A5002683944- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Cancer Treatment and Pharmacology
- Lymphoma Diagnosis and Treatment
- Cancer Risks and Factors
- Cancer Genomics and Diagnostics
- Breast Lesions and Carcinomas
- Chemotherapy-related skin toxicity
- Cancer and Skin Lesions
- Nutrition, Genetics, and Disease
- Breast Cancer Treatment Studies
- Lung Cancer Treatments and Mutations
- Helicobacter pylori-related gastroenterology studies
- BRCA gene mutations in cancer
- Renal cell carcinoma treatment
- Neutropenia and Cancer Infections
- Erythropoietin and Anemia Treatment
- Blood groups and transfusion
- Viral-associated cancers and disorders
- Cancer-related Molecular Pathways
- Blood disorders and treatments
- Chronic Lymphocytic Leukemia Research
- Global Cancer Incidence and Screening
Karadeniz Technical University
2015-2024
Trakya University
2020
Ibero American University
2019
Dicle University
2007
Gaziantep University
2007
Erciyes University
2007
Başkent University
2004
The only phase 3 study on the effectiveness of CDK 4-6 inhibitors in first-line treatment premenopausal patients with hormone receptor (HR) positive, HER2 negative metastatic breast cancer is MONALEESA-7 study, and data palbociclib limited. Data are also limited regarding whose dose was reduced due to neutropenia, most common side effect inhibitors. In our we aimed evaluate ribociclib reduction neutropenia progression-free survival. Our a multicenter, retrospective factors affecting survival...
The relation between cancer and coagulation is the subject of investigation since a tumor thrombosis has been determined. Antithrombin III an important thrombin inhibitor, increased thrombin-antithrombin (TAT) complex levels activate coagulation. Activated activatable fibrinolysis inhibitor (TAFI) inhibits conversion plasminogen to plasmin. In addition, it directly inactivates Defective increases risk thrombosis. this study, we evaluated homeostatic parameters, TAFI, TAT in patients with...
Reactive oxygen species (ROS) are found in the development stages of carcinogenesis.Fifty two patients with gastric cancer and 35 controls were enrolled this trial.IMA, MDA, Total Oxidant Status (TOS), Antioxidant (TAS) Oxidative Stress Index (OSI) evaluated.There was a significant increase IMA MDA levels patient group (0.405±0.111, 0.271±0.066;p= 0.0001 0.207±0.251,0.077±0.103;p= 0.004 respectively).TOS also higher but it not statistically different.TAS lower there difference OSI...
Cytokines play important roles in the pathogenesis of lymphomas. The aim this study was to determine relations between serum levels interleukin-2 (IL-2), IL-6, and IL-10 parameters International Prognostic Index (IPI). Serum IL-2, were measured using a sensitive enzyme-linked immunosorbent assay pretreatment frozen sera from 43 patients with non-Hodgkin's lymphoma. we included divided into two groups, one high risk other low according IPI regard their ages, stages, performance status,...
Amikacin is a commonly used antibacterial drug that can cause significant nephrotoxic effects in both humans and experimental animals. It has been reported one mechanism of the toxic aminoglycoside antibiotics are result oxidative reactions. The aim this study to examine N-acetylcysteine, thiol-containing antioxidant, on renal function (serum creatinine) morphology (renal tubular damage) mice subjected amikacin-induced nephrotoxicity. A total 32 were equally divided into four groups injected...
Studies have investigated expression status of galectin-3 (Gal-3), but very little is known about the importance circulating Gal-3 in patients with breast cancer (BC). The purpose study was to investigate clinical significance and potential diagnostic value plasma levels BC.Fifty-two BC 35 age-matched healthy controls were enrolled. Levels controls. determined using ELISA method.Serum significantly higher than (P = 0.002). did not differ according patients' statuses lymph node involvement,...
Breast cancer (BC) is the most common among women and a major cause of death. Signal Peptide-Cub-Epidermal growth factor domain-containing protein-1 (SCUBE1) secreted under hypoxia inflammatory conditions from platelet alpha granules. Its biological function uncertain, although it may be procoagulant substance in patients. SCUBE1 useful for identifying thrombotic diseases, including cancers acute coronary syndromes. D-dimer reflects relationship between coagulation activation fibrinolysis;...
Combination of gemcitabine and nab-paclitaxel has superior clinical efficacy than alone. Nevertheless, health-related quality life. (QoL) associated with this combination therapy when administered at first-line in advanced pancreatic adenocarcinoma is unknown.A total 125 patients were randomized to (1000 mg/m2 + nab-paclitaxel) single-agent mg/m2) arms take treatment weekly for 7 8 weeks, following 3 4 until progression or severe toxicity. Primary endpoints three-months definitive...
Many possible causes of resistance to human recombinant erythropoietin (rh-EPO) have been reported in patients with renal failure. This case presents an unusual cause erythropoietin-resistant anemia a patient chronic A 61-year-old male who was on hemodialysis program due diabetic nephropathy for seven months developed resistant anemia. No iron deficiency revealed by laboratory data, no megaloblastic were found biochemical investigation, and inflammatory states including infection or...
An association between the ABO blood group and risk of certain malignancies, including pancreatic gastric cancer, has been reported previously. However, it is unclear whether this valid for gastrointestinal stromal tumors (GIST). In study, groups Rh factor were investigated in a series GIST cases.In 162 patients with GIST, examined compared control 3,022,883 healthy volunteer donors Turkish Red Crescent 2004 2011. The relationship tumor size, mitotic activity, age also evaluated.Overall,...
<i>Objective:</i> To report a case of Hodgkin’s disease presenting with immune hemolytic anemia. <i>Clinical Presentation and Intervention:</i> A 47-year-old man was admitted to hospital because weight loss, fever, inguinal lymph node adenopathy. Biopsy the revealed mixed-cellularity disease. Three days after starting combined chemotherapy, patient showed evidence autoimmune anemia, which responded well prednisolone. <i>Conclusion:</i> This shows that...
To evaluate the effect of desmopressin (DDAVP) on hemostatic parameters during dialysis and in interval between sessions.Fifteen patients dialyzed twice weekly at least for 1 year 15 healthy volunteers serving as a control group were enrolled study. Bleeding time, platelet count, prothrombin activated partial thromboplastin tissue plasminogen activator (tPA), inhibitor (PAI-1), euglobulin clot lysis protein C, S, fibrinogen, D-dimer, factor V, VII, VIII, IX, X von Willebrand (VWF) values...