A5071766347- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Medicinal Plants and Bioactive Compounds
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Ferroptosis and cancer prognosis
- Liver Disease Diagnosis and Treatment
- Antioxidant Activity and Oxidative Stress
- Metabolomics and Mass Spectrometry Studies
- Genetics and Physical Performance
- Lipid metabolism and disorders
- Bioactive Natural Diterpenoids Research
- Coastal and Marine Management
- Bioinformatics and Genomic Networks
- Biochemical and biochemical processes
- Sphingolipid Metabolism and Signaling
- Genomics, phytochemicals, and oxidative stress
- Korean Urban and Social Studies
- COVID-19 Clinical Research Studies
Xinjiang Medical University
2013-2025
Xinjiang Technical Institute of Physics & Chemistry
2024-2025
Sichuan University
2016-2025
West China Hospital of Sichuan University
2025
National Marine Environmental Forecasting Center
2024
National Institute for Viral Disease Control and Prevention
2013-2024
Center for Disease Control
2024
Wuhan University of Science and Technology
2016-2024
Chinese Center For Disease Control and Prevention
2015-2024
Xiamen University
2022-2024
Abstract Emerging in December 2019, coronavirus disease 2019 (COVID-19) eventually became a pandemic and has posed tremendous threat to global public health. However, the origins of SARS-CoV-2, causative agent COVID-19, remain be determined. It reported that certain number early case clusters had contact history with Huanan Seafood Market. Therefore, surveillance SARS-CoV-2 within market is vital importance. Herein, we presented detection results 1380 samples collected from environment...
Background Excessive exposure to light enhances the progression and severity of some human retinal degenerative diseases. While microglia are likely be important in neuron damage associated with these diseases, relationship between photoreceptor microglial activation remains poorly understood. Some recent studies have indicated that chemokine fractalkine is involved pathogenesis many neurodegenerative The present study was performed investigate cross-talk injured photoreceptors activated...
We identified the effective components and underlying mechanisms of Quince (Cydonia oblonga Mill, COM) extract against atherosclerosis. The COM were with UHPLC-Q-TOF-MS/MS. Network pharmacology was performed. A rat model atherosclerosis induced by high-fat emulsion combined vitamin D3 established. anti-atherosclerosis effect evaluated from various aspects such as blood lipid regulation, anti-oxidative stress, anti-inflammatory response, vascular protection function. 14 serum using Through...
Tuberculosis (TB) is a major infectious disease with significant public health implications. Its widespread transmission, prolonged treatment duration, notable side effects, and high mortality rate pose severe challenges. This study examines the epidemiological characteristics of TB globally across regions, providing scientific basis for enhancing prevention control measures worldwide.
In China, hepatitis E virus (HEV) is prevalent and causes disease, but its epidemiological profile not well understood. We used a commercial enzyme-linked immunosorbent assay to detect total antibodies in 15,862 serum samples collected during the Third National Viral Hepatitis Prevalence Survey. The results were analyzed calculate estimates of HEV seroprevalence examine effects some putative risk factors. general Chinese population period from 2005 through 2006 was 23.46% (95% confidence...
Abstract Background Lignocellulosic biomass has been commonly regarded as a potential feedstock for the production of biofuels and biochemicals. High sugar yields complete bioconversion all lignocellulosic sugars into valuable products are attractive utilization lignocelluloses. It is essential to pretreat hydrolyze lignocelluloses at high solids loadings during industrial processes, which more economical environmentally friendly capital cost, energy consumption, water usage can be reduced....
Abstract Post-translational modifications (PTMs) of the non-histone protein high-mobility group B1 (HMGB1) are involved in modulating inflammation and immune responses. Recent studies have implicated that RNA-binding (RBP) Musashi-2 (MSI2) regulates multiple critical biological metabolic immunoregulatory functions. However, precise role MSI2 regulating PTMs tumor immunity colorectal cancer (CRC) remains unclear. Here, we present data indicating potentiates CRC immunopathology...
Abstract: FTY720 is an analog of sphingosine-1-phosphate (S1P) derived from the ascomycete Cordyceps sinensis. As a new immunosuppressant, widely used to treat multiple sclerosis. binds S1P receptor after phosphorylation, thereby exerting immunosuppressive effects. The nonphosphorylated form can induce cell apoptosis, enhance chemotherapy sensitivity, and inhibit tumor metastasis tumors by inhibiting SPHK1 (sphingosine kinase 1) activating PP2A (protein phosphatase 2A) various death...
Waste paper was studied as a potential source for lipid production using the oleaginous yeast Cryptococcus curvatus first time. Three common types of waste paper, office newspaper, and cardboard, were directly hydrolyzed by an enzyme cocktail to generate sugar-rich nitrogen-limited hydrolysates. When these hydrolysates used without any auxiliary nutrients C. curvatus, content yield higher than 50% 200 mg/g, respectively. The nitrogen-rich exerted no negative effects on production. Moreover,...
Musashi-2 (MSI2) is a critical RNA-binding protein (RBP) whose ectopic expression drives the pathogenesis of various cancers. Accumulating evidence suggests that inducing ferroptosis tumor cells can inhibit their malignant biological behavior as promising therapeutic approach. However, it unclear whether MSI2 regulates cell death in colorectal cancer (CRC), especially underlying mechanisms and effects CRC remain elusive.Experimental methods including qRT‒PCR, immunofluorescence, flow...
Previous observational studies have shown that Hypothyroidism is associated with Von Willebrand Disease (VWD), but the causal relationship has not been confirmed because of conflicting findings and confounding by mixing factors. There are also some suggesting polyunsaturated fatty acids (PUFA) may be one potential mediators. In this study, we used a Mendelian randomization study to analyze between VWD investigate whether mediate effects on VWD. Using large publicly available genome-wide...