- Liver Disease Diagnosis and Treatment
- Tea Polyphenols and Effects
- Molecular Sensors and Ion Detection
- Synthesis and biological activity
- Advanced biosensing and bioanalysis techniques
- Heme Oxygenase-1 and Carbon Monoxide
- Hepatitis B Virus Studies
- Luminescence and Fluorescent Materials
- Neonatal Health and Biochemistry
- Advanced Nanomaterials in Catalysis
- Adipokines, Inflammation, and Metabolic Diseases
- Inflammasome and immune disorders
- Neuroscience and Neuropharmacology Research
- Transgenic Plants and Applications
- Multicomponent Synthesis of Heterocycles
- Synthesis of heterocyclic compounds
- Medicinal Plants and Neuroprotection
- Gastric Cancer Management and Outcomes
- Alzheimer's disease research and treatments
- Diet and metabolism studies
- Workplace Health and Well-being
- Neurological Disease Mechanisms and Treatments
- Cardiac Ischemia and Reperfusion
- Cancer, Lipids, and Metabolism
- Click Chemistry and Applications
Anhui Agricultural University
2024
Shanxi Datong University
2013-2023
First Hospital of Lanzhou University
2010-2022
Lanzhou University
2010-2022
Hainan Medical University
2021-2022
Weifang Medical University
2014-2019
Weifang University
2019
Zhejiang University
2008-2009
A red molecular probe for carbon monoxide (CO)-specific detection based on palladium-free mediated opening of spirolactam has been applied to establish a safe and powerful method detect image CO changes in biological systems.
Long-term high-fat diet (HFD) will induce dysbiosis and a disturbance of intestinal homeostasis. Large yellow tea polysaccharide (LYP) has been shown to improve obesity-associated metabolic disease via modulation the M2 polarization. However, contribution LYP barrier impairment improvement mechanisms in obesity caused by an HFD are still not clear. In this study, we evaluated impacts on mucosal function microbiota composition HFD-feeding mice. Results exhibited that dietary supplement could...
We aimed to evaluate the whether AFP levels alone is an adequate screening indicator, or a combination of Generally, alpha-fetoprotein (AFP), CA19-9 and CEA could provide better diagnostic tool in detecting asymptomatic patients with primary hepatic cancer (PHC), also correlation degree differentiation serum biomarker levels.We retrospectively reviewed medical records 1362 form 2014-2018 who visited first Affiliated Hospital Zhejiang University, Hangzhou, China for health check-ups were...
Vinyl azides, obtained from the Ugi-type reaction of 2-azido-3-arylacrylic acid, secondary amine, aldehyde, and isocyanide, react with triphenylphosphine to give a variety 4-arylidene-1<i>H</i>-imidazol-5(4<i>H</i>)-ones in high yields via sequential Staudinger intramolecular aza-Wittig reaction.
A reactivity-based fluorescent probe was utilized to selectively detecting Cu<sup>2+</sup>in aqueous solution and living cell.
The on-purpose-modulated dendritic cells (DCs) have shown charming effects on restoring immune regulatory functions in subjects with diseases.This study aims to construct DCs carrying chimerical antigen (Ag) peptides (CAP-DCs) induce interleukin (IL)-17+ inducible Tregs (iTregs) alleviate food allergy (FA) a murine model.In this study, we constructed CAP-DCs. CAP is fusion protein, consisting of segment recombinant scFv anti-DEC205 antibody and an ovalbumin (OVA) epitope (IC). A OVA-FA model...
Two efficient, scalable routes to bis-1,2,4-oxadiazole have been developed by tandem Staudinger/aza-Wittig reaction from the same starting material diaziglyoxime, isocyanates and triphenylphosphonium in good yields.Two convenient efficient for synthesizing diamino derivatives of bis-1,2,4- oxadiazoles were described.This study provides a simple protocol synthesis bis-1,2,4-oxadiazoles.The two procedures based on triphenylphosphonium.In method I, diaziglyoxime 1 was treated with various...
Objective To observe the therapeutic effects of co-administration γ-aminobutyric acid (CABA), sodium dimercaptopropane sulfonate (Na-DMPS) and vitamin B6 in large doses on liver heart rats with acute tetramine intoxication, compare their separate either GABA or Na-DMPS alone those triad combination. Method Thirty were randomized into control group (n = 6), intoxication without treatment treated 6) combination (GABA + B6, GNDV n group. Samples blood, tissue collected immediately two hours...
A new and simple bis-schiff probe base 1, consisting of 3,3'-diaminodiphenyl sulfone salicylaldehyde moieties as responsive bidentate ligand has been synthesized characterized. The 1 displayed a significant fluorescence enhancement at 503 nm dramatic color change from colorless to green alkaline pH, which can detect Zn2+ by the naked eye. Significantly, sensor exhibits remarkably rapid response high selectivity towards in DMF/H2O solution presence other common metal ions pH 8-13. detection...
Objective To investigate whether there is an association between the expression of B7-HI in HBV transgenic mice and immune tolerance to HBV. Methods T cells stimulatory capacity DC was analyzed using mixed lymphocyte reaction. Expression MHC-Ⅱ, CD80, CD86, B7-H1 on detected by Flow Cytometry. IL-2, IFN γ, IL-10 production were determined ELISA. mRNA protein liver tissue RT-PCR Western blotting respectively. Results The ability from stimulate cell proliferation significantly impaired compared...