A5042099265- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Veterinary Oncology Research
- Neurological disorders and treatments
- MRI in cancer diagnosis
- Veterinary Orthopedics and Neurology
- Prostate Cancer Treatment and Research
- Advanced Neuroimaging Techniques and Applications
- Glaucoma and retinal disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Corneal surgery and disorders
- Cerebrospinal fluid and hydrocephalus
- Infrared Thermography in Medicine
- Hearing, Cochlea, Tinnitus, Genetics
- Orthopedic Surgery and Rehabilitation
- Corneal Surgery and Treatments
- Hemophilia Treatment and Research
- Animal Vocal Communication and Behavior
- Blood properties and coagulation
- Rabies epidemiology and control
- Drug Transport and Resistance Mechanisms
- Cerebrovascular and Carotid Artery Diseases
- Extracellular vesicles in disease
University of Veterinary Medicine Hannover, Foundation
2012-2024
Kantonsschule Olten
2019
Ludwig-Maximilians-Universität München
2018
University Hospital Heidelberg
2007-2013
Heidelberg University
2000-2013
University Medical Centre Mannheim
2005-2013
Central Institute of Mental Health
2013
University of Veterinary Medicine Vienna
2013
Heidelberg University
2010-2012
Fundación Juan March
2011
Magnetic resonance imaging (MRI) is a powerful tool to assess brain lesions, but currently available contrast agents are limited in the assessment of cellular and functional alterations. By use novel MRI agent gadofluorine M (Gf) we report on transient widespread changes blood-brain barrier (BBB) properties as consequence focal photothrombotic lesions rats. After i.v. application, Gf led bright also entire ipsilateral cortex T1-weighted MRI. In contrast, enhancement after application...
Purpose: The aim of the present study was to analyze and compare in vivo morphology healthy cornea six different laboratory animals.
Appendicular osteosarcoma (OSA) is a highly metastatic tumour in dogs. The aim of the study was to compare thoracic radiographs with computed tomography (CT) staging canine appendicular OSA. In all, 39 patients histologically diagnosed OSA were reviewed retrospective study. All dogs underwent radiographic examination as well CT cavity. Pulmonary nodules detected radiographically two cases (5%), whereas imaging showed that pulmonary evident 11 (28%, P = 0.024). There an improved detection...
Reliable visualization of the subthalamic nucleus (STN) is indispensable for accurate placement electrodes in deep brain stimulation (DBS) surgery patients with Parkinson disease (PD). The aim study was to evaluate different promising new MRI methods at 3.0 T preoperative STN using a standard installation protocol.Magnetic resonance imaging studies (T2-FLAIR, T1-MPRAGE, T2*-FLASH2D, T2-SPACE, and susceptibility-weighted sequences) obtained 9 healthy volunteers 1 patient PD were acquired. Two...
The aim of our study was to visualize developing vessel occlusion in focal cerebral ischemia vivo. Cortical photothrombosis (PT) induced rats, which addition received superparamagnetic iron oxide (SPIO) particles intravenously. When SPIO were applied simultaneously during illumination the brain for induction PT, animals showed a markedly hypointense cortical lesion on T2-weighted (T2-w) magnetic-resonance images (MRI). At 3 h after this area surrounded by small hyperintense rim. 48 PT rim...
Acquired chemoresistance during chemotherapy, often accompanied by cross- and multi-resistance, limits therapeutic outcomes leads to recurrence. In order create in vitro model systems understand acquired doxorubicin-resistance, we generated doxorubicin-resistant sublines of canine prostate adenocarcinoma urothelial cell carcinoma lines. Chemoresistance doxorubicin, cross-resistance carboplatin, the reversibility resistance specific MDR1-inhibitor tariquidar were quantified metabolic assays....
Characterization of lacunar infarction (LI) by use multimodal MRI including diffusion- and perfusion-weighted imaging (DWI, PWI) is difficult because the small lesion size. Only a few studies evaluated PWI in LI results are inconsistent.In 16 patients who underwent initial within 6 hours after symptom onset follow-up 1 week demographics, clinical presentation, findings were analyzed with special emphasis on DWI findings. Time to peak maps classified as showing normal perfusion pattern or...
Collagen cross-linking using the photosensitizer riboflavin combined with ultraviolet A light was developed to stiffen cornea by increasing its mechanical and biochemical stability. Investigation of post-treatment events, such as wound healing, is important evaluate possible risks optimize treatment protocols. This in vivo confocal laser-scanning microscopy study rabbits conducted provide a quantitative qualitative analysis corneal repair over 16 weeks following collagen cross-linking.Six...
Abstract Background Functional magnetic resonance imaging (fMRI) is a technique able to localize neural activity in the brain by detecting associated changes blood flow. It an essential tool for studying human functional neuroanatomy including auditory system. There are only few studies, however, using fMRI study canine functions. In current ten anesthetized dogs were scanned during stimulation. Two sequences, each combination with suitable stimulation paradigm, used subject. Sequence 1...