Mariasevera Di Comite

ORCID: 0000-0003-2450-4425
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Temporomandibular Joint Disorders
  • Bone fractures and treatments
  • Fish Biology and Ecology Studies
  • Fish Ecology and Management Studies
  • Dental Radiography and Imaging
  • Salivary Gland Disorders and Functions
  • Adipose Tissue and Metabolism
  • Aquaculture Nutrition and Growth
  • Bone Tissue Engineering Materials
  • Inflammatory mediators and NSAID effects
  • Bone Metabolism and Diseases
  • Dental Implant Techniques and Outcomes
  • Bone health and osteoporosis research
  • Mitochondrial Function and Pathology
  • Oral Health Pathology and Treatment
  • Oral and Maxillofacial Pathology
  • dental development and anomalies
  • Mesenchymal stem cell research
  • Osteoarthritis Treatment and Mechanisms
  • Endodontics and Root Canal Treatments
  • Dental materials and restorations
  • Oropharyngeal Anatomy and Pathologies
  • Ichthyology and Marine Biology
  • Adipokines, Inflammation, and Metabolic Diseases
  • Systemic Lupus Erythematosus Research

University of Bari Aldo Moro
2015-2024

Significance Although exercise is a well known and potent stimulus for new bone formation, weightlessness or muscle loss characteristically cause loss, it has remained unclear how talks to bone, despite their close proximity. Here, we show that molecule irisin derived from skeletal in response profound effects enhancing mass improving the geometry strength specifically of cortical key function which resist bending torsion. Trabecular reservoir bodily calcium, remarkably spared. Irisin may...

10.1073/pnas.1516622112 article EN Proceedings of the National Academy of Sciences 2015-09-15

The rapid recovery of smell and taste functions in COVID-19 patients could be attributed to a decrease interleukin-6 levels rather than central nervous system ischemic injury or viral damage neuronal cells. To correlate with olfactory gustatory dysfunctions investigate the role IL-6 onset these disorders, this observational study investigated 67 disorders both, who did not require intensive care admission, admitted at COVID Hospital Policlinico Bari from March May 2020. Interleukin-6 was...

10.1021/acschemneuro.0c00447 article EN other-oa ACS Chemical Neuroscience 2020-08-04

In this study we evaluated the performance of Skelite, a resorbable bioceramic based on silicon stabilized tricalcium phosphate (Si-TCP), in promoting repair large-sized, experimentally induced defect weight-bearing long bone sheep model. Eighteen 2-year-old ewes were used study. Animals sacrificed at 3, 6, and 12 months. One animal entered very prolonged followup was 2 years after surgery. Bone formation scaffold resorption by sequential x-ray studies, CT scans, histology, immunohistology,...

10.1089/ten.2006.12.1261 article EN Tissue Engineering 2006-05-01

Background: Stem cells are defined as clonogenic capable of self-renewal and multi-lineage differentiation.A population these has been identified in human Dental Follicle (DF).Dental Cells (DFSCs) were found pediatric unerupted wisdom teeth have shown to differentiate, under particular conditions, into various cell types the mesenchymal tissues.Aim: The aim this study was investigate if isolated from DF show stem features, differentiate toward osteoblastic phenotype express markers.Methods:...

10.7150/ijms.4583 article EN cc-by-nc International Journal of Medical Sciences 2012-01-01

AIMS:Psoriasis is a chronic, remitting and relapsing inflammatory disorder, involving the skin, nails, scalp mucous membranes, that impairs patients' quality of life to varying degrees.Psoriatic arthritis chronic seronegative, arthritis, usually preceded by psoriasis.Temporomandibular disorders generic term referred clinical conditions jaw muscles temporomandibular joint.The aim this study was assess symptoms signs in psoriasis patients with without psoriatic arthritis. METHODS:The group...

10.7150/ijms.11288 article EN cc-by-nc International Journal of Medical Sciences 2015-01-01

Aims: Temporomandibular disorders (TMD) represent a heterogeneous group of inflammatory or degenerative diseases the stomatognatic system, with algic and/or dysfunctional clinical features involving temporomandibular joint (TMJ) and related masticatory muscles.Rheumatoid Arthritis (RA) is an autoimmune polyarthritis characterized by chronic inflammation synovial joints oral implications such as hyposalivation, difficulty in swallowing phoning, feeling burning mouth, increased thirst, loss...

10.7150/ijms.28361 article EN cc-by-nc International Journal of Medical Sciences 2019-01-01

Aims: Systemic Lupus Erythematosus (SLE) is a connective tissue disease characterized by wide range of pleomorphic pictures, including mucocutaneous, renal, musculoskeletal and neurological symptoms.It involves oral tissues, with hyposalivation, tooth decay, gingivitis, angular cheilitis, ulcers glossitis.Temporomandibular disorders represent heterogeneous group inflammatory or degenerative diseases the stomatognatic system, algic and/or dysfunctional clinical features involving...

10.7150/ijms.38914 article EN cc-by-nc International Journal of Medical Sciences 2020-01-01

AIMS:Sjӧgren Syndrome is a disorder involving oral tissues, with xerostomia, dysgeusia, dysphagia, tooth decay, gingivitis, angular cheilitis and glossitis.Temporomandibular disorders are generic term referred to clinical conditions the jaw muscles temporomandibular joint.The aim of this study was investigate prevalence manifestations (TMD) in Sjӧgren (SS) patients compared healthy people. METHODS:The group included 72 SS (2 men, 70 women) diagnosed according American-European Consensus...

10.7150/ijms.23044 article EN cc-by-nc International Journal of Medical Sciences 2018-01-01

To investigate how the interfacial shear strength of dentin-post interface with and without defects changes for different combinations irrigant/sealer.In forty human decoronated instrumented teeth, fibreglass posts were inserted. The obtained root segments randomly assigned to four groups according irrigant adopted cement used seal canal. processed metyl-methacrylate embedding. Serial sections submitted histomorphometric analyses in order observe any defect adhesion at measure defects'...

10.7150/ijms.4998 article EN cc-by-nc International Journal of Medical Sciences 2012-01-01

Bone loss induced by ovariectomy is due to the direct activity on bone cells and mesenchymal dysregulated of marrow cells, including immune stromal but underlying mechanisms are not completely known. Here, we demonstrate that induces T-cell co-stimulatory cytokine LIGHT, which stimulates both osteoblastogenesis osteoclastogenesis modulating osteoclastogenic expression, TNF, osteoprotegerin, receptor activator nuclear factor-κB ligand (RANKL). Predictably, LIGHT-deficient (Tnfsf14-/- ) mice...

10.1002/path.5385 article EN The Journal of Pathology 2020-01-28

The objective of this study was to assess frequency and extension the defects affecting dentin-post interface after using different combinations irrigants sealers. experimental work conducted on single-rooted teeth extracted for orthodontic reasons. specimens were divided into groups, according irrigant endodontic cement utilized, endodontically instrumented. After fiberglass posts cementation, cross sections obtained at apical, middle coronal level root submitted quantitative analyses....

10.3390/ma8063268 article EN Materials 2015-06-04

Dens invaginatus (D.I.) is a developmental anomaly caused by the infolding of surface tooth crown before calcification has occurred. Its aetiology controversial and remains unclear. It occurs in all dentitions with prevalence that ranges from 0.25% to 7.74% mostly seen maxillary permanent incisors, particularly lateral incisors. Posterior teeth are infrequently involved.The purpose this study was investigate morpho‐structure second upper molar dens compared control tooth. Ground decalcified...

10.3109/01913120903506595 article EN Ultrastructural Pathology 2010-01-01

ABSTRACT Multiple cytokines produced by immune cells induce remodeling and aid in maintaining bone homeostasis through differentiation of bone-forming osteoblasts bone-resorbing osteoclasts. Here, we investigate controlled the tumor necrosis factor (TNF) superfamily cytokine LIGHT. LIGHT-deficient mice (Tnfsf14-/-) exhibit spine deformity reduced femoral cancellous mass associated with an increase osteoclast number a slight decrease compared WT mice. The effect LIGHT can be direct or...

10.1002/jbmr.3345 article EN Journal of Bone and Mineral Research 2017-11-27

To compare the effectiveness of two different routes antibiotic administration in preventing septic complications patients undergoing third molar extraction.Twenty-four healthy requiring bilateral surgical removal impacted mandibular molars were successfully enrolled for this study. Depth impaction, angulation, and relationship lower with branch had to be overlapping on both sides. A split-mouth design was chosen, so each patient underwent first second surgeries, having extraction a route...

10.7471/ct.2014.1665 article EN PubMed 2014-01-01

Hard tissue regeneration represents a challenge for the Regenerative Medicine and Mesenchymal stem cells (MSCs) could be successful therapeutic strategy. T-LysYal® (T-Lys), new derivative of Hyaluronic Acid (HA) possessing superior stability, has already been proved efficient in repairing corneal epithelial damaged by dry conditions vitro. We investigated regenerative potential T-Lys hard tissues bone cartilage. have previously demonstrated that isolated from tooth germ, Dental Bud Stem...

10.3389/fendo.2020.00285 article EN cc-by Frontiers in Endocrinology 2020-05-05

The aim of this study was to evaluate the levels vitamin D (25OHD) and other bone biomarkers in patients with third molar impaction (TMI). Thirty males 30 females unilateral or bilateral impacted mandibular molar, 15 as a control group (CG) were recruited. Rx-OPT used dental position Pederson index measure difficulty intervention. Bone measured through blood venous sample TMI CG. Mann-Whitney test, Pearson's correlation coefficient, linear regression model compare different parameters two...

10.3390/nu13061938 article EN Nutrients 2021-06-04

To investigate the correlation between dorsal tongue porphyrin autofluorescence, revealed using VELscope, and Candida saprophytism.Consecutive patients underwent an autofluorescence examination by VELscope device to establish presence or absence of fluorescence. A swab was collected for cultural test. Sensitivity, specificity, accuracy, negative predictive value positive were calculated considering oral as gold standard. The degree agreement two tests Cohen's K coefficient.One hundred...

10.1371/journal.pone.0223072 article EN cc-by PLoS ONE 2019-09-26

The oral conditions of an individual are the result different factors, including subject's genotype, hygiene habits, type diet, and lifestyle, such as smoking. Nutrition in first years life can affect dental health for a long time. To prevent mouth diseases, it is also important to eliminate unfavorable eating behaviour amplify protective ones. Eating especially pediatric age, easily modifiable controllable factor, addition influencing cavity, plays fundamental role systemic health. Indeed,...

10.1155/2021/9992451 article EN cc-by BioMed Research International 2021-10-29

The study investigated the prevalence of temporomandibular disorders in 100 competitive athletes contact sports, equally grouped by practiced game: Soccer (SoG), Rugby (RG), American Football (AFG), Boxing (BoG), Basketball (BaG), compared to a randomly control group 20 non-athletes (CG). Symptoms and signs were examined according standardized Diagnostic Criteria for Temporomandibular Disorders through questionnaire clinical evaluation. Arthralgia showed significant differences between RG CG...

10.3390/dj10100180 article EN cc-by Dentistry Journal 2022-09-27

Aim: Inflammatory idiopathic myopathies (IIMs) are inflammatory processes affecting skeletal musculature and extramuscular organs.Temporomandibular disorders (TMD) involve jaw muscles temporomandibular joint.The aim of this observational study was to investigate the prevalence main TMD symptoms signs as well oral implications in IIM patients. Methods:The group included 54 patients (42 women 12 men), 22 whom affected by dermatomyositis (DM), 29 polymyositis (PM) 3 inclusion body myositis...

10.7150/ijms.45226 article EN cc-by-nc International Journal of Medical Sciences 2021-01-01

As for any industrial sector, the aquaculture industry needs to minimize production costs increase business profit and competitiveness. A source of loss finfish hatcheries is one related skeletal anomalies resulting fish deformities. Farming conditions can induce morphofunctional changes in physiology behaviour (Almeida et al., 2008; Corriero 2011; Kihslinger & Nevitt, 2006; Zupa 2013, 2017). Skeletal may cause negative effects on growth, welfare health (Koumoundouros 2001; Sfakianakis...

10.1111/jfd.13622 article EN Journal of Fish Diseases 2022-04-09
Coming Soon ...