A5087216320- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Cerebral Venous Sinus Thrombosis
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Soft tissue tumor case studies
- Ocular Oncology and Treatments
- Metabolism, Diabetes, and Cancer
- Ocular Surface and Contact Lens
- Health Literacy and Information Accessibility
- Facial Trauma and Fracture Management
- Mobile Health and mHealth Applications
- Retinal and Optic Conditions
- Adipose Tissue and Metabolism
- Retinopathy of Prematurity Studies
- Corneal Surgery and Treatments
- Neurological Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Proteoglycans and glycosaminoglycans research
- Retinal and Macular Surgery
- Ophthalmology and Eye Disorders
Duke University
2009-2021
Duke University Hospital
2021
Duke Medical Center
2016-2020
Eye Center
2020
University of Washington
2013-2016
Beijing Anzhen Hospital
2016
Capital Medical University
2016
Research to Prevent Blindness
2016
Cancer Research And Biostatistics
2015
University of Washington Medical Center
2013
Purpose To investigate optic disc perfusion differences in normal, primary open-angle glaucoma (POAG), and normal tension (NTG) eyes using optical microangiography (OMAG) based coherence tomography (OCT) angiography technique. Design Cross-sectional, observational study. Subjects Twenty-eight 30 POAG, 31 NTG subjects. Methods One eye from each subject was scanned with a 68 kHz Cirrus HD-OCT 5,000-based OMAG prototype system centered at the nerve head (ONH) (Carl Zeiss Meditec Inc, Dublin,...
To investigate the differences of perfusion in optic nerve head (ONH) between normal and glaucomatous eyes using optical microangiography (OMAG) based coherence tomography (OCT) angiography technique.One eye from each subject was scanned with a 68 kHz Cirrus 5000 HD-OCT-based OMAG prototype system centered at ONH (Carl Zeiss Meditec Inc, Dublin, CA, USA). Microvascular images were generated dataset by detecting OCT signal consecutive B-scans. The pre-laminar layer (preLC) isolated...
Intraocular pressure (IOP) reduction is key to controlling primary open angle glaucoma (POAG). Pharmacotherapies for POAG or ocular hypertension (OHT) commonly lower IOP by increasing uveoscleral outflow decreasing aqueous humor production. Netarsudil (Rhopressa), a Rho kinase inhibitor, reduces improving trabecular facility, which reduced in POAG. We investigated the effects of netarsudil on dynamics patients with OHT.Double-masked, randomized, vehicle-controlled, Phase 2 trial.Netarsudil...
Optical coherence tomography angiography (OCTA) has increasingly become a clinically useful technique in ophthalmic imaging. We evaluate the repeatability and reproducibility of blood perfusion optic nerve head (ONH) measured using optical microangiography (OMAG)-based OCTA. Ten eyes from 10 healthy volunteers are recruited scanned three times with 68-kHz Cirrus HD-OCT 5000-based OMAG prototype system (Carl Zeiss Meditec Inc., Dublin, California) centered at ONH involving two separate visits...
The ubiquitously expressed G protein α-subunit s α is required for receptor-stimulated intracellular cAMP responses and an important regulator of energy glucose metabolism. We have generated skeletal muscle-specific α-knockout (KO) mice (MGsKO) by mating α-floxed with muscle creatine kinase-cre transgenic mice. MGsKO had normal body weight composition, their serum glucose, insulin, free fatty acid, triglyceride levels were similar to that controls. However, intolerant despite the fact...
Purpose: To determine the utility of tear film cytokines as biomarkers for early primary open-angle glaucoma (POAG). Methods: Patients without POAG and eye drop-naïve patients with newly diagnosed were recruited from an academic hospital-based practice. Tear films obtained analyzed using a multiplex, high-sensitivity electrochemiluminescent enzyme-linked immunosorbent assay proinflammatory (IFNγ, IL-10, IL-12p70, IL-13, IL-1β, IL-2, IL-4, IL-6, IL-8, TNFα). Results: Mean concentrations lower...
BACKGROUND AND OBJECTIVE: Porous anophthalmic orbital implants are used widely. This study evaluates risk factors for porous implant complications and compares complication rates of hydroxyapatite, polyethylene, polyglactin mesh-wrapped aluminum oxide implants. PATIENTS METHODS: The records 105 patients (110 eyes) who received any indication were reviewed retrospectively. Complications recorded correlated with potential factors, including material. All patient de-identified to protect...
To determine whether surgical warm-up affects cataract surgery complication rates and case times.University of Washington Medicine Eye Institute, Harborview, Seattle, Washington, USA.Retrospective case-control study.Patients who had phacoemulsification from June 2010 to December 2011 were consecutively reviewed. Case order for each surgeon was evaluated, comparing intraoperative times attending resident surgeons the first day (considered case) versus subsequent cases. Simple (AMA Current...
<h3>Importance</h3> The perception of being treated with respect by clinicians may be a driver disparities in individuals racial and ethnic minoritie groups eye diseases. Understanding these drivers help identify potential interventions to reduce health prevent vision loss blindness. <h3>Objective</h3> To evaluate the association between minority status clinicians. <h3>Design, Setting, Participants</h3> This cross-sectional analysis nationally representative cohort study using data from...
A 16-year-old girl with worsening vision, new OD visual field deficits, and tumor in right orbital apex underwent biopsy surgical excision. Orbital imaging revealed an apical causing bony erosion. Histopathology confirmed the diagnosis of nodular fasciitis. This is a rare diagnosis, one that can mimic neoplastic process. To authors' knowledge, this first case fasciitis deep orbit optic neuropathy.
To describe a case of anterior ischemic optic neuropathy as presenting sign granulomatosis with polyangiitis.A previously healthy 50-year-old female developed right eye, then left redness and pruritis was diagnosed allergic versus viral conjunctivitis. Five days later, she noted an acute decline in vision the corresponding decrease on Snellen testing from 20/30 to 20/100 correction. She have relative afferent pupillary defect, 2+ pallid disc edema, OCT (Spectralis, Heidelberg Engineering,...