- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Advanced Sensor and Energy Harvesting Materials
- Sulfur-Based Synthesis Techniques
- Tactile and Sensory Interactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Chemical Synthesis and Reactions
- Quinazolinone synthesis and applications
- Text and Document Classification Technologies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Interactive and Immersive Displays
- Concrete and Cement Materials Research
- Machine Learning and Data Classification
- Conducting polymers and applications
- Concrete Properties and Behavior
- Membrane-based Ion Separation Techniques
- Innovative concrete reinforcement materials
- Synthesis and Characterization of Heterocyclic Compounds
- Membrane Separation and Gas Transport
- Synthesis of Organic Compounds
- 14-3-3 protein interactions
- Face and Expression Recognition
- Calpain Protease Function and Regulation
- Optical Wireless Communication Technologies
- Machine Learning in Healthcare
Chinese Academy of Surveying and Mapping
2025
Wuhan University
2011-2025
Rhode Island Hospital
2024-2025
Brown University
2023-2025
Xiyuan Hospital
2025
Peking University
2025
Wuhan Institute of Virology
2024
State Key Laboratory of Virology
2024
East China Jiaotong University
2024
Ministry of Education of the People's Republic of China
2024
Flexible sensors, friendly interfaces, and intelligent recognition are important in the research of novel human-computer interaction development smart devices. However, major challenges still encountered designing user-centered devices with natural, convenient, efficient interfaces. Inspired by characteristics textile-based flexible electronic this article, we report a braided cord low-cost, automated fabrication to realize imperceptible, designable, scalable user The is miniaturized form,...
Abstract Endowing flexible and adaptable fiber devices with light-emitting capabilities has the potential to revolutionize current design philosophy of intelligent, wearable interactive devices. However, significant challenges remain in developing when it comes achieving uniform customizable light effects while utilizing lightweight hardware. Here, we introduce a mass-produced, wearable, photochromic that provides multicolored control. We designed independent waveguides inside maintain total...
Flexible strain sensors have attracted much attention due to their good flexibility, high sensitivity, superior repeatability, and great potentials for application in physiological signal detection. Carbon materials, including carbon nanotubes, graphene, black, graphite, natural-bioderived materials are often used as active the fabrication of flexible because electrical conductivity flexibility. Among them, nanotubes graphene can be prepared into various forms, such fibers, films, or...
Background Alzheimer's disease (AD) is a complex neurodegenerative marked by increased amyloid-β (Aβ) deposition, tau hyperphosphorylation, impaired energy metabolism, and chronic ischemia-type injury. Cerebral microvascular dysfunction likely contributes to AD pathology, but its precise pathogenic role has been poorly defined. Objective To examine reactivity endothelium-dependent vasodilators small conductance calcium-activated potassium (SK) channel activity in an intracerebral...
Temperate glaciers in the Kangri Karpo region of southeastern Qinghai–Tibet Plateau (QTP) have experienced significant ablation recent decades, increasing risk glacier-related hazards and impacting regional water resources. However, spatial temporal pattern mass loss these remains inadequately quantified. In this study, we used ASTER L1A stereo images to construct a high-resolution elevation time series provide comprehensive spatial–temporal assessment glacier change from 2000 2024. The...
Clinical trials of receptor-biased interleukin-2 (IL-2) variants in cancer therapy show limited efficacy. To investigate, we re-evaluated divergent IL-2 PEGylates (generated via site-specific PEGylation at residues D20 (not-β) and Y45 (not-α)), alone or combination. Results showed the not-α variant (Y45) activates regulatory T cells (Tregs) βγ chain binding, overriding CD8+ impairing Conversely, not-β (D20) is inert but spatially blocks Y45's engagement, suppressing Treg activation. also...
The active edge site, surface defect, and noble-metal nanoparticle have been engineered to improve the electrocatalytic activity of earth-abundant layered MoS2, but there was no single facile process achieve all yet. Here, basal-plane-defected Ag/MoSx lamellae with different Ag contents were deposited by one-step, single-cermet target (ceramic + metal) magnetron sputtering for hydrogen evolution reaction (HER). (10 vol %) showed a current density 10 mA/cm2 at an overpotential 120 mV Tafel...
Herein, we reported a practical and efficient strategy combining photoredox enzyme catalysis for the construction of 3-aminoalkyl chromones from o-hydroxyaryl enaminones N-arylglycine esters. A variety were synthesized with good yields under mild conditions in one pot. This synthetic protocol consists sequential enzymatic hydrolysis decarboxylation esters, oxidation aminoalkyl radicals, Mannich reaction, intramolecular nucleophilic cyclization, which affords convenient pathway preparation...
An electrochemical strategy has been developed for the one-step synthesis of 1,4-phenylenediamine.
1,4-Dicarbonyl compounds are versatile scaffolds for the heterocycle synthesis, including Paal–Knorr reaction. Herein, a feasible electrosynthesis method to access 1,4-dicarbonyl has been developed from simple alkynes and 1,3-dicarbonyl compounds. When undivided cell is combined with constant current mode, aryl containing numerous medicinal motifs esters or ketones react smoothly. External oxidant catalyst-free conditions conform requirements of green synthesis.
Most methods used to synthesize and prepare NiAl intermetallics their alloys have the disadvantages of complexity high cost. In this paper, alloy was prepared by a Combustion Synthesis Hot Pressing (CSHP) technique under rapid solidification. The grain size is significantly refined 60–80 μm, which reduces stress concentration during deformation improves fracture strength hardness. Moreover, large internal greater amount dislocations in as-cast microstructure are produced formation pressure...
Background: Sodium–glucose cotransporter-2 (SGLT2) inhibitors are known to be cardioprotective independent of glucose control, but the mechanisms these benefits unclear. We previously demonstrated improved cardiac function and decreased fibrosis in a swine model chronic myocardial ischemia. The goal this study is use high-sensitivity proteomic analyses characterize specific molecular pathways affected by SGLT-2 inhibitor canagliflozin (CAN) therapy Methods: Chronic ischemia was induced...
Amino acids are an important class of biomass raw materials, which widely used as starting materials to synthetize bioactive molecules, drugs and functional also useful organic catalysts or metal ligands for asymmetric synthesis.Visible-light-induced transformation has attracted enormous interest due its intrinsic characteristics sustainability green chemistry.The use visible-light promote decarboxylative coupling α-amino construct various nitrogen-containing compounds been considered...
This paper investigated the mechanical and electroconductivity properties of graphite tailings concrete, in which are replaced as sand. The results showed that concentration has an important influence on mechanical, electroconductivity, material concrete. Finally, a new model for calculating relationship between compressive strength electrical resistivity based grey correlation method was obtained providing theoretical basis building green intelligent materials.
Organophotocatalytic cascade cross-dehydrogenative-coupling/cyclization reaction of o-hydroxyarylenaminones with α-amino acid derivatives for the construction α-chromone substituted was developed. Various N-arylglycine esters, amides and dipeptides underwent cyclization well to afford corresponding 3-aminoalkyl chromones in good excellent yields. This approach consists visible-light-promoted oxidation derivatives, Mannich reaction, intramolecular nucleophilic under acidic conditions,...
Organic phosphine-promoted organic synthesis reactions have developed rapidly in recent years.Triphenylphosphine and their derivatives are the most important class of phosphine compounds, which can not only serve as ligands reactions, but also deoxygenative promoters a large number reactions.In years, visible-light-induced coupling aroused considerable attention.This type reaction uses phosphines to promote single electron transfer form P-O intermediates with oxygen-containing molecules...
A green synthesis method for the oxidation of sodium dialkyldithiocarbamate to corresponding thiuram disulfides was developed in presence CO2 as neutralizing agent, H2O2 oxidant, and water solvent. The could provide much greener reaction conditions, convert a relatively high-quality product without H2SO4 consumption, obtain high yields purity products. effects flow rate, temperature, concentration, dropping speed, excess degree hydrogen peroxide, well concentration dimethyldithiocarbamate,...
Purpose This paper aims to study the working principle of capacitive pressure sensor and explore distribution acting on surface capacitor. Herein, a kind high sensitivity was prepared by overlaying carbon fibers (CFs) surfaces thermoplastic elastomer (TPE), TPE with elasticity is dielectric for CFs excellent electrical conductivity were designed as conductor. Design/methodology/approach Due mechanical properties CFs, it conductor layer TPE/CFs via laminating columnar TPE. Then, ‘#' type...