A5101987988- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Nutrition and Health in Aging
- Gallbladder and Bile Duct Disorders
- Bariatric Surgery and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatic and Hepatic Oncology Research
- Appendicitis Diagnosis and Management
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Sarcoma Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Vascular Tumors and Angiosarcomas
- Cardiac Valve Diseases and Treatments
- Minimally Invasive Surgical Techniques
- Aortic Disease and Treatment Approaches
- Cancer Immunotherapy and Biomarkers
Boramae Medical Center
2015-2025
Seoul National University
2015-2025
Seoul Metropolitan Government
2011-2025
Seoul National University Hospital
2013-2024
City Of Hope National Medical Center
2020
New Generation University College
2009-2011
Samsung Medical Center
2006
Sungkyunkwan University
2006
Abstract BACKGROUND: The seventh TNM staging system for gastric cancer of the American Joint Committee on Cancer/International Union Against Cancer (AJCC/UICC) had a more detailed classification than sixth both tumor (T) and lymph nodes (N). authors compared survival rates assessed by with those system. METHODS: analyzed prospectively collected database patients who underwent surgery at Seoul National University Hospital between 1986 2006, calculated 9998 cases primary cancer, R0 resection,...
The pattern of gastric cancer in the Western world is changing, with an increased proportion tumours upper stomach. aim this study was to investigate changes clinicopathological features and survival patients resected at a single institution, area high incidence Far East.Clinical pathological findings were compared who underwent gastrectomy Seoul National University Hospital during four consecutive periods (1986-1990, 1991-1995, 1996-2000 2001-2006).There 12 026 patients. mean age from 53·4...
The purpose of this study is to analyze the relationship between number examined lymph nodes (NexLN) and survival in gastric cancer determine whether metastatic/examined node ratio (LN ratio) system can compensate for shortcomings UICC/AJCC staging.Prospective data 8949 primary T1-T4a patients who underwent curative surgery were reviewed. stratified by T-stage grouped according NexLN; 1 14 exLN denoted first group every subsequent 10 LNs thereafter. Numbers LN 5-year rates analyzed NexLN....
Abstract Background Preoperative accurate diagnosis of the T and N stages in early gastric cancer (EGC) is important determining application various limited treatments. The aim this study to analyze accuracy staging EGC with esophagogastroduodenoscopy (EGD), Stomach protocol CT (S‐CT), endoscopic ultrasonography (EUS), factors influencing accuracy. Methods Four hundred thirty‐four patients preoperatively diagnosed as using EGD or S‐CT undergoing curative gastrectomy at Seoul National...
An intestinal perforation is a rare condition, but has high mortality rate, even after immediate surgical intervention. The clinical predictors of postoperative morbidity and are still not well established, so this study attempted to identify risk factors for surgery an perforation.We retrospectively analyzed the cases 117 patients who underwent at single institution in Korea from November 2008 June 2014. Factors related with 1 month other complications were investigated.The mean age...
The incidence of gallstones has been reported to increase after gastrectomy. However, few studies have conducted on the prevention gallstone formation in patients who undergone gastrectomy.To evaluate efficacy and safety ursodeoxycholic acid (UDCA) preventing gastrectomy with gastric cancer.The PEGASUS-D study (Efficacy Safety DWJ1319 Prevention Gallstone Formation Gastrectomy Patient Gastric Cancer: A Multicenter, Randomized, Double-blind, Placebo-controlled Study) was a randomized,...
Purpose The purpose of this study is to investigate differentially expressed genes using DNA microarray between advanced gastric cancer (AGC) with aggressive lymph node (LN) metastasis and that a more tumor stage but without LN metastasis. Materials Methods Five sample pairs tissue normal mucosa were taken from three patients T3N3 (highN) two T4N0 (lowN). Data triplicate experiments analyzed, candidate identified volcano plot showed ≥ 2-fold differential expression significant by Welch's t...
Abstract Background The prognostic potential of PD-L1 is currently unclear in gastric carcinomas, although the immune checkpoint PD-1/PD-L1 inhibitors have produced promising results clinical trials. Methods We explored implications programmed death ligand 1 (PD-L1) 514 consecutive surgically-resected carcinomas. Overall survival and recurrence-free were evaluated. Immunohistochemistry for PD-L1, CD8, FOXP3, PD-1, molecular grouping by situ hybridization Epstein-Barr virus (EBV)-encoded...
A survey to evaluate the current status of bariatric and metabolic operations in Korea was conducted. Data from 5467 cases (32 hospitals) were collected. The annual numbers increased each year, 139 2003 1686 2013. Adjustable gastric band (AGB, 67.2 %) most common operation, followed by sleeve gastrectomy (SG, 14.2 %), Roux-en-Y bypass (RYGB, 12.7 %). Mean patient age body mass index (BMI) 35.4 years 35.9 kg/m2, respectively. In-hospital morbidity mortality rates 6 % (114/2305) 0.25 (5/2176),...
Reoperation is recommended for resectable retroperitoneal sarcoma (RS) recurrence; however, the long-term overall survival (OS) benefit varies. Although histologic grade an important OS predictor after primary tumor resection, its prognostic value tends to diminish with subsequent reoperations. The objective of this study was identify factors reoperation recurrent RS.The medical records 95 patients who underwent resection RS at Seoul National University Hospital between January 1999 and July...
Background Surgery for remnant gastric cancer (RGC) frequently fails to obtain the >15 lymph nodes necessary tumor‐node‐metastasis (TNM) staging. We aimed evaluate utility of recently developed tumor‐ratio‐metastasis (TRM) staging system. also examined pattern node metastasis and role prophylactic splenectomy in RGC. Methods Between May 2003 December 2012, data from 170 patients who underwent surgery RGC were retrospectively analyzed. Results arising after previous benign disease ( n =...