Henry Akpan

ORCID: 0000-0003-2364-1647
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About
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Research Areas
  • Natural Antidiabetic Agents Studies
  • Drug-Induced Hepatotoxicity and Protection
  • Viral Infections and Outbreaks Research
  • Viral Infections and Vectors
  • Liver Disease Diagnosis and Treatment
  • Influenza Virus Research Studies
  • Vaccine Coverage and Hesitancy
  • Phytochemistry and biological activity of medicinal plants
  • Phytochemicals and Medicinal Plants
  • Heavy Metal Exposure and Toxicity
  • COVID-19 epidemiological studies
  • Global Maternal and Child Health
  • Food Chemistry and Fat Analysis
  • Viral gastroenteritis research and epidemiology
  • Insect Pest Control Strategies
  • Diet, Metabolism, and Disease
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Pancreatic function and diabetes
  • Coconut Research and Applications
  • Medicinal Plants and Neuroprotection
  • Advanced Glycation End Products research
  • Papaya Research and Applications
  • Erythropoietin and Anemia Treatment
  • Environmental and Social Impact Assessments

University of Uyo
2012-2025

Bowen University
2024

Olabisi Onabanjo University
2018

Federal Ministry of Health
2010-2015

In May 2010, a team of national and international organizations was assembled to investigate children's deaths due lead poisoning in villages northwestern Nigeria.Our goal determine the cause childhood outbreak, risk factors for child mortality, identify children < 5 years age need emergency chelation therapy poisoning.We administered cross-sectional, door-to-door questionnaire two affected villages, collected blood from 2-59 months age, obtained soil samples family compounds. Descriptive...

10.1289/ehp.1103965 article EN public-domain Environmental Health Perspectives 2011-12-20

Background In 2010, Médecins Sans Frontières (MSF) discovered extensive lead poisoning impacting several thousand children in rural northern Nigeria. An estimated 400 fatalities had occurred over 3 mo. The US Centers for Disease Control and Prevention (CDC) confirmed widespread contamination from lead-rich ore being processed gold, environmental management was begun. MSF commenced a medical programme that included treatment with the oral chelating agent 2,3-dimercaptosuccinic acid (DMSA,...

10.1371/journal.pmed.1001739 article EN cc-by PLoS Medicine 2014-10-07

Immunization is a cost-effective public health intervention to reduce morbidity and mortality associated with infectious diseases. The Nigeria Demographic Health Survey of 2008 indicated that only 5.4% children aged 12-23 months in Bungudu, Zamfara State were fully immunized. We conducted this study identify the determinants routine immunization coverage community.

10.11694/pamj.supp.2014.18.1.4149 article EN PubMed 2014-01-01

Diabetes is a persisting and deadly disease which occur due to pancreatic dysfunction resulting in decrease or lack of insulin production. This study investigated the therapeutic potential Gongronema latifolium (GL) Ocimum gratissimum (OG) on liver kidney functions alloxan-induced diabetic rats exposed 1.0 ml/kg/bw carbon tetrachloride (CCl4), intraperitonially. Forty-five (45) divided into 9 groups 5 each were used. Groups 1, 2 3 respectively normal control (NC), (DC) CCl4 (DCCl4) 14th day....

10.9734/ajarr/2025/v19i1868 article EN Asian Journal of Advanced Research and Reports 2025-01-10

The protective effect of vitamins C and E against gasoline vapor-induced liver injury was investigated in rats. Liver assessed from the activities function diagnostic indices including serum alanine aminotransferase (ALT), aspartate (AST), gamma glutamyl transferase (\gamma-GT), alkaline phosphatase (ALP) activities, total protein (TSP), albumin concentrations, histological architectures tissues experimental animals. results showed that vapors caused a significant (P = 0.05) higher than...

10.3906/biy-1004-111 article EN TURKISH JOURNAL OF BIOLOGY 2012-01-01

Influenza surveillance data from tropical, sub-Saharan African countries are limited. To better understand the epidemiology of influenza, Nigeria initiated influenza in 2008.Outpatients with influenza-like illness (ILI) and inpatients severe acute respiratory (SARI) were enrolled at 4 sentinel facilities. Epidemiologic obtained, specimens tested for viruses, using real-time reverse-transcription polymerase chain reaction assays.During April 2009-August 2010, 2841 patients enrolled. Of 2803...

10.1093/infdis/jis584 article EN The Journal of Infectious Diseases 2012-11-20

Introduction: Immunization is a cost-effective public health intervention to reduce morbidity and mortality associated with infectious diseases. The Nigeria Demographic Health Survey of 2008 indicated that only 5.4% children aged 12-23 months in Bungudu, Zamfara State were fully immunized. We conducted this study identify the determinants routine immunization coverage community.

10.11604/pamjs.supp.2014.18.1.4149 article EN cc-by Pan African Medical Journal 2014-01-01

Introduction: Immunization is a cost-effective public health intervention to reduce morbidity and mortality associated with infectious diseases. The Nigeria Demographic Health Survey of 2008 indicated that only 5.4% children aged 12-23 months in Bungudu, Zamfara State were fully immunized. We conducted this study identify the determinants routine immunization coverage community.

10.11604/pamj.supp.2014.18.1.4149 article EN cc-by Pan African Medical Journal 2014-01-01

Abstract Using questionnaires and serologic testing, we evaluated bat lyssavirus exposure among persons in an area of Nigeria that celebrates a festival. Bats from festival caves underwent testing for phylogroup II lyssaviruses (Lagos virus, Shimoni Mokola virus). The enrolled households consisted 2,112 persons, whom 213 (10%) were reported to have ever had contact (having touched bat, having been bitten by or scratched bat) 52 (2%) bat. Of 203 participants with contact, 3 (1%) received...

10.3201/eid2607.191016 article EN cc-by Emerging infectious diseases 2020-06-09

Potential role of Nutraceuticals In Present Scenerio: A ReviewRahul dev, Sunil kumar, Jagbir singh, Bhupendra chauhan

10.7324/japs.2015.50314 article EN cc-by Journal of Applied Pharmaceutical Science 2015-01-01

The effect of Nauclea latifolia, a promising vegetable used in the traditional management metabolic disorders on some biochemical assay was investigated diabetic rat.The study design consisted twenty four rats divided into groups six each.Whereas 1 and 2, non controls received placebo treatment, 3 200mg/kg b.w. latifolia twice day while 4 th group subcutaneous insulin, 5IU/kg per day, for 21 days.Thereafter, animals were sacrificed, their serum to lipid components liver function enzymes,...

10.14303/jmms.2014.033 article EN International Research Journal of Medicine and Medical Sciences 2015-01-01

The physical and chemical properties of the oil extracted from six (6) varieties coconut fruits were determined. oils brownish, some yellowish when melted, at times white solidified. had specific gravity ranging between 0.90 0.92. yield (% contents) ether extract was also analyzed using soxhlet extraction technique. results showed contents 88.54% in dry samples 69.14% fresh samples. Result findings a higher percentage saturated fatty acid content across entire (88.5±0.85% 97.0±0.37%)...

10.3923/pjn.2006.106.109 article EN Pakistan Journal of Nutrition 2006-02-15

Phenytoin is known to induce microsomal enzymes including xanthine oxidase which catalyzes uric acid synthesis with superoxides as byproducts, thus contributing the oxidative stress of phenytoin hepatotoxicity. To investigate role antioxidant vitamins in ameliorating induced hepatic changes through possible actions on activities measured by urate concentration. Growing albino rats Wistar strain were randomly divided into 8 groups 7 each. Group 2, 3, 4, 5, 6, and treated alone, + folic acid,...

10.3923/pjbs.2014.1179.1184 article EN Pakistan Journal of Biological Sciences 2014-09-22

Abstract Context: Population-specific attributes typically determine the behavior of human genotypes and traits in individuals. Examining genetic relationships between populations presents an opportunity to observe patterns changes over time. By comparing populations, it is possible see factors that may have sparked evolution a trait or genotype as well diversity populations. Genetic groups Nigeria still largely undefined. This can be achieved with use markers. Aims: To Igbo, Ibibio, Yoruba,...

10.4103/njbcs.njbcs_68_24 article EN cc-by-nc-sa Nigerian Journal of Basic and Clinical Sciences 2024-10-29
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