A5044597949- Polyomavirus and related diseases
- Full-Duplex Wireless Communications
- Energy Harvesting in Wireless Networks
- Plant Virus Research Studies
Helsinki University Hospital
2017-2018
University of Helsinki
2017-2018
BK polyomavirus (BKPyV) infection is a common asymptomatic viral in the general population. Severe complications are seen immunocompromised individuals, such as polyomavirus-associated nephropathy (PyVAN) renal transplant recipients. Information on BKPyV microRNA expressions scarce, although polyomavirus-encoded microRNAs have been shown to control replication and assist immune evasion. Whereas pathogenic role of rearrangements JC has well established, little known about PyVAN. To assess...
Progressive multifocal leukoencephalopathy (PML) is a fatal disease caused by reactivation of JC polyomavirus (JCPyV) in immunosuppressed individuals and lytic infection neurotropic JCPyV glial cells. The exact content mutations within individual strains has not been studied to our knowledge.We exploited the capacity single-molecule real-time sequencing technology determine sequence complete genomes single reads. method was used precisely characterize 3 patients with PML without bias...
JC polyomavirus (JCPyV) is reactivated in approximately 20% of renal transplant recipients, and it may rarely cause JCPyV-associated nephropathy (JCPyVAN). Whereas progressive multifocal leukoencephalopathy the brain caused by rearranged neurotropic JCPyV, little known about viral sequence variation JCPyVAN owing to rarity this condition.Using single-molecule real-time sequencing, characterization full-length JCPyV genomes urine plasma samples from 1 patient with 20 stable recipients viruria...