Rachel M. Gilbert

ORCID: 0000-0003-2523-9483
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About
Contact & Profiles
Research Areas
  • Congenital Diaphragmatic Hernia Studies
  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Neonatal Respiratory Health Research
  • COVID-19 and healthcare impacts
  • Infection Control and Ventilation
  • Cellular Mechanics and Interactions
  • Radical Photochemical Reactions
  • Gas Sensing Nanomaterials and Sensors
  • Analytical Chemistry and Sensors
  • Vanadium and Halogenation Chemistry
  • Infection Control in Healthcare
  • Climate Change and Health Impacts
  • Various Chemistry Research Topics
  • Neuropeptides and Animal Physiology
  • Molecular Spectroscopy and Structure
  • Virus-based gene therapy research
  • Atomic and Molecular Physics
  • Neurobiology and Insect Physiology Research
  • Oxidative Organic Chemistry Reactions
  • Skin and Cellular Biology Research
  • Neuroblastoma Research and Treatments
  • Receptor Mechanisms and Signaling
  • Pleural and Pulmonary Diseases
  • CO2 Reduction Techniques and Catalysts

University of Delaware
2016-2023

Cornell University
2016-2023

Santa Clara University
2010

Université de Montréal
1975

Repairing tears in the nuclear envelope The segregates genomic DNA from cytoplasm and regulates protein trafficking between cytosol nucleus. Maintaining integrity during interphase is considered crucial. However, Raab et al. Denais show that migrating immune cancer cells experience frequent transitory ruptures when they move through tight spaces (see Perspective by Burke). reseals rapidly interphase, assisted components of ESCRT III membrane-remodeling machinery. Science , this issue pp. 359...

10.1126/science.aad7297 article EN Science 2016-03-25

The Hei photoelectron and vacuum ultraviolet spectra up to about 20 eV of CF3Be, CF2Br2, CF2BrCl have been measured. In both spectra, we find bands at energies lower than in the corresponding chlorine derivatives. Otherwise, can be interpreted along similar lines. lowest ionization potentials frequency are due transitions from bromine lone pair orbitals.

10.1063/1.430495 article EN The Journal of Chemical Physics 1975-01-15

ABSTRACT Congenital diaphragmatic hernia (CDH) is a developmental disorder associated with diaphragm defects and lung hypoplasia. The etiology of CDH complex its clinical presentation variable. We investigated the role pulmonary mesothelium in dysregulated growth noted Wt1 knockout mouse model CDH. Loss WT1 leads to intrafetal effusions, altered growth, branching prior normal closure diaphragm. found significant differences key genes; however, when null lungs were cultured ex vivo,...

10.1242/dev.199460 article EN Development 2021-05-15

Lamins A/C are nuclear intermediate filament proteins that involved in diverse cellular mechanical and biochemical functions. Here, we report recognition of by a commonly used antibody (JOL-2) binds the Lamin Ig-fold other antibodies targeting similar epitopes is highly dependent on cell density, even though A/Clevels do not change. We propose effect caused partial unfolding or masking C'E and/or EF loops response to spreading. Surprisingly, JOL-2 labeling was insensitive disruption...

10.1080/19491034.2023.2180206 article EN cc-by Nucleus 2023-02-21

ABSTRACT As the current COVID-19 pandemic illustrates, not all hospitals and other facilities are equipped with enough personal protective equipment to meet demand in a crisis. Healthcare workers around world utilize N95 masks protect themselves their patients, yet during this global they forced re-wear what is intended be single-use masks. This poses significant risk these healthcare along populations trying protect. Ultraviolet germicidal irradiation (UVGI) has been validated previously as...

10.1101/2020.04.19.20070870 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-04-24

Broadband (λ > 320 nm) irradiation of (Bu4N)2Pd2Br6 in chloroform causes the conversion to . During conversion, is decomposed photocatalytically at a rate that accelerates then decelerates as coordinated bromines are replaced by chlorines. The primary bromine-containing product CCl3Br. observations consistent with mechanism which and intermediate complexes undergo homolytic photodissociation bromine or chlorine atom, terminates trichloromethyl radical abstracts hydrogen from chloroform, respectively.

10.1080/00958970903582696 article EN Journal of Coordination Chemistry 2010-02-12

Abstract Lamins A/C are nuclear intermediate filament proteins that involved in diverse cellular mechanical and biochemical functions. Here, we report recognition of by a commonly used antibody (JOL-2) binds the Lamin Ig-fold other antibodies targeting similar epitopes is highly dependent on cell density, even though protein levels do not change with density. The density-dependent labeling was distinct from previously reported differential apico-basal labeling, which independent Comparison...

10.1101/2022.11.22.517482 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2022-11-22
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