A5052893081- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- interferon and immune responses
- Aquaculture disease management and microbiota
- Liver Disease Diagnosis and Treatment
- Nutritional Studies and Diet
- Animal Virus Infections Studies
- Heavy Metal Exposure and Toxicity
- Aluminum Alloys Composites Properties
- Gut microbiota and health
- Toxic Organic Pollutants Impact
- Fusion materials and technologies
- Nuclear Materials and Properties
- Per- and polyfluoroalkyl substances research
- Carcinogens and Genotoxicity Assessment
- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Mercury impact and mitigation studies
- Immune Response and Inflammation
- Birth, Development, and Health
- Climate Change and Health Impacts
- Health, Environment, Cognitive Aging
- Metal Forming Simulation Techniques
- Alcohol Consumption and Health Effects
- Epigenetics and DNA Methylation
The Fourth People's Hospital
2024-2025
Guangxi Medical University
2025
State Key Laboratory of Food Science and Technology
2024
Jiangnan University
2023-2024
Nanjing Medical University
2014-2024
Huazhong University of Science and Technology
2023-2024
Norwegian University of Life Sciences
2012-2024
Capital Medical University
2022-2024
Peking University
2024
Jiangsu Province Hospital
2021-2024
Abstract p,p’-dichlorodiphenyldichloroethylene (p, p’-DDE) and β-hexachlorocyclohexane (β-HCH) were two predominant organochlorine pesticides (OCPs) metabolites in human body associated with disorders of fatty acid metabolism. However, the underlying mechanisms have not been fully clarified. In this study, adult male C57BL/6 mice exposed to low dose p, p’-DDE β-HCH for 8 wk. OCPs accumulation organs, hepatic composition, tricarboxylic cycle (TCA) other metabolite profiles analyzed....
Probiotics can alleviate alcoholic liver disease.
Salmonid alphavirus (SAV) is an emerging virus in salmonid aquaculture, with SAV-3 being the only subtype found Norway. Until now, there has been little focus on alpha interferon (IFN-alpha)-induced antiviral responses during infection vivo or vitro fish. The possible involvement of IFN-gamma response to also not known. In this study, two IFNs were cloned and expressed as recombinant proteins (recombinant IFN-alpha [rIFN-alpha] rIFN-gamma) used for studies. a permissive salmon cell line (TO...
Abstract Salmonid alphavirus subtype-3 (SAV-3) infection in Atlantic salmon is exclusively found Norway. The salmonid alphaviruses have been well characterized at the genome level but there limited information about host-pathogen interaction phenomena. This study was undertaken to characterize replication and spread of SAV-3 internal organs experimentally infected subsequent innate adaptive immune responses. In addition, suitability a cohabitation challenge model for this virus also...
Interferons (IFN) are cytokines secreted by vertebrate cells involved in activation of signaling pathways that direct the synthesis antiviral genes. To gain a global understanding genes induced type I IFNs salmonids, we used RNA-seq to characterize transcriptomic changes IFN treatment and salmon alphavirus subtype 3 (SAV-3) infection TO-cells, macrophage/dendritic like cell-line derived from Atlantic (Salmo salar L) head kidney leukocytes. More than 23 million reads generated were de novo...
The gut microbiome is essential for human health due to its effects on disease development, drug metabolism and the immune system. It may also play a role in interaction with environmental toxicants. However, effect of epoxiconazole, fungicide active ingredient from class azoles developed protect crops, abundance composition has never been studied. We put forward hypothesis that changes microbiota be early signs toxicity induced by epoxiconazole.In this study, female rats were fed...