A5064846323- X-ray Diffraction in Crystallography
- Microbial Natural Products and Biosynthesis
- Crystallization and Solubility Studies
- Marine Sponges and Natural Products
- Fungal Biology and Applications
- Organic Chemistry Cycloaddition Reactions
- Chemical Synthesis and Reactions
- Biological and pharmacological studies of plants
- Synthesis and Catalytic Reactions
- Crystallography and molecular interactions
- Cancer-related molecular mechanisms research
- Synthesis and Characterization of Heterocyclic Compounds
- Inorganic and Organometallic Chemistry
- Chemistry and Chemical Engineering
- Bioactive Compounds and Antitumor Agents
- Synthetic Organic Chemistry Methods
- Synthesis and biological activity
- RNA Research and Splicing
- Sulfur-Based Synthesis Techniques
- Porphyrin and Phthalocyanine Chemistry
- Chemical synthesis and alkaloids
Union Hospital
2025
Jilin University
2025
Sun Yat-sen University
2017-2019
Saitama University
1990
ABSTRACT Gastric cancer (GC) represents a major global health concern, with over 1 million new cases diagnosed annually worldwide. Emerging studies have highlighted the significant correlation between long noncoding RNAs (lncRNAs) and progression of GC. The objective current study is to investigate roles mechanism lncRNA homeobox A10 antisense RNA (HOXA10‐AS) in modulating malignant properties GC cells. RT‐qPCR was employed detect HOXA10‐AS expression cells or human normal gastric epithelium...
Six new polyketides, including one coumarin (1), two isocoumarins (2 and 3), dihydroradicinin (4), benzofuranone derivatives (7 8), together with seven known analogues (5-6 9-13) were isolated from the culture of mangrove endophytic fungus Epicoccum nigrum SCNU-F0002. The structures elucidated on interpretation spectroscopic data. absolute configuration Compounds 2 3 determined by comparison their ECD spectra data analogue dihydroisocoumarins described in literature. 4 was single-crystal...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFirst isolable dithiiranes: 3-(1,1,3,3-tetramethyl-4-oxo-4-phenylbutyl)-3-phenyldithiirane 1-oxidesAkihiko Ishii, Toru Akazawa, Meng Xin Ding, Takanari Honjo, Juzo Nakayama, Masamatsu Hoshino, and Motoo ShiroCite this: J. Am. Chem. Soc. 1993, 115, 11, 4914–4915Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://doi.org/10.1021/ja00064a072RIGHTS & PERMISSIONSArticle...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSulfurization of nonenolizable diketonesAkihiko Ishii, Juzo Nakayama, Meng Xin Ding, Noboru Kotaka, and Masamatsu HoshinoCite this: J. Org. Chem. 1990, 55, 8, 2421–2427Publication Date (Print):April 1, 1990Publication History Published online1 May 2002Published inissue 1 April 1990https://pubs.acs.org/doi/10.1021/jo00295a034https://doi.org/10.1021/jo00295a034research-articleACS PublicationsRequest reuse permissionsArticle...
Seven new compounds: diaporchromanones A–D (<bold>1–4</bold>), (−)-phomopsichin A (<bold>5a</bold>), (+)-phomopsichin B (<bold>6a</bold>), and (±)-diaporchromone (<bold>7</bold>), along with the known (<bold>5b</bold>) (<bold>6b</bold>) were isolated from an endophytic fungus <italic>Diaporthe phaseolorum</italic> SKS019.
This investigation reports the synthesis of benzoimidazole-2-one based macrocyclic arenes 1 and 2 by one-pot condensation strategy via nucleophilic substitution reactions. X-ray crystallographic study demonstrates that cooperative hydrogen halogen...