A5103083534- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
- Nanoparticle-Based Drug Delivery
- Random lasers and scattering media
- Inorganic Fluorides and Related Compounds
- Nanoplatforms for cancer theranostics
- Perovskite Materials and Applications
- Nonlinear Optical Materials Research
- Radiation Detection and Scintillator Technologies
- Photorefractive and Nonlinear Optics
- Advanced Fiber Laser Technologies
- Advanced Photocatalysis Techniques
- Advanced Nanomaterials in Catalysis
- Glass properties and applications
- Orbital Angular Momentum in Optics
- Analytical chemistry methods development
- Cancer, Hypoxia, and Metabolism
- Terahertz technology and applications
- Advanced biosensing and bioanalysis techniques
- Layered Double Hydroxides Synthesis and Applications
- Neural Networks and Reservoir Computing
- Catalytic Processes in Materials Science
- Nonlinear Photonic Systems
- Carbon and Quantum Dots Applications
- Nanomaterials for catalytic reactions
Ministry of Water Resources of the People's Republic of China
2025
China Institute of Water Resources and Hydropower Research
2025
Huazhong University of Science and Technology
2004-2024
Eye & ENT Hospital of Fudan University
2020-2024
Foshan University
2015-2024
Union Hospital
2024
Sichuan University
2023-2024
China Medical University
2024
Foshan Ceramics Research Institute (China)
2024
Chinese Academy of Sciences
2011-2023
We present a facile surfactant-free solvothermal method for the fabrication of nearly monodispersed Fe3O4 submicroparticles with tunable particle sizes ranging from 130 to 420 nm by varying concentration single iron source FeCl3·6H2O in initial solutions. The morphology and crystal structure as-prepared have been well characterized using SEM/TEM/HRTEM, XRD, FT-IR, Raman spectroscopy, XPS methods. It is found that particles single-crystal nature strong ferromagnetic property magnetization...
Nearly monodispersed magnetic Fe(3)O(4)@DFUR-LDH submicro particles containing the anticancer agent DFUR were prepared via a coprecipitation-calcination-reconstruction strategy of LDH materials over surface Fe(3)O(4) particles, and present well-defined core-shell structure, strong magnetization obvious magnetically controlled drug delivery release properties.
Autophagy is an intracellular degradation process for recycling macromolecules and organelles. It plays important roles in plant development response to nutritional demand, stress, senescence. Organisms from yeast plants contain many autophagy-associated genes (ATG). In this study, we found that a total of 33 ATG homologues exist the rice [Oryza sativa L. (Os)] genome, which were classified into 13 subfamilies. Six them are alternatively spliced genes. Evolutional analysis showed expansion...
Platinum-based chemotherapy is used for non-small cell lung cancer (NSCLC). However, it has side effects and minimum efficacy against metastasis. In this study, platinum-curcumin complexes were loaded into pH redox dual-responsive nanoparticles (denoted as Pt-CUR@PSPPN) to facilitate intracellular release synergistic anti-cancer effects. Pt-CUR@PSPPN was prepared by a nano-precipitation method had diameter of ∼100 nm. The showed increased both in vivo vitro. addition, blocked PI3K/AKT signal...
Artificial aquaporins are synthetic molecules that mimic the structure and function of natural (AQPs) in cell membranes. The development artificial would provide an alternative strategy for treatment AQP-related diseases. In this report, aquaporin has been constructed from amino-terminated tubular molecule, which operates a unimolecular mechanism. channel can work membranes with high water permeability selectivity rivaling those AQPs. Importantly, restore wound healing cells contain function-lost
Lung cancer in never-smokers (LCINS) presents clinicopathological and molecular features distinct from that smokers. Tumor microenvironment (TME) plays important roles progression therapeutic response. To decipher the difference TME between never-smoker smoker lung cancers, we conduct single-cell RNA sequencing on 165,753 cells 22 treatment-naive adenocarcinoma (LUAD) patients. We find dysfunction of alveolar induced by cigarette smoking contributes more to aggressiveness LUADs, while...
Hypoxia, acidosis and high level of glutathione (GSH) are characteristic abnormalities the tumor microenvironment (TME), which promote progression, metastasis, resistance to therapies. Previous attempts improve therapeutic efficacy were limited modifying individual TME elements. In this study, we proposed a comprehensive modulation strategy that modifies multiple elements in order enhance cisplatin anticancer efficacy. To do so, prepared biocompatible lipid-coated CaO2/cisplatin...
Novel hierarchical core@shell structured salicylate (SA) intercalated ZnAl-LDH (layered double hydroxides) magnetic nanovehicles were obtained via a special double-drop coprecipitation strategy assembling organo-ZnAl-LDH nanocrystals onto the surface of Fe3O4 submicrospheres (∼480 nm) from cheap aspirin and Zn- Al-nitrates in alkaline solutions. The Fe3O4@SA-LDH-r exhibit varied morphologies with hexagonal LDH ab-face horizontal, vertical, vertical/slant/horizontal to surfaces upon proper...
Abstract Perinatal hypoxic‐ischemic encephalopathy (HIE) is a leading cause of neonatal death and neurological disability. Oxidative stress neuroinflammation are typical pathogenic factors HIE. Licochalcone A (LCA) exerts various biological properties, including anti‐inflammatory antioxidant activities. However, no data have been reported to elucidate the role LCA in development In present study, primary cultured rat cortical neurons were exposed oxygen‐glucose deprivation/reoxygenation...
Three novel polydiacetylenes (PDAs) are synthesized through the self-assembly followed by topochemical polymerization via controllable electrophoretic deposition. All samples could undergo a multi-step thermochromic process, turning purple and red successively over wide range from room temperature to above 250 °C. Resulting PDAs studied UV–vis, IR, Raman spectroscopies, chromoisomerism naked eye visualization; their stabilities thermogravimetric method, emission behavior fluorescence...
A novel aptamer biosensor for fast tetracyclines determination was established and illustrated in this paper. The as a specific affinity molecule immobilized on the surface of glassy carbon (GC) electrodes. It can specifically bind quickly milk other samples without sample treatment. Subsequently, electrochemical signals are produced measured accurately. linear relationship between currents concentration is 0.1–100ng ml−1. sensitivity limit device 1ng detection time 5 min.
A novel 3D oxide nanosheet array catalyst was fabricated using a graphene template induced strategy for highly efficient NO<sub>x</sub> capture and catalytic soot combustion.
Nanoparticle formulations have proven effective for cisplatin delivery. However, the development of a versatile nanoplatform cisplatin-based combination cancer therapies still remains great challenge. Methods: In this study, we developed one-pot synthesis method microporous organosilica shell-coated using reverse microemulsion method, and explored its application in co-delivering acriflavine (ACF) inhibiting hypoxia-inducible factor-1 (HIF-1). Results: The resulting nanoparticles were...
Drug transportation is impeded by various barriers in the hypoxic solid tumor, resulting compromised anticancer efficacy. Herein, a lipid monostearin (MS)-coated CaO2/MnO2 nanocarrier was designed to optimize doxorubicin (DOX) comprehensively for chemotherapy enhancement. The MS shell of nanoparticles could be destroyed selectively highly-expressed lipase within cancer cells, exposing water-sensitive cores release DOX and produce O2. After cell death, core-exposed further liberated continue...
Development of highly thermally stable broadband near-infrared (NIR) luminescence materials is crucial for advancing the prolonged application smart NIR light sources. In this study, a zero-thermal-quenching and reversible temperature-dependent NIR-emitting Cs2NaAl3F12:Cr3+ phosphor demonstrated, benefiting from its polyhedron-cluster-building rigid structure. The excellent thermal stability rooted in [Al6Na4F45] cluster building unit, which provides structure with weak electron–phonon...
Abstract To strengthen the antitumor efficacy and avoid toxicity to normal cells of cisplatin triptolide, herein, an acid glutathione (GSH) dual‐controlled nanoplatform for enhanced cancer treatment through synergy both “1+1” apoptosis ferroptosis is designed. Remarkably, ZIF8 in response tumor microenvironment enhances drug targeting protects drugs from premature degradation. Meanwhile, Pt IV center can be easily reduced because large amount GSH, thus liberating triptolide as coordinated...