Daniel J. Leonard

ORCID: 0000-0003-2503-0890
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About
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Space Exploration and Technology
  • Spaceflight effects on biology
  • Aerodynamics and Acoustics in Jet Flows
  • Chemical Synthesis and Analysis
  • Acoustic Wave Phenomena Research
  • Cavitation Phenomena in Pumps
  • Spacecraft Design and Technology
  • Asymmetric Synthesis and Catalysis
  • Nuclear Materials and Properties
  • Spacecraft and Cryogenic Technologies
  • Hydraulic and Pneumatic Systems
  • Speech and Audio Processing
  • Nuclear reactor physics and engineering
  • Supramolecular Self-Assembly in Materials
  • Chemical synthesis and alkaloids
  • Cyclone Separators and Fluid Dynamics
  • Fluorine in Organic Chemistry
  • Advanced Synthetic Organic Chemistry
  • Fluid Dynamics and Vibration Analysis
  • Gas Dynamics and Kinetic Theory
  • Innovations in Medical Education
  • Graphene and Nanomaterials Applications
  • Islanding Detection in Power Systems

Novametrics (United Kingdom)
2024

University of Bristol
2018-2021

University of Florida
2021

TerraMetrics (United States)
2020

Bellevue Hospital Center
2020

Terra
2019

Pennsylvania State University
2008-2015

General Electric (United States)
2015

University of Manchester
2013-2014

Tractebel Engineering (Belgium)
2012

Dianionic enolates formed from N′-aryl urea derivatives of amino acids undergo intramolecular C-arylation by attack the enolate anion on ring, leading to a hydantoin derivative quaternary acid. In situ IR studies allow identification four intermediates reaction pathway.

10.1039/c3cc46193a article EN Chemical Communications 2013-01-01

Imidazolidinone derivatives of a range aromatic α-amino acids, on treatment with phosgene and potassium iodide, undergo mild Bischler–Napieralski-style cyclocarbonylation reaction that generates tricyclic lactam by insertion C═O group between amino acid nitrogen the ortho position aryl substituent. Regio- diastereoselective functionalization library substituted dihydroisoquinolinones their congeners in enantioenriched form.

10.1021/acs.orglett.8b03551 article EN Organic Letters 2018-12-05

The International Space Station (ISS) overboard leakage of cabin atmosphere is continually tracked to identify new or aggravated leaks and provide information for planning nitrogen supply the ISS. difficult trend with various constituents being added removed. Changes partial pressure nominal means trending leakage. This paper summarizes method presents findings from trending.

10.2514/6.2011-5149 article EN 41st International Conference on Environmental Systems 2011-07-17

Both <italic>R</italic> and <italic>S</italic> enantiomers of Fmoc-protected amino acids bearing α-aryl substituents may be made on gram scale. Solid-phase synthesis leads to helical peptides unperturbed by the presence these additional groups.

10.1039/d1sc01378e article EN cc-by Chemical Science 2021-01-01

N-acyl imidazolidinones, which are key intermediates in the stereoselective synthesis of amino acids by "self-regeneration stereochemistry" methods, classically made only moderately diastereoselective methods. We now report that cyclization pivaldimino-amides with phosgene presence pyridine may be fully for trans-N-chloroformylimidazolidinones, and we detail conformational features products. show despite electrophilic carbamoyl chloride function products remarkable stability deprotonated to...

10.1021/acs.joc.9b00727 article EN The Journal of Organic Chemistry 2019-05-15

TerraPower participated in a cooperative project among industry, national laboratory, and university to perform verification validation of computational fluid dynamics (CFD) methods for predicting the flow heat transfer within fuel assemblies with hexagonally packed wire-wrapped pins. This consisted both experimental numerical components used surrogate fluids electrically heated pins substitute liquid metal nuclear fuel. performed CFD simulations experiments using industrial-level...

10.1080/00295450.2020.1727263 article EN Nuclear Technology 2020-03-30

The International Space Station (ISS) Airlock Crewlock can be depressurized via various methods. ISS is divided into two major sections, the Equipment Lock and Crewlock. Lock, as name indicates, contains equipment to support EVA activities including Extravehicular Maneuvering/Mobility Unit (EMU) maintenance refurbishment. also basic life in order denitrogenzation protocols while isolated from rest of ISS. section that allow for Activity (EVA) crewmembers exit performance EVAs. As opposed...

10.4271/2004-01-2594 article EN SAE technical papers on CD-ROM/SAE technical paper series 2004-07-19

Steady-periodic multiphase Computational Fluid Dynamics (CFD) simulations were conducted to capture cavitation breakdown in a Francis hydroturbine due large-scale vaporous structures. A reduced-scale model and full-scale prototype investigated display differences vapor content machine performance caused by lack of Reynolds Froude similarity. The scale efficiencies compared favorably (within 3%) the experimental tests. CFD displayed distinct qualitative quantitative as σ was reduced....

10.1115/ajkfluids2015-5123 article EN 2015-07-26

<title>Abstract</title> The risk of inducing hypoglycaemia (low blood glucose) constitutes the main challenge associated with insulin therapy for diabetes. Insulin doses must be adjusted to ensure glucose values within normal range, but matching fluctuating levels is difficult since even a slightly higher dose than needed can lead hypoglycaemic incidence which anything from uncomfortable life-threatening. It has thus been long-standing goal engineer glucose-sensitive that auto-adjust its...

10.21203/rs.3.rs-2882397/v1 preprint EN cc-by Research Square (Research Square) 2023-05-09

The International Space Station (ISS) loses cabin atmosphere mass at some rate. Due to oxygen partial pressures fluctuations from metabolic usage, the total pressure is not a good data source for tracking loss. Using nitrogen determine on-orbit loss ISS, due no addition or losses. There are several important reasons know daily average air of ISS including logistics planning and oxygen. was estimated January 14 April 9 2003. includes structural leakages, Vozdukh losses, Carbon Dioxide Removal...

10.4271/2004-01-2597 article EN SAE technical papers on CD-ROM/SAE technical paper series 2004-07-19

l -Tyrosine provides a precursor for practical synthesis of the unstable primary metabolite -arogenate and some stabilised arogenate analogues.

10.1039/d1sc03554a article EN cc-by Chemical Science 2021-01-01

10.4271/2005-01-2896 article EN SAE technical papers on CD-ROM/SAE technical paper series 2005-07-11

10.4271/2005-01-2894 article EN SAE technical papers on CD-ROM/SAE technical paper series 2005-07-11

10.4271/2005-01-2897 article EN SAE technical papers on CD-ROM/SAE technical paper series 2005-07-11

This new 6-page publication of the UF/IFAS Horticultural Sciences Department aims to inform Florida growers and craft brewing distillery industry about current knowledge potential yield challenges barley cultivation in north Florida. Written by Charles E. Barrett, Lincoln Zotarelli, Sylvia M. Willis, Jay Capasso, Ethan T. Carter, De Broughton, Kevin R. Athearn, Andrew MacIntosh, Alicia N. Halbritter, Matthew Smith, A. Korus, Daniel J. Leonard.https://edis.ifas.ufl.edu/hs1420

10.32473/edis-hs1420-2021 article EN EDIS 2021-09-14

This paper examines the control of combustion turbine generators to maintain stability when transitioning from interconnected operation islanded operation. Specifically, describes an Isochronous operating scheme regulate system frequency along with load sharing for maintaining during a cogeneration power plant at petroleum processing facility in Abqaiq, Saudi Arabia. All aspects solution are discussed. Simulations dynamic performance number islanding scenarios described. The discusses...

10.1109/cicps.2015.7974047 article EN 2015-11-01

Abstract The treatment of 1‐cyanoethyl ureas (I) with sBuLi leads to iminohydantoins (II) as a result an aryl migration and cyclization.

10.1002/chin.201406150 article EN ChemInform 2014-01-23
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