Davide Milani

ORCID: 0000-0003-2561-6795
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About
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Research Areas
  • Nanoparticle-Based Drug Delivery
  • Characterization and Applications of Magnetic Nanoparticles
  • Iron oxide chemistry and applications

Technical University of Munich
2022-2023

Iron oxide nanoparticles (IONs) are of great interest in nanomedicine for imaging, drug delivery, or hyperthermia treatment. Although many research groups have focused on the synthesis and application IONs nanomedicine, little is known about influence surface properties particles' behavior human body. This study analyzes impact coatings (dextran, polyvinyl alcohol, polylactide-co-glycolide) nanoparticles' cytocompatibility, agglomeration, degradation, resulting oxidative stress induced by...

10.1016/j.heliyon.2023.e16487 article EN cc-by Heliyon 2023-05-25

Carboxymethyl-dextran (CMD)-coated iron oxide nanoparticles (IONs) are of great interest in nanomedicine, especially for applications drug delivery. To develop a magnetically controlled delivery system, many factors must be considered, including the composition, surface properties, size and agglomeration, magnetization, cytocompatibility, activity. This study reveals how CMD coating thickness can influence these particle properties. ION@CMD synthesized by co-precipitation. A higher quantity...

10.3390/ijms232314743 article EN International Journal of Molecular Sciences 2022-11-25

Coated iron oxide nanoparticles (IONs) are promising candidates for various applications in nanomedicine, including imaging, magnetic hyperthermia, and drug delivery. The application of IONs nanomedicine is influenced by factors such as biocompatibility, surface properties, agglomeration, degradation behavior, thrombogenicity. Therefore, it essential to investigate the effects coating material thickness on behavior performance human body. In this study, with a carboxymethyl dextran (CMD) two...

10.1016/j.colsurfb.2023.113428 article EN cc-by Colloids and Surfaces B Biointerfaces 2023-06-24
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