- Advanced Proteomics Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Chemical Synthesis and Analysis
- Mass Spectrometry Techniques and Applications
- Water resources management and optimization
- Aquaculture Nutrition and Growth
- Biochemical effects in animals
- Advanced Photocatalysis Techniques
- Enzyme Structure and Function
- Vehicle emissions and performance
- Evaluation Methods in Various Fields
- Public-Private Partnership Projects
- Landslides and related hazards
- Neutropenia and Cancer Infections
- Water-Energy-Food Nexus Studies
- Reproductive biology and impacts on aquatic species
- Geotechnical Engineering and Analysis
- Air Quality and Health Impacts
- Dialysis and Renal Disease Management
- Luminescence and Fluorescent Materials
- Public Procurement and Policy
- Transportation Systems and Logistics
- Transboundary Water Resource Management
- Microplastics and Plastic Pollution
- Evaluation and Optimization Models
Nanjing Medical University
2025
Songshan Lake Materials Laboratory
2023-2024
Beijing Normal University
2023-2024
Sichuan University
2019-2024
Yan'an University
2024
Guangzhou Center for Disease Control and Prevention
2024
North China Municipal Engineering Design & Research Institute
2021-2023
Chengdu University
2020-2021
Sun Yat-sen University
2015
Delft University of Technology
2014
To date, abundant strategies and affinity materials are proposed to enrich phosphopeptides glycopeptides from biological systems. However, few can meet the demand for enriching both with an integrated single material. In this work, a novel magnetic metal–organic framework nanocomposite Zr4+ ions as metal unit well terephthalic acid (PTA) 1,4-phenylenebisboronic (denoted PBA) dual organic ligands was designed fabricated highly efficient enrichment of glycopeptides. It is worth mentioning that...
Atomically dispersed metal sites anchored on nitrogen-doped carbonaceous substrates (M-NCs) have emerged as promising alternatives to conventional peroxymonosulfate (PMS) activators; however, the exact contribution of each site still remains elusive. Herein, isolated Fe-N4 active site-decorated three-dimensional NC (FeSA-NC) via a micropore confinement strategy are fabricated initiate PMS oxidation reaction, achieving specific activity 5.16 × 103 L·min-1·g-1 for degradation bisphenol A...
Highly specific enrichment of phosphopeptides from complex biological samples was a precondition for further studying its physiological and pathological processes due to the important trace amounts phosphopeptides. In this work, phytic acid (PA) functionalized magnetic cerium zirconium bimetallic metal-organic framework nanocomposites (denoted as Fe3O4@SiO2@Ce-Zr-MOF@PA) were fabricated by facile yet efficient method. The as-prepared nanomaterial exhibited high sensitivity (0.1 fmol μL-1),...
This study aimed to evaluate mecapegfilgrastim utilization for the prophylaxis of chemotherapy-induced neutropenia in cancer patients and assess changes caused by National Health Insurance Coverage (NHIC) policy. Individual patient data, including demographics, medical insurance status, type, tumor stage, were extracted from electronic records an oncology specialty tertiary hospital Jiangsu Province, China. An interrupted time series (ITS) analysis with a segmented regression model was...
The aging behavior of microplastics (MPs) in the environment has garnered significant attention, yet exact process undergone by during advanced oxidation still remains unclear. This study emphasized elucidating and dechlorination mechanisms polyvinyl chloride (PVC MPs) within UV-activated sodium percarbonate system (UV/SPC). After 35 h UV/SPC (0.05 M) treatment, it exhibited effective with a Cl− release 100.62 ± 13.17 mg/L. And this treatment resulted fragmentation fragments from PVC MPs,...
Selective capture of mono-, multi- or global phosphopeptides is significant for the in-depth study protein kinase phosphatase signal transduction pathways. However, this largely restricted because lack versatile affinity materials with high enrichment capacity and tunable selectivity. Here, we prepared a smart nanoprobe selective by introducing polyamidoamine dendrimer (PAMAM)-grafted poly(methacrylic acid) (PMAA) brushes to modified magnetic composite nanospheres (denoted as...
A ten-week feeding trail was conducted to investigate the effects of increasing DL-methionine (Met) supplementation on success fish meal (FM) replacement with plant proteins in practical diets for juvenile gibel carp, Carassius auratus gibelio. Twelve isoenergetic were formulated including two 150 g kg−1 FM (Diet 1—positive control 1 reflecting a commercial diet and Diet 2—positive 2 but balanced essential amino acid (EAA) profile) ten 50 (negative controls) supplemented graded levels (0–3.0...
Hydrolyzed fish proteins (H-pro) contains high concentrations of free amino acids and low molecular peptides that potentially benefit health. The following study aimed to test whether the water soluble phase H-pro could reduce apoptosis inflammation in primary liver cells isolated from Atlantic salmon H2O2 provoked oxidative stress. Cells were grown as monocultures or co-cultured with head kidney assess possible cross talk metabolism during treatments. media without for 2 days before being...
A novel smart polymer functionalized magnetic nanocomposite microsphere as an ideal platform to efficiently enrich both mono-phosphopeptides and multiple-phosphopeptides without distinction from complex biological samples.
Design and preparation of magnetic polymer nanomaterials their application in bioseparation.
Morin is a flavonol with beneficial effects on diabetic-related injuries. However, the effect of morin diabetic cardiomyopathy and its association autophagy, apoptosis, inflammation, oxidative stress remains unclear. The current study aimed to reveal mechanisms underlying morin-mediated protection against cardiac failure in rats.
Abstract While China’s economy is developing rapidly and sustainably, urban issues appears continuously, for instance traffic congestion, insufficient funds, environmental pollution, housing shortages. It necessary to learn from advanced international countries’ experiences process planning in accordance with the domestic situation. This article analyses relationship between transportation land use, proposes basic idea of applying concept coordinated development by introducing experience...
The main purpose of this study is to analyze the side slip vehicles on freeway under cross wind, and establish a calculation method safe driving speed wind. vehicle dynamics model used condition wind freeway, studied basis. Firstly, based comprehensive consideration speed, type, road stability four typical in China analyzed; Then, speeds different types are calculated. results show that action greater is, risk is. On an appropriate limit needed ensure safety conditions.
The green ecological evaluation of municipal roads has the characteristics multi-attribute, multi-level, and difficult to quantify. Traditional methods often ignore ambiguity randomness, results are subjective one-sided. A new method is needed break through limitations traditional methods. This paper constructs an index system from five aspects: environment protection, quality improvement, safety efficiency, low-carbon, information intelligence, comprehensively uses AHP-entropy weight...
Abstract In recent years, a three-dimensional numerical simulation has been widely used in the analysis of slope stability. this paper, landslide is as engineering background, and FLAC3D software to analyze stable state landslide. The relationship between displacement time step point analyzed. position sliding surface simulated, comprehensively evaluated, thereby providing meaningful experience for other similar projects.
The objective of this study was to evaluate the impact finasteride on progression prostate intraepithelial neoplasia and levels prostate-specific antigen (PSA) in patients. A total 120 patients with high-grade prostatic were included from January 2013 2018. All underwent biopsies. Among them, 60 assigned observation group received a daily dosage 5 mg for months, while remaining control did not receive finasteride. PSA measured every six imaging scans conducted throughout five-year period....