A5024250823- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Photoacoustic and Ultrasonic Imaging
- Cardiac Arrest and Resuscitation
- Ultrasound and Hyperthermia Applications
- Thermal Regulation in Medicine
- Atrial Fibrillation Management and Outcomes
- Sports injuries and prevention
- Respiratory Support and Mechanisms
- Thermography and Photoacoustic Techniques
- Sympathectomy and Hyperhidrosis Treatments
- Optical Imaging and Spectroscopy Techniques
- Pain Management and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Climate Change and Health Impacts
- Gun Ownership and Violence Research
- Esophageal and GI Pathology
- Ultrasound Imaging and Elastography
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Diagnosis and Treatment of Venous Diseases
- Advanced MRI Techniques and Applications
- Coronary Interventions and Diagnostics
East Carolina University
2024-2025
Johns Hopkins University
2017-2024
Houston Methodist
2023
Johns Hopkins Medicine
2017-2022
Johns Hopkins Hospital
2019
Beneficência Portuguesa de São Paulo
2008
Abstract Aims Pulsed field ablation (PFA) is a non-thermal ablative approach in which cardiomyocyte death obtained through irreversible electroporation (IRE). Data correlating the biophysical characteristics of IRE and lesion are limited. The aim this study was to assess effect different procedural parameters [voltage, number cycles (NoCs), contact] on vegetal animal model for IRE. Methods results Two hundred four Russet potatoes were used. lesions delivered 3 cm cored potato specimens using...
Cardiac interventional procedures are often performed under fluoroscopic guidance, exposing both the patient and operators to ionizing radiation. To reduce this risk of radiation exposure, we exploring use photoacoustic imaging paired with robotic visual servoing for cardiac catheter visualization surgical guidance. A catheterization procedure was on two in vivo swine after inserting an optical fiber into produce signals from tip fiber-catheter pair. combination employed visualize maintain...
Background: Arrhythmogenic right ventricular cardiomyopathy is an inherited characterized by fibrofatty replacement of myocardium resulting in reentrant tachycardia (VT). Cardiac magnetic resonance imaging (CMR) can noninvasively measure regional abnormalities using tissue-tracking strain as well late gadolinium enhancement (LGE). In this study, we examine arrhythmogenic substrate CMR strain, LGE, and electroanatomic mapping (EAM) patients presenting for VT ablation. Methods Results:...
The Manufacturer and User Facility Device Experience (MAUDE) database houses medical device reports of adverse events involving devices marketed in the United States submitted to U.S. Food Drug Administration (FDA) by mandatory voluntary reporters. MAUDE is frequently used clinical studies report on device-related complications. Data about its efficacy are scarce. We aimed compare (MAUDE group) with invitation-based POTTER-AF study (POTTER-AF 1 regarding data quality, procedural...
Epicardial ablation is becoming an important part of management in patients with ventricular tachycardia (VT). Posterior epicardial access via the Sosa or needle-in-needle (NIN) approach for VT considered to be method choice most electrophysiologists. Anterior as alternative technique has recently been proposed, but there are limited data about its safety, efficacy, and rate immediate complications. In this study, we report our experience anterior between 2009 2016.Between June 2016, 100...
Interventional cardiac procedures often require ionizing radiation to guide catheters the heart. To reduce associated risks of radiation, our group is exploring photoacoustic imaging in conjunc- tion with robotic visual servoing, which requires segmentation catheter tips. However, typical algorithms are susceptible reflection artifacts. address this challenge, signal sources can be identified presence artifacts using a deep neural network, as we previously demonstrated linear array...
Patients with cardiac sarcoidosis (CS) may present arrhythmic events (AE): atrioventricular block (AVB) and/ or ventricular arrhythmias (VA). We sought to: (a) use regional analysis of magnetic resonance imaging (CMR) to describe anatomic and functional phenotypes patients CS AE; (b) Assess the association CMR abnormalities combined endpoint death, heart transplantation (HT) (c) machine learning (ML) predict based on features.we included 76 CMR. analyzed cine images determine longitudinal...
Background Intranasal high flow of dehumidified (dry) air results in evaporative cooling nasal passages. In this randomized clinical trial, we investigated the effect dry gas induced on migraine headaches. Methods single-blind study, acute migraineurs were to either high-flow oxygen, air, humidified oxygen or (control) at 15 L/min for min. All gases delivered 37°C. Severity headache and other associated symptoms (International Classification Headache Disorders, 3rd edition criteria) recorded...
Deep neural networks trained with simulated data are capable of distinguishing sources from reflection artifacts in photoacoustic data. Our group recently introduced this concept and experimental waterbath phantom In novel approach, channel is used as an input to learn the spatial impulse response pressure waves point-like differentiate true artifacts. We hypothesize that possible based on learned differences unique shape-to-depth relationship point sources. The work presented paper builds...
Many cardiac interventional procedures (e.g., radiofrequency ablation) require fluoroscopy to navigate catheters in veins toward the heart. However, this image guidance method lacks depth information and increases risks of radiation exposure for both patients operators. To overcome these challenges, we developed a robotic visual servoing system that maintains visualization segmented photoacoustic signals from catheter tip. This was tested two vivo catheterization with ground truth position...
Targeted temperature management (TTM) is recommended as a standard of care for postcardiac arrest patients. Current TTM methods have significant limitations to be used in an ambulatory setting. We investigated the efficacy and safety novel noninvasive transnasal evaporative cooling device (CoolStat™). Eleven Yorkshire pigs underwent hypothermia therapy using CoolStat device. induces by blowing dehumidified ambient air over nasal turbinates unidirectional fashion. CoolStat's were assessed...
Abstract Aims Prior studies identified a relationship between epicardial bipolar and endocardial unipolar voltage. Whether the is valid with smaller multielectrode mapping catheters has not been reported. We explored association of right ventricular (RV) voltage using catheter. Methods Electrograms from patients who underwent RV electroanatomical during ablation procedures were analyzed. Each point was matched to corresponding nearest point. The correlation determined. optimal threshold...