A5003021411- Pancreatic function and diabetes
- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Pluripotent Stem Cells Research
- Diabetes Management and Research
- Physics of Superconductivity and Magnetism
- Diabetes and associated disorders
- RNA Interference and Gene Delivery
- Xenotransplantation and immune response
- Tissue Engineering and Regenerative Medicine
- Cannabis and Cannabinoid Research
- Advanced Condensed Matter Physics
- CRISPR and Genetic Engineering
- Mesenchymal stem cell research
- Magnetic and transport properties of perovskites and related materials
- Supercapacitor Materials and Fabrication
- Virus-based gene therapy research
- Superconducting Materials and Applications
- Genetics and Neurodevelopmental Disorders
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Renal Transplantation Outcomes and Treatments
- Liver Disease and Transplantation
- Advancements in Battery Materials
- Electrospun Nanofibers in Biomedical Applications
Okayama Saidaiji Hospital
2012-2024
Tokai University
2024
Tokyo Medical and Dental University
2024
Tohoku University
2000-2023
Tokyo University of Pharmacy and Life Sciences
2023
Northwest African American Museum
2023
Shinshu University
2011-2021
University of Hyogo
2021
Tokushima University
2021
National Institute of Technology, Nagano College
2020
Low-cost supercapacitors have the ability to rapidly store a large amount of charge, which makes them best alternative batteries in portable electronics. Here, we demonstrate fabrication all-carbon using an organic electrolyte. By ZIF-derived nanoporous carbon electrodes, realized high-performance supercapacitor cell 2 M NEt4BF4/PC as Our device shows good energy storage capacity that is comparable other previously reported supercapacitors.
Abstract Single metal-organic frameworks (MOFs), constructed from the coordination between one-fold metal ions and organic linkers, show limited functionalities when used as precursors for nanoporous carbon materials. Herein, we propose to merge advantages of zinc cobalt metals into one single MOF crystal ( i.e. , bimetallic MOFs). The linkers that coordinate with tend yield graphitic carbons after carbonization, unlike those bridging ions, due controlled catalytic graphitization by...
Hitherto, many reports on composite materials for electrochemical applications are based one-dimensional carbon nanotubes or two-dimensional graphene materials. However, these usually suffer from a stacking problem during cycling. A smart nanoarchitectural design is needed in order to overcome this problem. Recent research energy storage (EES) has focused the development of three-dimensional (3-D) core-shell structures. The basis high performance control efficient intercalation ions such 3-D...
Super-stable mesoporous carbon sheet made of edge-free graphene walls enabled the assembly symmetric supercapacitors with excellent stability under 3.5 V@60 °C and 4.4 V@25 conditions, even a conventional electrolyte.
Because of a critical shortage in suitable organs, many patients with terminal liver disease die each year before transplantation can be performed. Transplantation isolated hepatocytes has been proposed for the temporary metabolic support awaiting or spontaneous reversion their disease. A major limitation this form therapy is present inability to isolate an adequate number transplantable hepatocytes. highly differentiated cell line, NKNT-3, was generated by retroviral transfer normal primary...
Abstract Purpose: Replication-selective tumor-specific viruses present a novel approach for treating neoplastic disease. These vectors are designed to induce virus-mediated lysis of tumor cells after selective viral propagation within the tumor. Telomerase activation is considered be critical step in carcinogenesis, and its activity closely correlated with human telomerase reverse transcriptase (hTERT) expression. We investigated antitumor effect hTERT-specific replication-competent...
A novel cuprate Volborthite, Cu3V2O7(OH)2-2H2O, containing an S-1/2 (Cu 2+ spin) kagome-like lattice is studied by magnetic susceptibility, specific heat, and 51 V NMR measurements. Signs for neither long-range order nor spin-gapped singlet ground states are detected down to 1.8 K, in spite of large antiferromagnetic couplings ~100 K between Cu spins forming a two-dimensional network. It suggested that Volborthite represents system close quantum critical point classical ordered disordered phases.
Single-phase α''-Fe16N2 nanoparticles have been synthesized with high reproducibility in gram amounts for the first time. The were obtained through various kinds of successive procedure starting from reduction Fe-oxides, followed by nitriding an atmosphere very low moisture and oxygen contents less than 1 ppm entire process. single-phase exhibited saturation magnetization (Ms) 234 emu/g at 5 K a magnetocrystalline anisotropy constant (Ku) 9.6×106 erg/cm3. These magnetic properties this...
The carbon corrosion sites at positive electrodes of supercapacitors are identified as H-terminated edge sites, ether, hydroxyl and carbonyl groups.
The secretory leukoprotease inhibitor (SLPI) gene codes for a 12-kD protein that within the lung protects airway epithelium from neutrophil elastase. Screening of 228 alleles in 114 individuals sequence differences by RNase protection genomic DNA revealed no detectable polymorphisms SLPI exons II-IV. expression was demonstrated identifying mRNA transcripts bronchial epithelial cells freshly isolated normals. Cell lines derived mucosal surfaces (HS-24 squamous cell carcinoma, HeLa cervical...
Hepatocyte transplantation improves the survival of laboratory animals with experimentally induced acute liver failure and physiological abnormalities associated liver-based metabolic deficiencies. The role hepatocyte in treating decompensated cirrhosis, however, has not been studied depth. To address this issue, cirrhosis was using phenobarbital carbon tetrachloride (CCL(4)) were only when evidence did improve CCL(4) held for 4 weeks. Animals received intrasplenic syngeneic rat hepatocytes...
Background. Cholangiocytes perform an essential role in important pathophysiologic functions the liver. Establishment of a human cholangiocyte line facilitates advances research and clinical applications for cell therapies. Here, we describe immortalization cholangiocytes using serial transfection simian virus 40 large T (SV40T) followed by telomerase reverse transcriptase (hTERT). Methods. SV40T-transduced liver OUMS-21 cells were superinfected with retroviral vector SSR#197 encoding hTERT...
Artificial bones have often used for bone regeneration due to their strength, but they cannot provide an adequate environment cell penetration and settlement. We therefore attempted explore various materials that may allow the cells penetrate engraft in defects. PuraMatrix is a self-assembling peptide scaffold produces nanoscale allowing both cellular engraftment. The objective of this study was investigate effect on mouse defect model calvaria. Matrigel as control. expression bone-related...