A5023364107- Alcohol Consumption and Health Effects
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Substance Abuse Treatment and Outcomes
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cannabis and Cannabinoid Research
- Hepatitis C virus research
- Opioid Use Disorder Treatment
- Schizophrenia research and treatment
- Treatment of Major Depression
- Alcoholism and Thiamine Deficiency
- Renal Transplantation Outcomes and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Forensic Toxicology and Drug Analysis
- Neurological Complications and Syndromes
- Mental Health Treatment and Access
- Pharmacological Effects and Toxicity Studies
- Healthcare professionals’ stress and burnout
- Organ and Tissue Transplantation Research
- Prenatal Substance Exposure Effects
- LGBTQ Health, Identity, and Policy
- Psychiatric care and mental health services
- Hormonal and reproductive studies
- Healthcare Decision-Making and Restraints
University of Pennsylvania
2011-2024
Hospital of the University of Pennsylvania
2007-2024
University of Pennsylvania Health System
2001-2021
Pennsylvania Hospital
2021
Long Island Jewish Medical Center
2010
Georgetown University
2010
Evanston Hospital
2010
New York Hospital Queens
2010
Cambridge Health Alliance
2010
Columbia University
2010
This article assesses the reliability and validity of Cocaine Selective Severity Assessment (CSSA), a measure cocaine abstinence signs symptoms. Interrater scale internal consistency were high. Initial CSSA scores significantly higher in cocaine-dependent subjects than alcohol-dependent subjects. highly correlated with recent use severity measures from Addiction Index (ASI) including interviewer rating composite score drug section. Among subjects, initial for those who failed to achieve or...
Medical Writings: Book Notes19 October 1999Principles of Addiction MedicineMargaret R. Rukstalis, MD and Robert Weinrieb, MDMargaret MDUniversity Pennsylvania Research Center, Philadelphia, Pennsylvania. (Rukstalis, Weinrieb) Weinrieb)Author, Article, Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-8-199910190-00034 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Second edition. Graham AW, Schultz...
Alcohol is the second most common cause of cirrhosis necessitating liver transplantation in United States, yet rates posttransplant drinking approach 50% and no controlled clinical trials alcoholism treatment exist this population. Eligible patients were randomly assigned to receive Motivational Enhancement Therapy (MET), or referral local sources ("treatment as usual" [TAU]). Addictive behavior, mood states, general health compared. Candor concerning alcohol use was encouraged by keeping...
The purpose of donor evaluation for adult-to-adult living liver transplantation (LDLT) is to discover medical conditions that could increase the postoperative risk complications and determine whether can yield a suitable graft recipient. We report outcomes LDLT candidates evaluated in large multicenter study LDLT. records all their respective recipients between 1998 2003 were reviewed as part Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL). recorded along with...
Because results from single-center (mostly kidney) donor studies demonstrate interpersonal relationship and financial strains for some donors, we conducted a liver study involving nine centers within the Adult-to-Adult Living Donor Liver Transplantation Cohort Study 2 (A2ALL-2) consortium. Among other initiatives, A2ALL-2 examined nature of these outcomes following donation. Using validated measures, donors were prospectively surveyed before donation at 3, 6, 12, 24 mo after...
The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a standardized psychosocial evaluation tool used in liver transplantation (LT) evaluation. We assessed the impact of SIPAT score and subdomains on transplant waitlisting decisions post‐LT outcomes including immunosuppression (IS) nonadherence, biopsy‐proven rejection, andmortality/graft failure. conducted single‐center observational cohort study 1430 patients evaluated LT. Patients were divided 2 groups based cutoff...
This study evaluated the ability of cocaine withdrawal symptoms, measured by Cocaine Selective Severity Assessment (CSSA) and initial urine toxicology results, to predict treatment attrition among 128 dependent veterans participating in a 4-week day hospital program. The CSSA was administered screen obtained at intake start (about 1 week later). combination positive high score predicted failure complete treatment. Urine results hospital, but not intake, Among participants without other...
Background. The morbidity and mortality from donation of a right hepatic lobe for living donor liver transplantation (LDLT) is an important issue this procedure. We report the prevalence severe psychiatric postoperative complications Adult-to-Adult Living Donor Liver Transplantation Cohort study (A2ALL), which was established to define risks benefits LDLT donors recipients. Methods. Severe were evaluated in all A2ALL who between 1998 February 2003. Results. Of 392 donors, 16 (4.1%) had one...
Although single-center and cross-sectional studies have suggested a modest impact of liver donation on donor psychological well-being, few assessed these outcomes prospectively among large cohort. We conducted one the largest, prospective, multicenter in living donors within Adult-to-Adult Living Donor Liver Transplantation Cohort Study2 (A2ALL-2) consortium. In total, 271 (91%) 297 eligible were interviewed at least once before 3, 6, 12, 24 mo after using validated measures. found that...
In Brief Background Studies of liver donors' psychosocial outcomes focus on the short term and rely largely quality-of-life measures not specific to donation. We sought examine long-term donation effects 3 domains: perceived physical, emotional, socioeconomic outcomes. Methods Individuals donating 10 years previously at 9 centers were eligible for telephone surveys. Survey responses examined descriptively. Cluster analysis was used identify distinct donor groups based response profiles...
Hepatitis C virus (HCV) is spontaneously cleared in 15% to 45% of individuals during primary infection. To define the role alcohol, race, and HBV or HIV coinfections natural HCV clearance, we examined these parameters 203 HCV-recovered subjects (HCV Ab +/RNA - without prior antiviral therapy) 293 chronically HCV-infected patients +). Subjects were identified from 1,454 antibody-seropositive US veterans tested for RNA between January 2000 July 2002 at Philadelphia Veterans Affairs Medical...
Abstract Objective Serotonin release from platelets is important for regulating hemostasis. Some prior studies suggest an association between use of selective serotonin reuptake inhibitors and gastrointestinal bleeding a possible synergistic effect these medications with non‐steroidal anti‐inflammatory drugs (NSAIDs). This study examined the that inhibit uptake on upper toxicity. Methods 359 case subjects hospitalized bleeding, perforation, or benign gastric outlet obstruction were recruited...
Approximately 85% of patients receiving methadone maintenance therapy (MMT) for opiate dependence in the United States are infected with hepatitis C virus (HCV). MMT is significantly underrepresented most liver transplant programs, but number increasing and few data available to guide treatment. We evaluated our program (27 pretransplant 10 posttransplant cases) medical psychiatric complications anesthesia analgesia requirements. After transplant, were compared a matched control group 19 who...
Abstract Alcohol misuse is the second most common indication for liver transplantation in United States. Our post-transplant alcoholism treatment trial suggested that current interventions might not be transferable to transplantees. We sought identify differences between patients awaiting and alcoholics entering without severe disease. Thirty transplant were compared thirty naltrexone study on medical status, alcohol drug use, craving, motivation treatment, psychiatric symptoms, psychosocial...