A5014444354- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Risks and Factors
- Tumors and Oncological Cases
- Cancer Treatment and Pharmacology
- Enzyme function and inhibition
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Chemotherapy-related skin toxicity
- Thyroid Cancer Diagnosis and Treatment
- Cutaneous Melanoma Detection and Management
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Head and Neck Cancer Studies
- Medical Imaging and Pathology Studies
- Viral-associated cancers and disorders
- Growth Hormone and Insulin-like Growth Factors
- Chemotherapy-induced cardiotoxicity and mitigation
- Vascular Tumors and Angiosarcomas
- Blood Pressure and Hypertension Studies
- Bone health and treatments
- Melanoma and MAPK Pathways
- Cancer, Hypoxia, and Metabolism
- Nonmelanoma Skin Cancer Studies
- Childhood Cancer Survivors' Quality of Life
Karadeniz Technical University
2011-2021
Ankara University
2002
To prospectively determine whether the diffusion-weighted magnetic resonance imaging is useful to distinguish between malignant and benign mediastinal lymph nodes.Thirty-five patients (14 women, 21 men; mean age 52 years) with 91 nodes in mediastinum detected by computed tomography underwent 1.5 Tesla (T) MR before mediastinoscopy (n = 29) mediastinotomy 6). Diffusion-weighted images were acquired a b factor of 50, 400 s/mm(2) using single-shot echo-planar sequence.Of 35 patients, 18 had...
The influence of hypothyroidism on haemostasis is controversial; both hypocoagulable and hypercoagulable states have been reported. Hypothyroidism has associated with atherosclerosis; a state in addition might represent risk factor for thromboembolic disease. aim the present study was to investigate markers endogenous coagulation vascular endothelial cell function evaluate relationship between serum lipid profile, thyroid hormones haemostatic parameters hypothyroid patients. We investigated...
The relation between cancer and coagulation is the subject of investigation since a tumor thrombosis has been determined. Antithrombin III an important thrombin inhibitor, increased thrombin-antithrombin (TAT) complex levels activate coagulation. Activated activatable fibrinolysis inhibitor (TAFI) inhibits conversion plasminogen to plasmin. In addition, it directly inactivates Defective increases risk thrombosis. this study, we evaluated homeostatic parameters, TAFI, TAT in patients with...
Reactive oxygen species (ROS) are found in the development stages of carcinogenesis.Fifty two patients with gastric cancer and 35 controls were enrolled this trial.IMA, MDA, Total Oxidant Status (TOS), Antioxidant (TAS) Oxidative Stress Index (OSI) evaluated.There was a significant increase IMA MDA levels patient group (0.405±0.111, 0.271±0.066;p= 0.0001 0.207±0.251,0.077±0.103;p= 0.004 respectively).TOS also higher but it not statistically different.TAS lower there difference OSI...
Cytokines play important roles in the pathogenesis of lymphomas. The aim this study was to determine relations between serum levels interleukin-2 (IL-2), IL-6, and IL-10 parameters International Prognostic Index (IPI). Serum IL-2, were measured using a sensitive enzyme-linked immunosorbent assay pretreatment frozen sera from 43 patients with non-Hodgkin's lymphoma. we included divided into two groups, one high risk other low according IPI regard their ages, stages, performance status,...
Purposes: This study was intended to determine the diagnostic significance of signal peptide-CUB-EGF domain-containing protein 1 (SCUBE 1) levels in gastric cancer. Methods: retrospective conducted with patients SC
Studies have investigated expression status of galectin-3 (Gal-3), but very little is known about the importance circulating Gal-3 in patients with breast cancer (BC). The purpose study was to investigate clinical significance and potential diagnostic value plasma levels BC.Fifty-two BC 35 age-matched healthy controls were enrolled. Levels controls. determined using ELISA method.Serum significantly higher than (P = 0.002). did not differ according patients' statuses lymph node involvement,...
Breast cancer (BC) is the most common among women and a major cause of death. Signal Peptide-Cub-Epidermal growth factor domain-containing protein-1 (SCUBE1) secreted under hypoxia inflammatory conditions from platelet alpha granules. Its biological function uncertain, although it may be procoagulant substance in patients. SCUBE1 useful for identifying thrombotic diseases, including cancers acute coronary syndromes. D-dimer reflects relationship between coagulation activation fibrinolysis;...
Mucosal melanoma (MM) is a rare type of cancer that differs significantly from cutaneous melanoma. In this study, we aimed to evaluate clinical and demographical characteristics, prognoses factors influencing survival, treatment alternatives, features different subtypes the patients. The patients were followed up with treated in centers due their diagnoses MM. We retrospectively analyzed data 107 who diagnosed MM 14 institutions Turkey. mean age was 64.5 years. Of patients, 47 % female 53...
INTRODUCTION: Breast-cancer is a common-cause of death in women.(1)We investigated the effects before/after-NACT on hemoglobin-albumin-lymphocyte-platelet (HALP) scores and changes therein clinical/pathological-responses.MATERIALS AND METHODS: One-hundred-twenty-seven breast-cancer-patients receiving-NACT between December 2009 -January 2019 were retrospectively.RESULTS: The mean -age was 50.3±12.3(min 27 -max 79), 125 patients (98.4 %) women.Fiftyfour (42.5 premenopausal 71 (55.9...
<i>Objective:</i> To report a case of Hodgkin’s disease presenting with immune hemolytic anemia. <i>Clinical Presentation and Intervention:</i> A 47-year-old man was admitted to hospital because weight loss, fever, inguinal lymph node adenopathy. Biopsy the revealed mixed-cellularity disease. Three days after starting combined chemotherapy, patient showed evidence autoimmune anemia, which responded well prednisolone. <i>Conclusion:</i> This shows that...
Cetuximab is an epidermal growth factor receptor inhibitor. It frequently used in the treatment of solid tumors. However, it has a high potential to cause acne-like rash. Demodex mites, which are known increase number immunosuppressive circumstances, closely related acneiform lesions.The aim this study evaluate presence demodex mites rash that appears under Cetuximab.We reviewed medical records patients who applied our clinic with cetuximab induced papulopustular rashes between November 2014...
Since multiple myeloma responds poorly to conventional chemotherapy or radiotherapy, new therapeutic approaches are needed. This study investigated the effects of dexamethasone, all-trans retinoic acid (ATRA), active metabolite vitamin D(3) [1,25(OH)(2)D(3)] and interferon-alpha on FO mouse cells (non-immunoglobulin-secreting cell line) in single drug combination groups vitro.Apoptosis ratio change counts 4 (dexamethasone, ATRA, interferon-alpha) 6 (dexamethasone + D(3,) dexamethasone...
To report a rare case of carcinoma erysipelatoides on the laryngeal skin caused by stomach adenocarcinoma.A 48-year-old male, who had undergone gastrectomy 18 months prior to admission for stage IIIA gastric adenocarcinoma, presented with reddish induration cervical skin, lymphadenopathy in both supraclavicular areas and widespread subcutaneous nodules. Abdominal computerized tomography chest radiography did not reveal any organ metastasis or peritoneal carcinomatosis. A biopsy revealed...