Y. Zhu

ORCID: 0000-0003-2649-7900
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Vibration Control and Rheological Fluids
  • Vibration and Dynamic Analysis
  • Pregnancy and preeclampsia studies
  • Magnetic Bearings and Levitation Dynamics
  • Magneto-Optical Properties and Applications
  • Head and Neck Cancer Studies
  • Reproductive System and Pregnancy
  • Advanced Fiber Optic Sensors
  • Lung Cancer Diagnosis and Treatment
  • High voltage insulation and dielectric phenomena
  • Microplastics and Plastic Pollution
  • Metastasis and carcinoma case studies
  • Underground infrastructure and sustainability
  • Plasmonic and Surface Plasmon Research
  • Evacuation and Crowd Dynamics
  • Birth, Development, and Health
  • Fault Detection and Control Systems
  • Cancer-related Molecular Pathways
  • Cancer Diagnosis and Treatment
  • Ship Hydrodynamics and Maneuverability
  • Transboundary Water Resource Management
  • Lung Cancer Research Studies
  • Wireless Sensor Networks for Data Analysis
  • Power Transformer Diagnostics and Insulation

Wenzhou Medical University
2025

Wuhan University of Technology
2025

Fujian Agriculture and Forestry University
2023-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Second Hospital of Nanchang
2024

Shanghai Jiao Tong University
2019-2023

International Peace Maternity & Child Health Hospital
2021-2023

Shanghai Sixth People's Hospital
2023

First Affiliated Hospital of Zhengzhou University
2020-2022

Shanxi Medical University
2021

Microplastics (MPs), which are emerging as a new type of environmental pollutants, have raised great concerns regarding their threats to human health. A successful pregnancy depends on the sophisticated regulation maternal-fetal immune balance, but risks polystyrene MP (PS-MP) exposure in early remain unclear. In this study, we exposed C57BL/6-mated BALB/c mice PS-MP particles and used flow cytometry explore towards system. Herein, allogeneic mating murine model showed an elevated embryo...

10.1016/j.reprotox.2021.10.002 article EN cc-by-nc-nd Reproductive Toxicology 2021-10-07

Rhodococcus opacus strain PD630 (R. PD630), is an oleaginous bacterium, and also one of few prokaryotic organisms that contain lipid droplets (LDs). LD important organelle for storage but intercellular communication regarding energy metabolism, yet a poorly understood cellular organelle. To understand the dynamics using simple model organism, we conducted series comprehensive omics studies R. including complete genome, transcriptome proteome analysis. The genome encodes 8947 genes are...

10.1093/nar/gkt932 article EN Nucleic Acids Research 2013-10-22

The myelin-derived neurite growth inhibitor Nogo has been proposed to play a major role in blocking axon regeneration the CNS after injuries. However, past studies have produced mixed results regarding regenerative phenotype of various Nogo-deficient mouse lines experimental spinal cord injury. Two did not display enhanced corticospinal tract (CST) regeneration, and one displayed modest regeneration. A fourth line, Nogo-A,B gene-trap mutant, was instead reported exhibit extensive CST but...

10.1523/jneurosci.1864-09.2009 article EN Journal of Neuroscience 2009-07-08

Abstract Disruption of the intestinal epithelial barrier, driven by imbalances in gut mucosal immunity and microbial homeostasis, is central to onset progression inflammatory bowel disease (IBD). This study introduces a CO‐releasing polyoxometalates (POMs) nanozyme (PMC), synthesized coordinating pentacarbonyl manganese bromide with molybdenum‐based POM nanoclusters. PMC demonstrates targeted accumulation at IBD‐affected sites, efficient scavenging reactive oxygen species (ROS), responsive...

10.1002/advs.202500116 article EN cc-by Advanced Science 2025-03-13

Abstract Dysregulated trophoblast proliferation, invasion, and apoptosis may cause several pregnancy‐associated complications, such as unexplained recurrent spontaneous abortion (URSA). Recent studies have shown that metabolic abnormalities, including glycolysis inhibition, dysregulate function, leading to URSA. However, the underlying mechanisms remain unclear. Herein, we found lactate dehydrogenase A (LDHA), a key enzyme in glycolysis, was significantly reduced placental villus of URSA...

10.1096/fj.202201219rr article EN The FASEB Journal 2022-12-30

10.1016/j.simpat.2024.102929 article EN Simulation Modelling Practice and Theory 2024-03-24

Single-molecule semiconductor nanomaterials with π-stacked structures in solution and the solid state are prepared from a polystyrene backbone densely tethered π-conjugated polyquinoline side chains (see figure). Highly structured optical absorption spectra exclusive broad, structureless yellow excimer emission toluene solutions confirm collective properties of side-chain conjugated polymers.

10.1002/adma.200601530 article EN Advanced Materials 2007-01-25

Background: Osimertinib (AZD9291) is a third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that has demonstrated significant clinical benefits in patients with EGFR sensitizing mutations or T790M mutation. However, approximately 5% to 15% of non-small-cell lung cancer (NSCLC) mutation primary resistance osimertinib treatment. The underlying mechanism unknown. Methods: A total 117 stage IIIb-IV EGFR-T790M NSCLC were undergoing tumor biopsies blood withdrawing by...

10.1093/annonc/mdz063.012 article EN publisher-specific-oa Annals of Oncology 2019-04-01

Abnormal trophoblast function is associated with diseases such as recurrent spontaneous abortion, pre-eclampsia, and preterm birth, endangers maternal fetal health. However, the underlying regulatory mechanisms remain unclear. In this study, we found DOCK1 expression decreased in placental villi of patients that its determined invasive properties extravillous trophoblasts (EVTs), highlighting a previously unknown role regulating EVT function. Furthermore, deficiency disturbed ubiquitinated...

10.26508/lsa.202302247 article EN cc-by Life Science Alliance 2023-11-15

A large proportion of the fluctuating propulsion forces transmit to hull structure an underwater vehicle through stern support and cause structural vibration sound radiation. To reduce influence dynamic on structure, a control method that uses active orthogonal is proposed. The arranged in vertical horizontal directions connect bearing equipped with electromagnetic actuators generate counter forces. shaft–hull-coupled system used investigate effectiveness support, numerical results indicate...

10.1177/1077546321993583 article EN Journal of Vibration and Control 2021-02-16

A high-performance wide-angle refractive index sensor based on a simple onedimensional (1D) metallic deep nanogroove array with high aspect ratio is experimentally fabricated and demonstrated. The 1D groove featured by the excitation of magnetic plasmon (MP), referring to an effective coupling incident electromagnetic waves strong response induced inside grooves. Utilizing MP resonances that are extremely sensitive surrounding dielectric medium, we successfully achieve sensitivity (RIS) up...

10.1364/oe.26.034122 article EN cc-by Optics Express 2018-12-17

Purpose The development of urban underground complexes (UUCs) has great positive significance for improving safety. Therefore, it is necessary to identify the key factors people's behavior evacuation route selection (BERS) fire emergencies and UUCs’ development. This study aims find out affecting BERS in process UUCs. Design/methodology/approach To achieve this goal, authors conducted a field experiment F City. Furthermore, are obtained by using structural equation model compared with test...

10.1108/ecam-04-2022-0290 article EN Engineering Construction & Architectural Management 2023-02-08

Presents a fuzzy and neural network integrated intelligence approach for fault diagnosis monitoring. A generalized probability sum operator product are proposed to implement the model inference. nonlinear approximation based on feedforward networks is constructed achieve input fuzzification of networks. Further, an application system designed condition monitoring marine diesel engine simulations reasoning discussed.

10.1049/cp:19980361 article EN 1998-01-01

Interferometry-based online partial discharge (PD) monitor presented in this paper can detect the occurrence of PD sensitively, evaluate peak value inception voltage with random waveform and damage extent relatively cost effectively. The interferograms affected by are collected online. By extracting phase information interference fringes quantitatively, be retrieved real-time. Merits proposed method as an quantitative validated via theoretical analysis well experimentations use artificially...

10.1038/s41598-020-76134-x article EN cc-by Scientific Reports 2020-11-04

Abstract. Syria is one of the Middle Eastern countries that suffer from scarcity in water resources availability, which affects growth and development economic activities. In this research, Water Evaluation Planning (WEAP) model applied to evaluate future demand Euphrates Aleppo basin (EAB), Syria, by taking into account climate change may affect domestic, industrial, agricultural sectors until 2050. The projections temperature precipitation were assessed using a new version MAGICC/SCENGEN...

10.5194/piahs-364-307-2014 article EN cc-by Proceedings of the International Association of Hydrological Sciences 2014-09-16

To perceive the advent of pulse current (PC) sensitively and evaluate peak value accurately on a cost effective setup, an interferometric measurement is proposed first in this study. By extracting phase information interference fringes effected by PC quantitatively, relative with random waveform obtained real time. Based theoretical analysis, method has been tested 8/20 μs 3, 2.75 2.5 kA. The interferograms are collected online, recovery completed seconds. Repetitive experiments under same...

10.1049/iet-pel.2019.0279 article EN IET Power Electronics 2019-08-10
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