A5022320894- Oceanographic and Atmospheric Processes
- Tropical and Extratropical Cyclones Research
- Coastal wetland ecosystem dynamics
- Coastal and Marine Dynamics
- Ocean Waves and Remote Sensing
- Infectious Diseases and Tuberculosis
- Marine and coastal ecosystems
- Tuberculosis Research and Epidemiology
- Orthopedic Infections and Treatments
- Spinal Fractures and Fixation Techniques
- Mycobacterium research and diagnosis
- Geological formations and processes
- Gut microbiota and health
- Cancer-related molecular mechanisms research
- Musculoskeletal pain and rehabilitation
- Ginseng Biological Effects and Applications
- Methane Hydrates and Related Phenomena
- Climate variability and models
- Marine Biology and Ecology Research
- Bone Metabolism and Diseases
- Diagnosis and treatment of tuberculosis
- Cancer Research and Treatments
- Tryptophan and brain disorders
- Marine and coastal plant biology
- Nanoplatforms for cancer theranostics
First Affiliated Hospital of Guangzhou Medical University
2025
Guangzhou Medical University
2025
Nanjing University of Chinese Medicine
2020-2025
Chengdu University of Traditional Chinese Medicine
2025
University of Science and Technology of China
2025
Xiamen University
2014-2024
University of Arkansas for Medical Sciences
2024
Lingnan Normal University
2024
University Hospitals Geauga Medical Center
2024
Heilongjiang University of Chinese Medicine
2023
Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases (IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut microbiota represents new treatment strategy IBD patients. Rhein is one of the main components rhubarb and exhibits poor oral bioavailability but still exerts anti-inflammatory effects some diseases. Therefore, we investigated effect rhein on studied its possible mechanisms. Methods: The chronic mouse model was...
Dietary factors are fundamental in tumorigenesis throughout our lifetime. A spicy diet has been ambiguous on the development of cancers, especially study colon cancer metastasis. Here, we utilized a mouse metastasis model to test potential role capsaicin influencing Long-term continuous administration (300 mg/kg) mice promotes formation liver pre-metastatic niche facilitate cells. Bacteria translocation is clearly observed. Capsaicin increases intestinal barrier permeability and disrupts gut...
Abstract Kidney renal clear cell carcinoma (KIRC) is the most general subtype of carcinoma, which composes about 1/20 adult malignancies. The anomaly long noncoding RNAs (lncRNAs) expression proved to mediate cancer progression various types. function and mediation mechanism MSC‐AS1 has rarely been detected in KIRC before. This study started with on function. In this study, was dramatically upregulated correlated dismal prognosis patients. Knockdown would suppress proliferative migratory...
Abstract Residual currents induced by asymmetric tidal mixing were examined for weakly stratified, narrow estuaries using analytical and numerical models. The model is an extension of the work R. K. McCarthy, with addition variations vertical eddy viscosity in longitudinal momentum equation. distribution residual flows driven determined current amplitude asymmetries between flood ebb. In a long channel, magnitude flow maximum at estuary mouth decreases upstream following amplitude. Larger...
Residual currents induced by asymmetric tidal mixing (ATM) were examined using a series of idealized numerical experiments for weakly stratified, partially mixed, and highly stratified narrow estuaries that neglected lateral variations bathymetry the effects Earth's rotation.The Eulerian residual decomposed into four components, i.e., river-induced, density-driven, nonlinearities-induced, ATM-induced flows such longitudinal distribution strength each component can be depicted evaluated.In...
Tropical Storm Lee (2011) caused a record flood in the Susquehanna River which discharged about 6.7 million tons of suspended sediments into Bay, an amount equal to input 6 average years. The flood‐carried sediment produced large plume that covered one half Chesapeake Bay with maximum concentration exceeding 2500 mg L −1 . Three stages were identified development plume, corresponding three dominant forcing mechanisms, i.e., river flow, estuarine circulation, and settling. Most deposited...
Abstract Mangrove wetlands support numerous ecosystem services including nutrient cycling and carbon sequestration storage (blue carbon). sediments may serve as a nitrogen source or sink to the hydrosphere atmosphere at both regional global scales. However, major mechanisms controlling connection between mangrove adjacent tidal creek (nitrogen in outfluxing) remain unclear. A multidisciplinary study based on intensive investigation, incorporating detailed sediment profiling, multi‐isotopes...
Abstract Both observational and reanalysis sea surface temperature data reveal that upwelling occurs frequently off the northeastern coast of Hainan Island (downstream change in topography Tongluo Cape), which cannot be attributed to along‐shelf wind alone. To identify dynamics upwelling, we conduct a numerical experiment using an idealized is simplified from actual eastern coasts Island. The result indicates downstream associated with onshore cross‐isobath transport. Analysis vertically...
Abstract Objectives Abdominal aortic aneurysm (AAA) is an inflammation-driven disease in which neutrophil infiltration critical to its progression. This study aims explore the molecular mechanisms behind AAA and identify key regulatory genes. Methods We utilized weighted gene co-expression network analysis (WGCNA) differential expression compare healthy abdominal tissues. Functional enrichment a protein–protein interaction (PPI) were constructed understand functions. Machine learning...
The surgical treatment of bone tumors generally causes defects, whilst postoperative infection and tumor recurrence may also occur. Currently, it is still a huge challenge to design multi-functional biomaterials that both eradicate residual cells bacteria promoting osteogenesis. Herein, hafnium oxide with an oxygen vacancy (HfO2-x) was synthesized via deoxidation reaction shown exhibit excellent photothermal performance. Moreover, composite based on polyetheretherketone (PEEK) containing...
Abstract The influence of nonlinear lateral advection on estuarine exchange flow is examined with a scaling analysis and eight groups idealized numerical experiments. Nonlinear related to the linkage between circulation shear along-estuary flow. relative contribution overall dynamics microtidal estuary found be function width depth, vertical mixing. Lateral dynamically important in narrow deep estuaries, particularly under relatively weak importance earth’s rotation can evaluated terms...
Abstract The dynamics of lateral circulation in the Passaic River estuary is examined this modeling study. pattern varies significantly over a tidal cycle as result temporal variation stratification induced by straining. During highly stratified ebb tides, exhibits vertical two-cell structure. Strong suppresses mixing deep channel, whereas shoal above halocline remains relatively well mixed. As result, upper layer, asymmetry produces denser water on and fresher thalweg. This density gradient...
Abstract Background DNA microarrays can detect tuberculosis and its multi-drug resistant form in M. isolates sputum specimens with high sensitivity specificity. However, no performance data currently exists for use spinal specimens. This study was aimed to assess the of CapitalBio™ microarray detection isoniazid (INH) rifampicin (RMP) resistance compared BACT/MGIT 960 system. Methods From March 2009 December 2011, 153 consecutive patients from Southwest Hospital, Chongqing clinically...
Abstract The dynamics associated with lateral circulation in a tidally driven estuarine channel is analyzed on the basis of streamwise vorticity. Without rotational effects, differential advection and diffusive boundary mixing produce two counterrotating vortices (in cross-channel section) whose strength sense may change during tidal cycle. vorticity equation determined by balance between baroclinic forcing turbulent diffusion, which explains flood–ebb asymmetry circulation. Analysis...
The role of asymmetric tidal mixing (ATM) in subtidal estuarine dynamics is investigated using a series generic numerical experiments that simulate narrow estuaries under different stratification and external forcing conditions. focus on quantifying the characteristics ATM‐induced flow its contributions to salt transport. induced by ATM has two‐layer vertical structure periodically stratified estuaries, similar density‐driven flow. It three‐layer central regime weakly reverse highly...