treatment
- Parasitic Infections and Diagnostics
- Maternal and Neonatal Healthcare
- Adolescent Sexual and Reproductive Health
- Latin American socio-political dynamics
- Heme Oxygenase-1 and Carbon Monoxide
Ministerio de Salud
2024
Ministerio de Salud - Provincia de Buenos Aires
2021
Ministerio de Salud
2021
Infant Foundation
2012-2018
AIDS Clinical Trials Group
2016
National Institutes of Health
2016
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2016
Universidade Federal de São Paulo
2014
Hospital Nossa Senhora da Conceição
2012
Fundação Oswaldo Cruz
2012
The safety and efficacy of adding antiretroviral drugs to standard zidovudine prophylaxis in infants mothers with human immunodeficiency virus (HIV) infection who did not receive antenatal therapy (ART) because late identification are unclear. We evaluated three ART regimens such infants.
Untreated syphilis during pregnancy is associated with spontaneous abortion, stillbirth, prematurity and infant mortality. Syphilis may facilitate HIV transmission, which especially concerning in low- middle-income countries where both diseases are common.
Sexually transmitted infections (STIs) in pregnancy such as Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) may lead to adverse infant outcomes.Individual urine specimens from HIV-infected pregnant women diagnosed with HIV during labor were collected at the time of birth tested by polymerase chain reaction for CT NG. Infant infection was determined 3 months morbidity/mortality assessed through 6 months.Of 1373 maternal samples, 277 (20.2%) positive and/or NG; 249 (18.1%) CT, 63...
Background Sexually transmitted infections (STIs) including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP), and cytomegalovirus (CMV) may lead to adverse pregnancy infant outcomes. The role of combined maternal STIs in HIV mother-to-child transmission (MTCT) was evaluated mother-infant pairs from NICHD HPTN 040. Methodology Urine samples HIV-infected pregnant women during labor were tested by polymerase chain reaction (PCR) for CT, NG, CMV. Infant infection...
Background: Congenital cytomegalovirus (CMV) infection (cCMV) is an important cause of hearing loss and cognitive impairment. Prior studies suggest that HIV-exposed children are at higher risk acquiring cCMV. We assessed the presence, magnitude factors associated with cCMV among infants born to HIV-infected women, who were not receiving antiretrovirals during pregnancy. Methods: urinary CMV load determined in a cohort women Neonatal urines obtained birth tested for DNA by qualitative reflex...
ObjectivesTo evaluate whether maternal HIV disease severity during pregnancy is associated with an increased likelihood of lower respiratory tract infections (LRTIs) in HIV-exposed, uninfected infants.MethodsHIV-exposed, uninfected, singleton, term infants enrolled the NISDI Perinatal Study, birth weight >2500 g were followed from until 6 months age. LRTI diagnoses, hospitalizations, and factors assessed.ResultsOf 547 infants, 103 (18.8%) experienced 116 episodes (incidence = 0.84 LRTIs/100...
Cytomegalovirus (CMV) urinary shedding in pregnant women infected with human immunodeficiency virus (HIV) was evaluated to determine whether it poses an increased risk for congenital CMV infection (cCMV).A subset of mother-infant pairs enrolled the perinatal NICHD HPTN 040 study (distinguished by no antiretroviral use before labor) evaluated. Maternal and infant urines were tested qualitative real-time polymerase chain reaction (RT-PCR) DNA quantitative RT-PCR performed on positive...
Objective To report emerging data on the use of highly active antiretroviral therapy (HAART) in Argentina by assessing patterns HAART access and late vs early treatment initiation a population‐based cohort adults infected with HIV type‐1. Design The Prospective Study Use Monitoring Antiretroviral Therapy (PUMA) is study 883 HIV‐positive individuals enrolled Argentinean drug program. Individuals were 16 years age older recruited from 10 clinics across Argentina. Methods Sociodemographic...
To describe laboratory abnormalities among HIV-infected women and their infants with standard increased lopinavir/ritonavir (LPV/r) dosing during the third trimester of pregnancy.We evaluated data on pregnant from NISDI cohorts (2002-2009) enrolled in Brazil, who received at least 28 days LPV/r pregnancy gave birth to singleton infants.164 [(798/198 or 800/200 mg/day) (Group 1)] 70 [(> 2)]. Group 1 was more likely have advanced clinical disease use ARVs for treatment, less CD4 counts > 500...
The standard prophylactic regimen used as antiretroviral therapy (ART) for infants born to mothers in high-income and middle-income countries who are infected with human immunodeficiency virus (HIV) infection has been a 6-week course of zidovudine. Randomized controlled trials investigating postexposure prophylaxis late-presenting women HIV did not receive ART pregnancy have conducted breast-fed populations but non–breast-fed populations. Several showed that combination (zidovudine plus ≥1...
More than 62,000 individuals are currently on antiretroviral treatment within the public health system in Argentina. In 2019, more 50% of people ART received non-nucleoside reverse transcriptase inhibitors (NNRTIs). this context, second nationwide HIV-1 pretreatment drug resistance surveillance study was carried out between April and December 2019 to assess prevalence Argentina using World Health Organization guidelines. This a cross-sectional enrolling consecutive 18-year-old older starting...
El dengue, una enfermedad viral transmitida por mosquitos del género Aedes, está emergiendo como un desafío significativo de salud pública en muchas partes mundo, incluida la Argentina. dengue perinatal se refiere a transmisión virus madre al feto durante el embarazo o parto. Si bien ha prestado atención impacto población general, su efecto período sido menos estudiado y comprendido. En este artículo exponen conceptos centrales perinatal, sus implicaciones para materna neonatal las...
Durante más de cuatro décadas se ha generado evidencia científica suficiente para comprender los mecanismos involucrados en la transmisión vertical (TV) del VIH, lo que permitido diseñar las intervenciones que, al día hoy, lograron avances sustanciales prevención nuevos casos. Estas intervenciones, basadas científica, abarcan tanto gestación y el parto como cuidado las/los expuestos perinatales (1). Además, existen algunos paradigmas asociados a TV VIH han orientado todas recomendaciones...
OBJECTIVES: To describe laboratory abnormalities among HIV-infected women and their infants with standard increased lopinavir/ritonavir (LPV/r) dosing during the third trimester of pregnancy. METHODS: We evaluated data on pregnant from NISDI cohorts (2002-2009) enrolled in Brazil, who received at least 28 days LPV/r pregnancy gave birth to singleton infants. RESULTS: 164 [(798/198 or 800/200 mg/day) (Group 1)] 70 [(> 2)]. Group 1 was more likely have advanced clinical disease use ARVs for...
Una de las variables para medir la calidad vida personas que viven con el virus inmunodeficiencia humana (VIH) es trabajo. El objetivo este estudio fue comparar, discriminando por género, situación laboral VIH en Buenos Aires, Argentina. Es un comparativo realizado tres hospitales entre abril y julio 2015. Se evaluó: rango edad, tratamiento antirretroviral, carga viral, a cargo, autopercepción del estado salud, nivel educativo, laboral, acceso beneficio social, comparación ingresos salario...