A5082096434- Acute Ischemic Stroke Management
- Antiplatelet Therapy and Cardiovascular Diseases
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Atrial Fibrillation Management and Outcomes
- Geriatric Care and Nursing Homes
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
- Healthcare cost, quality, practices
- Plant Pathogens and Fungal Diseases
- Neurological Disorders and Treatments
- Tryptophan and brain disorders
- Retinal and Optic Conditions
- Dementia and Cognitive Impairment Research
- Oral and Maxillofacial Pathology
- Neurosurgical Procedures and Complications
- Stroke Rehabilitation and Recovery
- Grief, Bereavement, and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Neuroinflammation and Neurodegeneration Mechanisms
- Clinical Laboratory Practices and Quality Control
- Identification and Quantification in Food
Hamad Medical Corporation
2019-2025
Murdoch University
2009-2024
University of Saskatchewan
2014-2024
VA Maryland Health Care System
2020-2024
University of Maryland, Baltimore
2020-2024
University of Utah
2020-2024
Michigan State University
2020-2021
University of Nebraska at Kearney
1996-2020
University of California, Davis
2013-2020
Kearney Agricultural Research and Extension Center
2020
Until dementias can be prevented or cured, interventions that maintain maximize cognitive and functional abilities will remain critical healthcare research priorities. Best practice guidelines suggest individualized exercise programs may improve fitness, cognition, function for people with mild to moderate dementia; however, few high quality intervention trials exist this population. Increasingly, telehealth is being used the delivery availability of services individuals living in rural...
Background Posterior cerebral circulation ischemic stroke (PCS) comprises up to 25% of all strokes. It is characterized by variable presentation, leading misdiagnosis and morbidity mortality. We aim describe PCS in large multiethnic cohorts. Methods A retrospective review a national database from its inception on the 1st January 2014 till 31 December 2020. Incidence per 100,000 adult population/year, demographics, clinical features, location, outcomes were retrieved. divided cohort into...
Abstract Heart failure with preserved ejection fraction (HFpEF) has been characterized by lower blood flow to exercising limbs and peak oxygen utilization (), possibly associated disease‐related changes in sympathetic (α‐adrenergic) signaling. Thus, seven patients HFpEF (70 ± 6 years, 3 female/4 male) controls (CON) (66 male), we examined (%Δ) leg (LBF, Doppler ultrasound) intra‐arterial infusion of phentolamine (PHEN, α‐adrenergic antagonist) or phenylephrine (PE, α 1 ‐adrenergic agonist)...
Aspiration pneumonia is a common complication post-stroke that increases the patient's duration of stay in hospital, mortality and morbidity. We examined incidence, clinical characteristics outcomes among ischaemic stroke-related aspiration patients Qatar. The Qatar Stroke database was reviewed for with acute stroke admitted to Hamad General Hospital, tertiary care medical facility, between January 2014 April 2024. Patients were retrospectively assessed at 90 days, modified Rankin Score days...
ABSTRACT The early developmental stages of haemopoiesis are thought to be regulated by paracrine growth factors and the haemopoietic environment. Are gap junctions involved here? Gap structures in cell membranes allowing direct transfer ions small molecules between adjacent cells known development. We have found that although connexin43 rare (0.00016±0.0002/μm2 tissue) normal adult mouse marrow their expression is 80-fold higher (0.0292±0.0147/μm2) neonatal marrow. One difference tissue...
Antibiotics are among the most common medications prescribed in nursing homes. The annual prevalence of antibiotic use residents homes ranges from 47% to 79%, and more than half courses initiated nursing-home settings unnecessary or inappropriately (wrong drug, dose, duration). Inappropriate is associated with a variety negative consequences including Clostridioides difficile infection (CDI), adverse drug effects, drug–drug interactions, antimicrobial resistance. In response this problem,...
To evaluate if in patients with known diabetes, pretreatment metformin will lead to less severe stroke, better outcome, and lower mortality following acute stroke.
Abstract Background and objectives Hypertriglyceridemia (HT) may increase the risk of stroke. Limited studies have shown that stroke severity infarction size are smaller in patients with HT. We explored relationship between triglyceride levels factors, outcome a large prospective database. Design Prospective Cross-sectional study. Setting retrospectively interrogated Qatar Stroke Database all admitted 2014-2022 acute ischemic evaluated triglyceride, diabetes, (measured on NIHSS), type (TOAST...
California is a major almond (Prunus dulcis) producer in the world. In September 2012, 2-year-old trees from an orchard Fresno Co. with stem cankers were submitted for disease diagnosis. survey of orchard, 12 ha (1,500 Nonpareil and 1,800 Monterey trees) 48 had been killed apparently due to canker. The developed above graft union, covered amber sap, often girdled trunk. Isolations made tissues at canker margins onto acidified potato dextrose agar (PDA) yielded two fungi, Macrophomina...
Fig limb dieback is a cosmopolitan disease caused by Neoscytalidium dimidiatum (Botryosphaeriaceae), characterized branch and shoot cankers, discoloration of woody tissues, dieback. The present study investigated the etiology in California that seems to have become prevalent among fig orchards last several years. During orchard surveys Fresno, Kern, Madera Counties over 3 years, we isolated consistently evaluated pathogenicity N. under laboratory field conditions. effect summer winter...
The relationship between growth and sexual maturation is central to understanding the dynamics of animal populations which exhibit indeterminate growth. In sequential hermaphrodites, undergo post-maturation sex change, size age at change occurs directly affects reproductive output hence population productivity. However, these traits are often labile, may be strongly influenced by heterogenous mortality rates. We analysed otolith microstructure a protandrous (i.e., male-to-female) fish...
Understanding the relationship of COVID-19 to stroke is important. We compare characteristics pre-pandemic historical (Pre-C), cases in acute COVID infection (Active-C) and patients who have recovered from (Post-C).We interrogated Qatar database for all admissions between Jan 2019 Feb 2020 (Pre-C) Active-C (Feb2020-Feb2021) Post-C determine how affected ischemic sub-types, clinical course, outcomes prior to, during post-pandemic peak. used modified Rankin Scale (mRS) measure outcome at...
Introduction Perinatal depression is well recognised as a mental health condition but <50% of cases are identified by healthcare professionals in routine clinical practice. The Edinburgh Postnatal Depression Scale (EPDS) often used to detect symptoms postnatal maternity and child services. National Institute for Health Care Excellence (NICE) recommends 2 ‘ultra-brief’ case-finding questions (the Whooley questions) aid identification during the perinatal period, this recommendation was...
Despite wide excision and post-operative irradiation, loco-regional and/or metastatic recurrence is a significant clinical problem in salivary adenoid cystic carcinoma (SACC). Reliable biomarkers are required to tailor post-treatment surveillance patients at highest risk of recurrence. We sought determine the utility TP53 PIK3CA mutations as prognostic SACC.DNA was extracted from archival tumour blocks 145 SACC 66 UK referral centres sequenced for mutations. Clinical, pathological outcome...
Background Atrial fibrillation is an important risk factor for stroke but there are limited data on atrial fibrillation-related from the Middle East. Methods We interrogated Qatar Stroke Database to establish occurrence, clinical features, and outcomes of at Hamad General Hospital, sole provider acute care in Qatar. Results A total 4079 patients (81.4% male, mean age 55.4 ± 13.3 years) were enrolled database between January 2014 21 October 2017. was present 260 (6.4%) patients, whom 106...
This SHEA white paper identifies knowledge gaps and challenges in healthcare epidemiology research related to coronavirus disease 2019 (COVID-19) with a focus on core principles of epidemiology. These gaps, revealed during the worst phases COVID-19 pandemic, are described 10 sections: epidemiology, outbreak investigation, surveillance, isolation precaution practices, personal protective equipment (PPE), environmental contamination disinfection, drug supply shortages, antimicrobial...
Several reports document a decrease in the rates of stroke hospital admissions during covid-19 pandemic. There is very little information whether admission will change as infection controlled. We report on our before, and following peak infections prospective database from Qatar.
Human B cells stimulated through both their immunoglobulin and CD40 receptors up-regulate 745 +/- 51 interleukin (IL)-13 ligand binding sites with an affinity of 0.91 0.08 nM within 24 h. IL-13 binds primarily to the IL-13Ralpha1 subsequent sequestration IL-4Ralpha into complex. may also be found in those capable IL-4. gamma chain (gammac) participates IL-4 but is not association bound IL-13. Dimeric composed complexed either or gammac occur simultaneously defined cell populations. mRNAs for...
<b><i>Background:</i></b> Sex differences may determine presentation, utility of treatment, rehabilitation, and occurrences major adverse cardiovascular events (MACEs) in acute stroke (AS). <b><i>Objective:</i></b>The purpose the study was to evaluate short-term prognosis long-term outcomes MACEs Qatari nationals admitted with AS. <b><i>Methods:</i></b> All AS patients between January 2014 February 2019 were included. We...
Background and Purpose: Nocturnal non-dipping blood pressure heart rate are associated with an increased risk of cardiovascular disease. The effects such variance on cerebrovascular disease have not been well studied. Methods: 24-h ambulatory (ABPM) were monitored B-pro in patients acute stroke within the initial week hospital admission. factor profiles, clinical presentation, imaging, short-term prognosis compared nocturnal dippers non-dippers (more than 10% decrease) rate. Results: We...