A5089787891- Dialysis and Renal Disease Management
- Systemic Lupus Erythematosus Research
- Blood Pressure and Hypertension Studies
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Chronic Kidney Disease and Diabetes
- Vitamin D Research Studies
- Liver Diseases and Immunity
- Parathyroid Disorders and Treatments
- Acute Kidney Injury Research
- Bone health and osteoporosis research
- Renal Diseases and Glomerulopathies
- Immunodeficiency and Autoimmune Disorders
- Sexual Differentiation and Disorders
- Inflammatory Biomarkers in Disease Prognosis
- Non-Invasive Vital Sign Monitoring
- Magnesium in Health and Disease
- Testicular diseases and treatments
- Pancreatitis Pathology and Treatment
- Potassium and Related Disorders
- Blood properties and coagulation
- Apelin-related biomedical research
- Hormonal Regulation and Hypertension
- Vascular Anomalies and Treatments
Theodor Bilharz Research Institute
2008-2024
Zagazig University
2022
Menoufia University
2020
Pediatric Nephrology of Alabama
2020
Adiponectin (ADPN) levels are consistently elevated among patients with advanced chronic kidney disease, but its relationship cardiovascular outcomes in this population remains controversial. The aim of our study was to measure the plasma ADPN end-stage renal disease on maintenance hemodialysis (HD) and we studied correlates mortality.Our included 133 HD (79 male 54 female patients) a mean age 54.6 ± 17.3 years who had been receiving regular for at least 6 months nephrology units Theodor...
The kidneys are affected in almost all patients with amyloid A secondary amyloidosis (AA) but less frequently immunoglobulin light chains primary systemic (AL) amyloidosis. In this study, we present the incidence, etiology, clinical manifestations, biochemical features and course of renal We conducted a retrospective study on group 40 cases biopsy-proven They constituted 2.5% total biopsies performed Theodor Bilharz Research Institute, Cairo, Egypt, during period from February 2003 to May...
Interleukin-10 (IL-10) is an important immunoregulatory cytokine. There are few studies evaluating the association between IL-10 and lupus nephritis (LN). The aim of this study was to evaluate gene promoter -592 A/C with LN susceptibility.The conducted on 84 patients systemic erythematosus (SLE). Patients were divided into group (Group I, 48 patients) non-LN II, 36 patients). polymorphisms in determined by polymerase chain reaction restriction fragment length polymorphism both groups....
The national committee for control of viral hepatitis (NCCVH) in Egypt, settled by the Ministry health, treated over one million patients around 60 centers with chronological changes drug combinations. This research aims to study health care facilities and services provided NCCVH treatment Egypt explore hinders faced.A cross-sectional operational study. Multistage random sampling technique was applied Egyptian governorates. From each stratum governorate chosen from which center randomly...
Background: Anemia is a major cardiovascular riskfactor in renal disease. It might be appropriate toextrapolate this association of anemia with cardiovasculardisease to transplant recipients who continue tohave significant risk.The aim our study was elucidate the prevalence andrisk factors after kidney transplantation.Methods: We studied 118 stable adult transplantrecipients [age at ranged between 22 and 58,42 12], 74 (62.7%) were males 44 females(37.3%) received allograft December 1998and...
Abstract Background Diabetic nephropathy (DN) is a frequent and long-lasting microvascular consequence that has an established connection with diabetes. It serves as the primary etiological agent of end-stage renal disease, critical disorder develops on worldwide level. The molecular pathophysiology DN multifactorial, such transforming growth factor-beta [TGF-β] which affects expression miRNAs miRNA-21 miRNA-192 during fibrosis. However, to date, clinical application inadequate due...
Secreting vasoactive factors such asadrenomedullin (AM) has been intensivelyinvestigated due to its vascular protective propertiesand promising potential as a therapeutic target. Therelationship between adrenomedullin and type (2)diabetes needs be elucidated it is associatedwith significant elevation in plasma adrenomedullinlevels.The aim of this study was evaluate therole the development ofvasculopathy significance markerdenoting renal affection 2 diabetic patients.Materials Methods: This...
<h3>Background</h3> Lupus nephritis can affect up to 70% of the SLE population elevated serum IL-10 levels were observed in patients and have been shown be associated with disease activity. It enhances B-cell surivival, proliferation, differentiation, Genotypic variations human promoter may account for individual variation production turn, susceptibility a particular disease. <h3>Objectives</h3> investigate -592 A/C polymorphism lupus different pathological classes assess its influence on...
<h3>Background</h3> Defining an early and reliable non invasive biomarker of kidney involvement in SLE is highly desirable. Anti-C1q auto antibodies have been proposed as a useful marker since their occurrence correlates with renal and, possibly, nephritic activity. Interleukin-10 (IL-10), multifunctional cytokine that plays crucial role inflammation the immune system. High IL-10 expression corresponding alleles suggested to play causal or exacerbating SLE. The promoter gene polymorphic,...
Background: The glycation process results in formation of advanced end products (AGEs), which accumulate different organs at an accelerated rate diabetes, resulting alteration both structure and function. This effect is via the receptor for AGES (RAGE), a signaling leading to profibrotic reactions. renin angiotensin aldosterone system (RAAS) activated diabetic nephropathy (DN) leads more renal damage. inhibited by converting enzyme inhibitors (ACEIs) blockers (ARBs) mineralocorticoid...
Worldwide the number of patients requiring chronic hemodialysis (HD) is rapidly growing.Hemodialysis greatly reduces quality life and it associated with extremely high mortality rates.The present study was planned to impact age gender on cardiovascular death markers in a sample Egyptian patients, maintained hemodialysis.In an observational cohort we investigated 70 non-diabetic maintenance (MHD).All were non-diabetics without viral hepatitis, mean 57±7.3.Patients divided into subgroups...
BACKGROUND: Chronic kidney disease-mineral and bone disorder (CKD-MBD) is one of the main culprits increasing morbidity mortality in patients with stage: 3–5 CKD. Association between Vitamin D receptor (VDR) genetic polymorphisms CKD-MBD has been inconsistent. AIM: The aim study was to assess association VDR Taq I (rs731236) Bsm (rs1544410) gene CKD; development progression CKD-MBD. METHODS: Sixty adult (43–56 years.) Egyptian male (CKD stages: estimated glomerular filtration rate <60...