A5050824917- Analytical Chemistry and Chromatography
- Saffron Plant Research Studies
- Computational Drug Discovery Methods
- Spectroscopy and Chemometric Analyses
- Flavonoids in Medical Research
- Advanced Chemical Sensor Technologies
- Analytical Methods in Pharmaceuticals
- Dye analysis and toxicity
- Chromatography in Natural Products
- Phytochemistry and Biological Activities
- Metabolomics and Mass Spectrometry Studies
- Neurological Disease Mechanisms and Treatments
- Analytical chemistry methods development
- Natural product bioactivities and synthesis
- Curcumin's Biomedical Applications
- Retinal Development and Disorders
- Phytochemicals and Antioxidant Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Graphene research and applications
- Fermentation and Sensory Analysis
- Graphene and Nanomaterials Applications
- Molecular spectroscopy and chirality
- Covalent Organic Framework Applications
- Microfluidic and Capillary Electrophoresis Applications
- Electrospun Nanofibers in Biomedical Applications
University of L'Aquila
2008-2025
University of Bari Aldo Moro
2011
University of Perugia
2000
Mario Negri Institute for Pharmacological Research
1994
Novel polystyrene-based molecularly imprinted polymer nanofibers were synthesized through the electrospinning technique. The polymers prepared using a non-covalent approach and atrazine as template. For comparison, nonimprinted also synthesized. morphology of was characterized scanning electron microscopy. adsorption pesticides, atrazine, desisopropyl, atraton, carboxin, linuron, chlorpyrifos studied under equilibrium (batch) conditions. To describe capability polymers, Langmuir Freundlich...
Crocus sativus L. belongs to the Iridaceae family and it is commonly known as saffron. The different cultures together with geoclimatic characteristics of territory determine a chemical composition that characterizes final product. This why complete knowledge this product fundamental, from which more than 150 compounds have been extracted from, but only about one third them identified. saffron has studied in relation its efficacy coping neurodegenerative retinal diseases. Accordingly,...
In this work, pristine graphene oxide and its thermally reduced derivatives, rGO, were tested for the removal of triazines (atraton, prometryn, atrazine) from water. The reduction process was optimized by means design experiments (DOE) coupled with response surface methodology (RSM), relying on adsorption efficiency material. optimal conditions calculated at a temperature 110 °C maintained 24 h; mildest simplest protocol chosen, as it allows in-air heat treatment common laboratory oven. rGO...
Headspace Solid-Phase Microextraction coupled to Gas-Chromatography with Mass Spectrometry detection (HS-SPME/GC-MS) has been widely used analyze the composition of wine aroma. This technique was here applied investigate volatile profile Trebbiano d'Abruzzo and Pecorino white wines produced in Abruzzo (Italy). Optimization SPME conditions conducted by Design Experiments combined Response Surface Methodology. We investigated influence kind sorbent, PDMS, CW/DVB, or PDMS/CAR/DVB, effect fiber...
The mutations observed in the various forms of retinitis pigmentosa (RP) affect genes coding for rod-specific proteins and direct progression different dystrophy toward total blindness. present investigation aims to explore protective effects Saffron Repron, a mouse model RP. was administered orally pregnant females weaned pups 120 days. At time points (P30, P60, P90, P120), visual function, retinal cone lifespan, morphology, gene expression, protein level were analyzed. results indicate...
In this paper, a multilayer artificial neural network is used to model simultaneously the effect of solute structure and eluent concentration profile on retention s-triazines in reversed-phase high-performance liquid chromatography under linear gradient elution. The data 24 triazines, including common herbicides their metabolites, are collected 13 different elution modes, covering following experimental domain: starting acetonitrile volume fraction ranging between 40 60% slope 0 1%...
Multi-walled carbon nanotubes (MWCNTs), because of their small size and large available surface area, are potentially efficient sorbents for the extraction water solutes. Dispersion MWCNTs in aqueous medium is suitable to adsorb organic contaminants from sample volumes, but, recovery suspended sorbent successive re-use represents a critical step, which makes this method inapplicable large-scale water-treatment technologies. To overcome problem, we proposed here grown on silicon supports...
Ultra-high performance liquid chromatography (UHPLC) coupled with diode array detection (DAD) was applied to improve separation and of mono- bis-glucosyl esters crocetin (crocins), the main red-colored constituents saffron (Crocus sativus L.), other polar components. Response surface methodology (RSM) used optimise chromatographic resolution on Kinetex C18 (Phenomenex) column taking into account combined effect temperature, eluent flow rate slope a linear concentration gradient. A...
Recently, we have proposed an approach to multi-column RP-HPLC retention modelling under isocratic conditions based on a combination of five molecular descriptors, the volume fraction organic modifier in mobile phase and column descriptor, simultaneously considered as dependent variables artificial neural network (ANN) regression. The particular, was identified with observed average solutes used calibration extrapolated pure water phase. ANN-based model seen accurately describe pool...