The pattern of gastric cancer in the Western world is changing, with an increased proportion tumours upper stomach. aim this study was to investigate changes clinicopathological features and survival patients resected at a single institution, area high incidence Far East.Clinical pathological findings were compared who underwent gastrectomy Seoul National University Hospital during four consecutive periods (1986-1990, 1991-1995, 1996-2000 2001-2006).There 12 026 patients. mean age from 53·4...

Recent advances in next-generation sequencing technologies have enabled comprehensive analysis of the gut microbiota, which is closely linked to health host. Consequently, several studies explored factors affecting microbiota composition. In recent years, increasing number dog owners are feeding their pets a natural diet i.e., one consisting bones, raw meat (such as chicken and beef), vegetables, instead commercial feed. However, effect these diets on dogs (Canis lupus familiaris) unclear....

Nodal staging for gastric cancer according to the 1997 Union Internacional Contra la Cancrum tumour node metastasis classification is based on number of metastatic lymph nodes. The aim this study was evaluate whether nodes examined affected cancer.A retrospective performed in 4789 consecutive patients with cancer, who had undergone curative resection (R0) from 1986 1995. Patients were classified examined. and stage-stratified survival compared.There significant differences stage IIIA between...

Introduction We systematically tracked early life stages in a military dog birth cohort to investigate canine gut microbiota dynamics related environmental exposure during growth. This study utilized 16s rRNA amplicon sequencing-based analysis with molecular epidemiology of Enterococcus faecalis within controlled environment at training center. Methods examined shifts diversity and taxonomic composition across four growth (lactation, weaning, starter, puppy) three littermate groups....

Campylobacter jejuni is a major foodborne pathogen that increasingly found worldwide and transmitted to humans through meat or dairy products. A detailed understanding of the prevalence characteristics C. in cattle farms, which are likely become sources contamination, imperative currently lacking. In this study, total 295 farm samples from 15 farms (24 visits) Korea were collected. at level was 60% (9/15) animal 23.8% (68/266). Using multivariable generalized estimating equation model based...

In Arabidopsis mature seeds, the onset of embryo-to-seedling transition is nonautonomously controlled, being blocked by endospermic abscisic acid (ABA) release under unfavorable conditions. Whether endosperm governs additional nonautonomous developmental processes during this unknown. Mature embryos have a more permeable cuticle than seedlings, consistent with their ABA uptake capability. Seedlings acquire well-sealing cuticles adapted to aerial lifestyle germination. Endosperm removal...

As a primary source of Shiga-toxin-producing Escherichia coli (STEC) infection, cattle are often targeted to develop strategies for reducing STEC contamination. Monitoring the virulence potentials isolates from is important tracing contamination sources, managing outbreaks or sporadic cases, and risks human infection. This study aimed investigate prevalence in farm samples South Korea assess their potentials.In total, 63 were isolated 496 samples, temperature rainfall affected (p < 0.001)....

Red ginseng, widely used in traditional medicine for various conditions, imparts health benefits mainly by modulating the gut microbiota humans. Given similarities between humans and dogs, red ginseng-derived dietary fiber may have prebiotic potential dogs; however, its effects on dogs remain elusive. This double-blinded, longitudinal study investigated impact of ginseng host response dogs. A total 40 healthy household were randomly assigned to low-dose (n = 12), high-dose 16), or control...

SUMMARY Epidemiological and virological studies indicate that noroviruses-contaminated groundwater was the primary source of four acute gastroenteritis outbreaks in South Korea between 2008 2012. Furthermore, cabbage kimchi first identified as vehicle transmission infected patients an outbreak 2011. The proper treatment sources prior to use for drinking or food preparation is necessary prevent further outbreaks.

In Korea, there is a need for research on human–animal relationships because of an increase in the number companion animals and positive changes public perception toward them. Few studies have examined these changes. This epidemiological study investigates characteristics Korean dog owners their pet dogs identifies owner- dog-dependent factors that influence owners' attitudes pets. We conducted cross-sectional by asking them to complete Pet Attitude Scale-based questionnaire about...

Abstract Background This study aimed to determine the appropriate extent of lymph node (LN) dissection in gastric cancer by analysing LN metastasis patterns from prospectively collected topographical data on nodal status at Seoul National University Hospital, Korea. Methods The rate for each station was analysed according depth tumour invasion patients with primary lower-third who underwent curative gastrectomy. Maruyama Index unresected disease (MI) calculated using WinEstimate® program...

Highly Pathogenic Avian Influenza (HPAI) subtype H5N8 outbreaks occurred in poultry farms South Korea 2014 resulting significant damage to the industry. Between and 2016, pandemic disease caused economic loss social disruption. To evaluate risk factors for HPAI infection broiler duck farms, we conducted a retrospective case–control study on farms. Forty-three with confirmed laboratories premises were selected as case group, 43 HPAI-negative designated control group. Control matched based...

Campylobacter , the most common etiologic agent of zoonotic gastroenteritis in humans, is present many reservoirs including livestock animals, wildlife, soil, and water. Previously, we reported a novel jejuni strain SCJK02 (MLST ST-8388) from gut wild mice ( Micromys minutus ) using culture-dependent methods. However, due to fastidious growth conditions presence viable but non-culturable spp., it unclear whether M. reservoir. This study aimed to: 1) determine distribution proportion spp....

The worldwide spread of extended spectrum β-lactamase (ESBL)- and AmpC (AmpC)-producing Escherichia coli poses serious threats to public health. Swine farms have been regarded as important reservoirs ESBL/AmpC-EC. This study aimed determine the prevalence, ESBL/AmpC types, clonal distribution ESBL/AmpC-EC from swine analyze difference according production stages. In addition, we evaluated potential risks clones humans. Individual fecal samples ( n = 292) were collected weaning, growing,...

To evaluate the different expression patterns and prognostic significance of cell cycle regulatory molecules in diffuse large B-cell lymphomas (DLBCLs) germinal centre (GC) non-GC phenotypes.Tissue microarray slides composed 126 extranodal 88 nodal DLBCLs were immunostained for p16, p21, p27, p14 p53. classified into GC phenotype according to immunohistochemical bcl-6, CD10, MUM1. Aberrant p53 was more frequent cases (P = 0.038), loss p21 significantly common 0.004, P 0.001, < 0.001)....

Necrotic enteritis (NE) is a devastating enteric disease caused by Clostridium perfringens type G. One of the pore-forming toxins, NE B-like (NetB) toxin, secreted pathogenic C. G, has been proposed to be main virulent factor in pathogenesis. The present study aimed detect presence NetB toxin biological samples NE-afflicted chickens using NetB-specific monoclonal-based enzyme-linked immunosorbent assay (ELISA). Biological samples, including serum, digesta, and fecal droppings, were obtained...

Cattle are a natural reservoir of Shiga toxin-producing Escherichia coli (STEC) and have recently been recognized as major source Campylobacter jejuni contamination. While several factors known to be associated with bacterial colonization, the underlying microbial not clarified. In this study, we characterized fecal microbiota dairy cattle (n = 24) using next-generation sequencing elucidate intestinal communities diversity in relation presence foodborne pathogens STEC C. (STEC-positive...

Enterococcus spp.are normally present in the gastrointestinal tracts of animals and humans, but can cause opportunistic infections that be transmitted to other or humans with integrated antibiotic resistance.To investigate if this is a potential risk military working dogs (MWDs), we analyzed resistance patterns genetic relatedness spp.isolated from fecal samples MWDs four different age groups.Isolation rates spp., (E.) faecalis, E. faecium, were 87.7% (57/65), 59.6% (34/57), 56.1% (32/57),...

Highly pathogenic avian influenza (HPAI), a zoonotic disease, is major threat to humans and poultry health worldwide. In January 2014, HPAI virus subtype H5N8 first infected farms in South Korea, 393 outbreaks, overall, were reported with enormous economic damage the industry. We analyzed spatiotemporal distribution of outbreaks using global local interaction analyses (January July 2014) second (September 2014 June 2015) outbreak waves. The space–time K-function revealed significant...

Avian coccidiosis is a disease caused by members of the genus Eimeria. Huge economic losses incurred global poultry industry due to have increased need for cost-effective and easily available recombinant vaccines. Microneme protein 2 (MIC2) surface antigen 1 (SAG1) E. tenella been recognised as potential vaccine candidates. However, genetic diversity antigens in field isolates, which affects efficacy, has yet be largely investigated. Here, we analysed natural selection etmic2 etsag1 Korean...

Wild migratory birds are essential for sustaining healthy ecosystems, but the effects of a rehabilitation period on their gut microbiomes still unclear. Here, we performed longitudinal sampling, 16S rRNA sequencing, and antibiotic resistance monitoring microbiome six species wild protected as natural monuments in South Korea that subject to short- or long-term periods. Overall, diversity was significantly decreased early stages rehabilitation, it did not recover level comparable birds....

Exercise games (exergames) that combine both exercise and video gaming train people in a fun competitive manner to lead healthy lifestyle. Exergames promote more physical exertion help users easily independently any place. Many studies have been conducted evaluate the positive effects of exergames. However, most studies, heart rate was mainly used measure effect exercise. In this study, we according type (rest, walking, tennis, running) gameplay mode (single, competition, cooperation)...