Enver Kamil Akcan

ORCID: 0000-0003-2682-6241
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About
Contact & Profiles
Research Areas
  • Biochemical and Molecular Research
  • Enzyme Structure and Function
  • Protein Structure and Dynamics
  • Porphyrin Metabolism and Disorders

Istanbul Technical University
2022-2023

Koç University
2022-2023

X-ray crystallography is a robust and powerful structural biology technique that provides high-resolution atomic structures of biomacromolecules. Scientists use this to unravel mechanistic details biological macromolecules (e.g., proteins, nucleic acids, protein complexes, protein-nucleic acid or large compartments). Since its inception, single-crystal cryocrystallography has never been performed in Türkiye due the lack diffractometer. The diffraction facility recently established at...

10.55730/1300-0152.2637 article EN TURKISH JOURNAL OF BIOLOGY 2023-01-01

Abstract High-resolution biomacromolecular structure determination is essential to better understand protein function and dynamics. Serial crystallography an emerging structural biology technique which has fundamental limitations due either sample volume requirements or immediate access the competitive X-ray beamtime. Obtaining a high of well-diffracting, sufficient-size crystals while mitigating radiation damage remains critical bottleneck serial crystallography. As alternative, we...

10.1038/s41598-023-33989-0 article EN cc-by Scientific Reports 2023-05-19

Abstract X-ray crystallography is a robust and powerful structural biology technique that provides high-resolution atomic structures of biomacromolecules. Scientists use this to unravel mechanistic details biological macromolecules (e.g. proteins, nucleic acids, protein complexes, protein-nucleic acid or large compartments). Since its inception, single-crystal cryo-crystallography has never been performed in Türkiye due the lack diffractometer. The diffraction facility recently established...

10.1101/2022.09.03.506456 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-09-05

ABSTRACT High-resolution biomacromolecular structure determination is essential to better understand protein function and dynamics. Serial crystallography an emerging structural biology technique which has fundamental limitations due either sample volume requirements or immediate access the competitive X-ray beamtime. Obtaining a high of well-diffracting, sufficient-size crystals while mitigating radiation damage remains critical bottleneck serial crystallography. As alternative, we...

10.1101/2022.10.12.511637 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-10-17
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