- Bariatric Surgery and Outcomes
- Gut microbiota and health
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Dietary Effects on Health
- Body Contouring and Surgery
- Organ Transplantation Techniques and Outcomes
- Obesity, Physical Activity, Diet
- Eating Disorders and Behaviors
- Proteoglycans and glycosaminoglycans research
- Reproductive Biology and Fertility
- Liver Disease and Transplantation
- Nutritional Studies and Diet
- Ovarian function and disorders
- Consumer Attitudes and Food Labeling
- Protein Hydrolysis and Bioactive Peptides
- Circadian rhythm and melatonin
- Obesity and Health Practices
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Coccidia and coccidiosis research
- Venomous Animal Envenomation and Studies
- Intensive Care Unit Cognitive Disorders
- Menopause: Health Impacts and Treatments
- Developmental Biology and Gene Regulation
Universidade de São Paulo
2013-2025
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2022-2025
Universidade Federal de São Carlos
2001
Abstract Overweight and obesity are closely linked to gut dysbiosis/dysmetabolism disrupted De‐Ritis ratio [aspartate aminotransferase (AST)/alanine (ALT) ratio], which may contribute chronic noncommunicable diseases onset. Concurrently, extensive research explores nutraceuticals, health‐enhancing supplements, for disease prevention or treatment. Thus, sedentary overweight volunteers were double‐blind randomized into two groups: Novel Nutraceutical_(S) (without silymarin) Nutraceutical (with...
Abstract Nutraceutical interventions supporting microbiota and eliciting clinical improvements in metabolic diseases have grown significantly. Chronic stress, gut dysbiosis, metainflammation emerged as key factors intertwined with sleep disorders, consequently exacerbating the decline quality of life. This study aimed to assess effects two nutraceutical formulations containing prebiotics (fructooligosaccharides (FOS), galactooligosaccharides (GOS), yeast β-glucans), minerals (Mg, Se, Zn),...
ABSTRACT This study explores the effects of a nutraceutical blend with prebiotics, β‐glucans, essential minerals, and silymarin on gut microbiota, inflammation, sleep quality in obesity through microbiota reshaping metabolic improvements over 90 days. A double‐blind, randomized trial was conducted 77 participants divided into two groups receiving either standard (NSupple) or silymarin‐enriched (NSupple_ Silybum ). Fecal plasma samples were collected at baseline post‐supplementation for...
<b><i>Background:</i></b> ADAMTS are metalloproteases with disintegrin and thrombospondin motifs. They secreted proteases playing a role in biological processes such as inflammation, angiogenesis, urogenital development. have specific substrates, the proteoglycans (PG) versican, aggrecan, brevican. Despite data indicating of tumor invasion metastases, effects played by these molecules cancer progression still controversial. In ovarian cancer, importance gene mutations...
The pre-transplant period is complex and includes lots of procedures. severity liver disease predisposes to a high number hospitalizations costs Economic evaluation studies are important tools handle on the waiting list for transplantation.The objective present study was evaluate total cost patient transplantation main resources related higher costs.A in cohort 482 patients registered carried out. In 24 months follow-up, we evaluated all materials, medicines, consultations, procedures,...
We followed polycystic ovary syndrome (PCOS) women with metabolic (MS) over a six-year treatment period and evaluated the influence of PCOS phenotypes on MS risk for type 2 diabetes mellitus (T2DM).
The aim of this study was to evaluate the effectiveness cognitive behavioral therapy in treatment vasomotor, sexual dysfunction, and recurrent depression postmenopausal women.
The increasing burden of obesity generates significant socioeconomic impacts for individuals, populations, and national health systems worldwide. literature on cost-effectiveness obesity-related interventions prevention treatment moderate to severe indicate that bariatric surgery presents high costs associated with effectiveness in improving status referring certain outcomes; however, there is a lack robust evidence at an individual-level estimation its multiple outcomes related...
Studying the dietary habits and symptoms of postmenopausal women during situations such as COVID-19 pandemic is important to mitigate long-term post-pandemic health problems. We compared menopausal food consumption in before pandemic. A longitudinal survey was conducted on Brazilian between 2018 2021. The Kupperman-Blatt Menopausal Index, Women's Health Questionnaire, 24 h recall were used. Of 274 women, 78 (28.5%) participated study intensity lower than previous period (p < 0.05). Energy...
Stress, unhealthy lifestyle, and sleep disturbance worsen cognitive function in mood disorders, prompting a rise the development of integrative health approaches. The recent investigations gut–brain axis field highlight strong interplay among microbiota, inflammation, mental health. Thus, this study aimed to investigate new nutraceutical formulation comprising prebiotics, minerals, silymarin’s impact on mood, quality. evaluated LL1 + silymarin capsule supplementation over 180 days overweight...
Analyze clinical factors and non-oncological gynecological diagnoses before during the initial months of COVID-19 pandemic.
Ovarian cryopreservation is a promising technique despite being hindered by damage from freezing and thawing. Melatonin can mitigate this outcome.